Imperial College London
Portrait Picture

Professor Amanda Cross

Faculty of Medicine, School of Public Health

Professor of Cancer Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 3338amanda.cross

 
 
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Assistant

 

Mr Will Kay +44 (0)20 7594 3350

 
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Location

 

Room 1089Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Anderson:2020:10.1038/s41416-020-01155-2,
author = {Anderson, AS and Martin, RM and Renehan, AG and Cade, J and Copson, ER and Cross, AJ and Grimmett, C and Keaver, L and King, A and Riboli, E and Shaw, C and Saxton, JM and Beeken, R and Mitrou, G},
doi = {10.1038/s41416-020-01155-2},
journal = {British Journal of Cancer},
pages = {1057--1065},
title = {Cancer survivorship, excess body fatness and weight-loss intervention-where are we in 2020?},
url = {http://dx.doi.org/10.1038/s41416-020-01155-2},
volume = {124},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Earlier diagnosis and more effective treatments mean that the estimated number of cancer survivors in the United Kingdom is expected to reach 4 million by 2030. However, there is an increasing realisation that excess body fatness (EBF) is likely to influence the quality of cancer survivorship and disease-free survival. For decades, the discussion of weight management in patients with cancer has been dominated by concerns about unintentional weight loss, low body weight and interventions to increase weight, often re-enforced by the existence of the obesity paradox, which indicates that high body weight is associated with survival benefits for some types of cancer. However, observational evidence provides strong grounds for testing the hypothesis that interventions for promoting intentional loss of body fat and maintaining skeletal muscle in overweight and obese cancer survivors would bring important health benefits in terms of survival outcomes and long-term impact on treatment-related side effects. In this paper, we outline the need for studies to improve our understanding of the health benefits of weight-loss interventions, such as hypocaloric healthy-eating plans combined with physical activity. In particular, complex intervention trials that are pragmatically designed are urgently needed to develop effective, clinically practical, evidence-based strategies for reducing EBF and optimising body composition in people living with and beyond common cancers.
AU  - Anderson,AS
AU  - Martin,RM
AU  - Renehan,AG
AU  - Cade,J
AU  - Copson,ER
AU  - Cross,AJ
AU  - Grimmett,C
AU  - Keaver,L
AU  - King,A
AU  - Riboli,E
AU  - Shaw,C
AU  - Saxton,JM
AU  - Beeken,R
AU  - Mitrou,G
DO  - 10.1038/s41416-020-01155-2
EP  - 1065
PY  - 2020///
SN  - 0007-0920
SP  - 1057
TI  - Cancer survivorship, excess body fatness and weight-loss intervention-where are we in 2020?
T2  - British Journal of Cancer
UR  - http://dx.doi.org/10.1038/s41416-020-01155-2
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000599063400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.nature.com/articles/s41416-020-01155-2#article-info
UR  - http://hdl.handle.net/10044/1/85808
VL  - 124
ER  -
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