Imperial College London
Portrait Picture

Dr Alex Ivanov

Faculty of Natural Sciences, Department of Chemistry

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 5752alex.ivanov Website

 
 
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Assistant

 

Mr John Murrell +44 (0)20 7594 2845

 
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Location

 

110JMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Xue:2020:10.1038/s41578-020-0229-6,
author = {Xue, L and Yamazaki, H and Ren, R and Wanunu, M and Ivanov, AP and Edel, JB},
doi = {10.1038/s41578-020-0229-6},
journal = {Nature Reviews Materials},
pages = {931--951},
title = {Solid-state nanopore sensors},
url = {http://dx.doi.org/10.1038/s41578-020-0229-6},
volume = {5},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare. The predominant molecular readout method is based on measuring the temporal fluctuations in the ionic current through the pore. Recent advances in materials science and surface chemistries have not only enabled more robust and sensitive devices but also facilitated alternative detection modalities based on field-effect transistors, quantum tunnelling and optical methods such as fluorescence and plasmonic sensing. In this Review, we discuss recent advances in nanopore fabrication and sensing strategies that endow nanopores not only with sensitivity but also with selectivity and high throughput, and highlight some of the challenges that still need to be addressed.
AU  - Xue,L
AU  - Yamazaki,H
AU  - Ren,R
AU  - Wanunu,M
AU  - Ivanov,AP
AU  - Edel,JB
DO  - 10.1038/s41578-020-0229-6
EP  - 951
PY  - 2020///
SN  - 2058-8437
SP  - 931
TI  - Solid-state nanopore sensors
T2  - Nature Reviews Materials
UR  - http://dx.doi.org/10.1038/s41578-020-0229-6
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000571685700002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.nature.com/articles/s41578-020-0229-6
UR  - http://hdl.handle.net/10044/1/83652
VL  - 5
ER  -
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