Publications

BibTex format

@article{Mayen:2022:10.1007/s10654-022-00900-6,
author = {Mayen, A-L and Viallon, V and Botteri, E and Proust-Lima, C and Bagnardi, V and Batista, V and Cross, AJ and Laouali, N and MacDonald, CJ and Severi, G and Katzke, V and Bergmann, MM and Schulze, MB and Tjonneland, A and Eriksen, AK and Dahm, CC and Antoniussen, CS and Jakszyn, P and Sanchez, M-J and Amiano, P and Colorado-Yohar, SM and Ardanaz, E and Travis, R and Palli, D and Sabina, S and Tumino, R and Ricceri, F and Panico, S and Bueno-de-Mesquita, B and Derksen, JWG and Sonestedt, E and Winkvist, A and Harlid, S and Braaten, T and Gram, IT and Lukic, M and Jenab, M and Riboli, E and Freisling, H and Weiderpass, E and Gunter, MJ and Ferrari, P},
doi = {10.1007/s10654-022-00900-6},
journal = {European Journal of Epidemiology},
pages = {915--929},
title = {A longitudinal evaluation of alcohol intake throughout adulthood and colorectal cancer risk},
url = {http://dx.doi.org/10.1007/s10654-022-00900-6},
volume = {37},
year = {2022}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundAlcohol intake is an established risk factor for colorectal cancer (CRC); however, there is limited knowledge on whether changing alcohol drinking habits during adulthood modifies CRC risk.ObjectiveLeveraging longitudinal exposure assessments on alcohol intake at different ages, we examined the relationship between change in alcohol intake and subsequent CRC risk.MethodsWithin the European Prospective Investigation into Cancer and Nutrition, changes in alcohol intake comparing follow-up with baseline assessments were investigated in relation to CRC risk. The analysis included 191,180, participants and 1530 incident CRC cases, with exclusion of the first three years of follow-up to minimize reverse causation. Trajectory profiles of alcohol intake, assessed at ages 20, 30, 40, 50 years, at baseline and during follow-up, were estimated using latent class mixed models and related to CRC risk, including 407,605 participants and 5,008 incident CRC cases.ResultsMean age at baseline was 50.2 years and the follow-up assessment occurred on average 7.1 years later. Compared to stable intake, a 12 g/day increase in alcohol intake during follow-up was positively associated with CRC risk (HR = 1.15, 95%CI 1.04, 1.25), while a 12 g/day reduction was inversely associated with CRC risk (HR = 0.86, 95%CI 0.78, 0.95). Trajectory analysis showed that compared to low alcohol intake, men who increased their alcohol intake from early- to mid- and late-adulthood by up to 30 g/day on average had significantly increased CRC risk (HR = 1.24; 95%CI 1.08, 1.42), while no associations were observed in women. Results were consistent by anatomical subsite.ConclusionsIncreasing alcohol intake during mid-to-late adulthood raised CRC risk, while reduction lowered risk.
AU  - Mayen,A-L
AU  - Viallon,V
AU  - Botteri,E
AU  - Proust-Lima,C
AU  - Bagnardi,V
AU  - Batista,V
AU  - Cross,AJ
AU  - Laouali,N
AU  - MacDonald,CJ
AU  - Severi,G
AU  - Katzke,V
AU  - Bergmann,MM
AU  - Schulze,MB
AU  - Tjonneland,A
AU  - Eriksen,AK
AU  - Dahm,CC
AU  - Antoniussen,CS
AU  - Jakszyn,P
AU  - Sanchez,M-J
AU  - Amiano,P
AU  - Colorado-Yohar,SM
AU  - Ardanaz,E
AU  - Travis,R
AU  - Palli,D
AU  - Sabina,S
AU  - Tumino,R
AU  - Ricceri,F
AU  - Panico,S
AU  - Bueno-de-Mesquita,B
AU  - Derksen,JWG
AU  - Sonestedt,E
AU  - Winkvist,A
AU  - Harlid,S
AU  - Braaten,T
AU  - Gram,IT
AU  - Lukic,M
AU  - Jenab,M
AU  - Riboli,E
AU  - Freisling,H
AU  - Weiderpass,E
AU  - Gunter,MJ
AU  - Ferrari,P
DO  - 10.1007/s10654-022-00900-6
EP  - 929
PY  - 2022///
SN  - 0393-2990
SP  - 915
TI  - A longitudinal evaluation of alcohol intake throughout adulthood and colorectal cancer risk
T2  - European Journal of Epidemiology
UR  - http://dx.doi.org/10.1007/s10654-022-00900-6
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000850029300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://link.springer.com/article/10.1007/s10654-022-00900-6
UR  - http://hdl.handle.net/10044/1/101139
VL  - 37
ER  -

Download

Professor Amanda Cross

Contact

Assistant

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)