Imperial College London


Faculty of MedicineDepartment of Infectious Disease

Professor of Infectious Diseases



+44 (0)20 3313 1283alison.holmes




8N16Hammersmith HospitalHammersmith Campus





Alison Holmes is a Professor of Infectious Diseases and the Director of both the NIHR Health Protection Research Unit in Healthcare Associated Infections and AMR and the Centre for Antimicrobial Optimisation (CAMO), at Imperial College London. She leads a large multidisciplinary infectious disease research programme focusing on antimicrobial resistance, epidemiology, public health, precision medicine and the development of emerging, innovative technologies to address infection prevention and management, antibiotic optimisation and AMR nationally and globally. She leads an ESRC international programme with collaborators in India and South Africa, as well as Wellcome Trust-funded projects led by colleagues in the Department of Electrical and Electronic Engineering and collaborators in Vietnam and Thailand.

Professor Holmes is a Fellow of the Academy of Medical Sciences, an NIHR Senior Investigator and, within Imperial College Healthcare NHS Trust, she is the Associate Medical Director, Director of Infection Prevention and Control, and an Infectious Disease consultant. Throughout her longstanding clinical and research career Professor Homes has conducted clinically applied research that influences local, national and international practice. She served as an expert member of the Governmental Advisory Committee on AMR and Healthcare Associated Infection for nine years and as a national expert witness for Parliamentary Health and Science and Technology Committees.

Professor Holmes is the current President of the International Society for Infectious Diseases, and serves on a variety of WHO Expert groups related to antimicrobial use, AMR, infection prevention and sepsis. In addition to her role as chair or advisor for numerous international scientific advisory boards, funding panels and editorial boards she is the outgoing Chair of the Fleming Fund’s Technical Advisory Group (Department of Health and Social Care), a Board Member of the Wellcome Trust’s Surveillance & Epidemiology of Drug-resistant Infections Consortium (SEDRIC) and has recently joined the Scientific Advisory Board of the Helmholtz Association of German Research Centres.

In response to the COVID-19 pandemic Professor Holmes has contributed to national COVID-19 responses through the UK Scientific Advisory Group for Emergencies (SAGE) Hospital Onset COVID-19 working group and her research group’s work in this field. She has also been active in the international responses through her roles with WHO on WHO COVID panels including the WHO R&D Expert Advisory Group for COVID-19 and the WHO Health Emergencies Program (WHE) Ad-Hoc Advisory Panel of Infection Prevention and Control Experts for Preparedness, Readiness and Response to COVID-19 (WHE-IPC-AP).

Selected Publications

Journal Articles

Birgand G, Castro-Sánchez E, Hansen S, et al., 2018, Comparison of governance approaches for the control of antimicrobial resistance: Analysis of three European countries, Antimicrobial Resistance and Infection Control, Vol:7, ISSN:2047-2994

Holmes AH, Holmes M, Gottlieb T, et al., 2018, End non-essential use of antimicrobials in livestock, Bmj, Vol:360, ISSN:0959-8138

Ardal C, Outterson K, Hoffman SJ, et al., 2016, International cooperation to improve access to and sustain effectiveness of antimicrobials, The Lancet, Vol:387, ISSN:0140-6736, Pages:296-307

Holmes AH, Moore LSP, Sundsfjord A, et al., 2015, Understanding the mechanisms and drivers of antimicrobial resistance, Lancet, Vol:387, ISSN:1474-547X, Pages:176-187

Charani E, Holmes AH, 2013, Antimicrobial stewardship programmes: the need for wider engagement, BMJ Quality & Safety, Vol:22, ISSN:2044-5415, Pages:885-887

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