Imperial College London
Alternate

ProfessorAlisonHolmes

Faculty of Medicine, Department of Infectious Disease

Professor of Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 3313 1283alison.holmes

 
 
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Location

 

8N16Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Charani:2023:10.1016/S2214-109X(23)00019-0,
author = {Charani, ESMITA and Mendelson, M and Pallett, S and Ahmad, R and Mpundu, M and Mbamalu, O and Bonaconsa, C and Nampoothiri, V and Singh, S and Peiffer-Smadja, N and Anton-Vazquez, V and Moore, L and Schouten, J and Kostyanev, T and Vlahovic-Palcevski, V and Kofteridis, D and Correa, J and Holmes, A},
doi = {10.1016/S2214-109X(23)00019-0},
journal = {The Lancet Global Health},
pages = {e466--e474},
title = {An analysis of existing National Action Plans for antimicrobial resistance – gaps and opportunities in strategies optimising antibiotic use in human populations},
url = {http://dx.doi.org/10.1016/S2214-109X(23)00019-0},
volume = {11},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - At the 2015 World Health Assembly, UN member states adopted a resolution that committed to the development of national action plans (NAPs) for antimicrobial resistance (AMR). The political determination to commit to NAPs and the availability of robust governance structures to assure sustainable translation of the identified NAP objectives from policy to practice remain major barriers to progress. Inter-country variability in economic and political resilience and resource constraints could be fundamental barriers to progressing AMR NAPs. Although there have been regional and global analyses of NAPs from a One Health and policy perspective, a global assessment of the NAP objectives targeting antimicrobial use in human populations is needed. In this Health Policy, we report a systematic evidence synthesis of existing NAPs that are aimed at tackling AMR in human populations. We find marked gaps and variability in maturity of NAP development and operationalisation across the domains of: (1) policy and strategic planning; (2) medicines management and prescribing systems; (3) technology for optimised antimicrobial prescribing; (4) context, culture, and behaviours; (5) operational delivery and monitoring; and (6) patient and public engagement and involvement. The gaps identified in these domains highlight opportunities to facilitate sustainable delivery and operationalisation of NAPs. The findings from this analysis can be used at country, regional, and global levels to identify AMR-related priorities that are relevant to infrastructure needs and contexts.
AU  - Charani,ESMITA
AU  - Mendelson,M
AU  - Pallett,S
AU  - Ahmad,R
AU  - Mpundu,M
AU  - Mbamalu,O
AU  - Bonaconsa,C
AU  - Nampoothiri,V
AU  - Singh,S
AU  - Peiffer-Smadja,N
AU  - Anton-Vazquez,V
AU  - Moore,L
AU  - Schouten,J
AU  - Kostyanev,T
AU  - Vlahovic-Palcevski,V
AU  - Kofteridis,D
AU  - Correa,J
AU  - Holmes,A
DO  - 10.1016/S2214-109X(23)00019-0
EP  - 474
PY  - 2023///
SN  - 2214-109X
SP  - 466
TI  - An analysis of existing National Action Plans for antimicrobial resistance – gaps and opportunities in strategies optimising antibiotic use in human populations
T2  - The Lancet Global Health
UR  - http://dx.doi.org/10.1016/S2214-109X(23)00019-0
UR  - https://www.sciencedirect.com/science/article/pii/S2214109X23000190?via%3Dihub
UR  - http://hdl.handle.net/10044/1/102669
VL  - 11
ER  -
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