Imperial College London

ProfessorAlisonHolmes

Faculty of MedicineDepartment of Infectious Disease

Professor of Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 3313 1283alison.holmes

 
 
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Location

 

8N16Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Karolcik:2023:10.1109/TBCAS.2023.3254453,
author = {Karolcik, S and Ming, D and Yacoub, S and Holmes, A and Georgiou, P},
doi = {10.1109/TBCAS.2023.3254453},
journal = {IEEE Transactions on Biomedical Circuits and Systems},
pages = {349--361},
title = {A multi-site, multi-wavelength PPG platform for continuous non-invasive health monitoring in hospital settings},
url = {http://dx.doi.org/10.1109/TBCAS.2023.3254453},
volume = {17},
year = {2023}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - This paper presents a novel PPG acquisition platform capable of synchronous multi-wavelength signal acquisition from two measurement locations with up to 4 independent wavelengths from each in parallel. The platform is fully configurable and operates at 1ksps, accommodating a wide variety of transmitters and detectors to serve as both a research tool for experimentation and a clinical tool for disease monitoring. The sensing probes presented in this work acquire 4 PPG channels from the wrist and 4 PPG channels from the fingertip, with wavelengths such that surrogates for pulse wave velocity and haematocrit can be extracted.For conventional PPG sensing, we have achieved the mean error of 4.08 ± 3.72 bpm for heart-rate and a mean error of 1.54 ± 1.04% for SpO2 measurement, with the latter lying within the FDA limits for commercial pulse oximeters. We have further evaluated over 700 individual peak-to-peak time differences between wrist and fingertip signals, achieving a normalized weighted average PWV of 5.80 ± 1.58 m/s, matching with values of PWV found for this age group in literature. Lastly, we introduced and computed a haematocrit ratio (Rhct) between the deep IR and deep red wavelength from the fingertip sensor, finding a significant difference between male and female values (median of 1.9 and 2.93 respectively) pointing to devices sensitivity to Hct.
AU - Karolcik,S
AU - Ming,D
AU - Yacoub,S
AU - Holmes,A
AU - Georgiou,P
DO - 10.1109/TBCAS.2023.3254453
EP - 361
PY - 2023///
SN - 1932-4545
SP - 349
TI - A multi-site, multi-wavelength PPG platform for continuous non-invasive health monitoring in hospital settings
T2 - IEEE Transactions on Biomedical Circuits and Systems
UR - http://dx.doi.org/10.1109/TBCAS.2023.3254453
UR - https://ieeexplore.ieee.org/document/10075465
UR - http://hdl.handle.net/10044/1/103401
VL - 17
ER -