Imperial College London

Professor DameMandyFisher

Faculty of MedicineInstitute of Clinical Sciences

Head of the Institute of Clinical Sciences
 
 
 
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Contact

 

+44 (0)20 3313 8236amanda.fisher

 
 
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Assistant

 

Ms Alessandra Lisini +44 (0)20 3313 8236

 
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Location

 

CRB (Clinical Research Building)Hammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

121 results found

Stock JK, Giadrossi S, Casanova M, Brookes E, Vidal M, Koseki H, Brockdorff N, Fisher AG, Pombo Aet al., 2007, Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells, NATURE CELL BIOLOGY, Vol: 9, Pages: 1428-U174, ISSN: 1465-7392

JOURNAL ARTICLE

Takousis P, Johonnett P, Williamson J, Sasieni P, Warnes G, Forshew T, Azuara V, Fisher A, Wu P-J, Jones T, Vatcheva R, Beck S, Sheer Det al., 2007, Replication timing profile reflects the distinct functional and genomic features of the MHC class II region, CELL CYCLE, Vol: 6, Pages: 2393-2398, ISSN: 1538-4101

JOURNAL ARTICLE

Frye M, Fisher AG, Watt FM, 2007, Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation, PLOS ONE, Vol: 2, ISSN: 1932-6203

JOURNAL ARTICLE

Lande-Diner L, Zhang J, Ben-Porath I, Amariglio N, Keshet I, Hecht M, Azuara V, Fisher AG, Rechavi G, Cedar Het al., 2007, Role of DNA methylation in stable gene repression, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 282, Pages: 12194-12200, ISSN: 0021-9258

JOURNAL ARTICLE

Spivakov M, Fisher AG, 2007, Epigenetic signatures of stem-cell identity, NATURE REVIEWS GENETICS, Vol: 8, Pages: 263-271, ISSN: 1471-0056

JOURNAL ARTICLE

Giadrossi S, Dvorkina M, Fisher AG, 2007, Chromatin organization and differentiation in embryonic stem cell models, CURRENT OPINION IN GENETICS & DEVELOPMENT, Vol: 17, Pages: 132-138, ISSN: 0959-437X

JOURNAL ARTICLE

Thompson EC, Cobb BS, Sabbattini P, Meixlsperger S, Parelho V, Liberg D, Taylor B, Dillon N, Georgopoulos K, Jumaa H, Smale ST, Fisher AG, Merkenschlager Met al., 2007, Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits, IMMUNITY, Vol: 26, Pages: 335-344, ISSN: 1074-7613

JOURNAL ARTICLE

Jorgensen HF, Azuara V, Amoils S, Spivakov M, Terry A, Nesterova T, Cobb BS, Ramsahoye B, Merkenschlager M, Fisher AGet al., 2007, The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells, GENOME BIOLOGY, Vol: 8, ISSN: 1474-760X

JOURNAL ARTICLE

Roessler S, Gyoery I, Imhof S, Spivakov M, Williams RR, Busslinger M, Fisher AG, Grosschedl Ret al., 2007, Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5, MOLECULAR AND CELLULAR BIOLOGY, Vol: 27, Pages: 579-594, ISSN: 0270-7306

JOURNAL ARTICLE

Cobb BS, Hertweck A, Smith J, O'Connor E, Graf D, Cook T, Smale ST, Sakaguchi S, Livesey FJ, Fisher AG, Merkenschlager Met al., 2006, A role for Dicer in immune regulation, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 203, Pages: 2519-2527, ISSN: 0022-1007

JOURNAL ARTICLE

Jorgensen HF, Giadrossi S, Casanova M, Endoh M, Koseki H, Brockdorff N, Fisher AGet al., 2006, Stem cells primed for action - Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells, CELL CYCLE, Vol: 5, Pages: 1411-1414, ISSN: 1538-4101

JOURNAL ARTICLE

Terranova R, Pereira CF, Du Roure C, Merkenschlager M, Fisher AGet al., 2006, Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming, JOURNAL OF CELL SCIENCE, Vol: 119, Pages: 2065-2072, ISSN: 0021-9533

JOURNAL ARTICLE

Azuara V, Perry P, Sauer S, Spivakov M, Jorgensen HF, John RM, Gouti M, Casanova M, Warnes G, Merkenschlager M, Fisher AGet al., 2006, Chromatin signatures of pluripotent cell lines, NATURE CELL BIOLOGY, Vol: 8, Pages: 532-U189, ISSN: 1465-7392

JOURNAL ARTICLE

Du Roure C, Takacs K, Maxwell PH, Roberts I, Dazzi F, Cannella L, Merkenschlager M, Fisher AGet al., 2006, Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment, BRITISH JOURNAL OF HAEMATOLOGY, Vol: 132, Pages: 608-614, ISSN: 0007-1048

JOURNAL ARTICLE

Williams RRE, Azuara V, Perry P, Sauer S, Dvorkina M, Jorgensen H, Roix J, McQueen P, Misteli T, Merkenschlager M, Fisher AGet al., 2006, Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus, JOURNAL OF CELL SCIENCE, Vol: 119, Pages: 132-140, ISSN: 0021-9533

JOURNAL ARTICLE

Terranova R, Sauer S, Merkenschlager M, Fisher AGet al., 2005, The reorganisation of constitutive heterochromatin in differentiating muscle requires HDAC activity, EXPERIMENTAL CELL RESEARCH, Vol: 310, Pages: 344-356, ISSN: 0014-4827

JOURNAL ARTICLE

Cobb BS, Nesterova TB, Thompson E, Hertweck A, O'Connor E, Godwin J, Wilson CB, Brockdorff N, Fisher AG, Smale ST, Merkenschlager Met al., 2005, T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 201, Pages: 1367-1373, ISSN: 0022-1007

JOURNAL ARTICLE

Merkenschlager M, Amoils S, Roldan E, Rahemtulla A, O'Connor E, Fisher AG, Brown KEet al., 2004, Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 200, Pages: 1437-1444, ISSN: 0022-1007

JOURNAL ARTICLE

Hewitt SL, High FA, Reiner SL, Fisher AG, Merkenschlager Met al., 2004, Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 34, Pages: 3604-3613, ISSN: 0014-2980

JOURNAL ARTICLE

Perry P, Sauer S, Billon N, Richardson WD, Spivakov M, Warnes G, Livesey FJ, Merkenschlager M, Fisher AG, Azuara Vet al., 2004, A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction, CELL CYCLE, Vol: 3, Pages: 1645-1650, ISSN: 1538-4101

JOURNAL ARTICLE

Takacs K, Du Roure C, Nabarro S, Dillon N, McVey JH, Webster Z, MacNeil A, Bartok L, Higgins C, Gray D, Merkenschlager M, Fisher AGet al., 2004, The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 16298-16303, ISSN: 0027-8424

JOURNAL ARTICLE

Baxter J, Sauer S, Peters A, John R, Williams R, Caparros ML, Arney K, Otte A, Jenuwein T, Merkenschlager M, Fisher AGet al., 2004, Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes, EMBO JOURNAL, Vol: 23, Pages: 4462-4472, ISSN: 0261-4189

JOURNAL ARTICLE

Arney KL, Fisher AG, 2004, Epigenetic aspects of differentiation, JOURNAL OF CELL SCIENCE, Vol: 117, Pages: 4355-4363, ISSN: 0021-9533

JOURNAL ARTICLE

Su RC, Brown KE, Saaber S, Fisher AG, Merkenschlager M, Smale STet al., 2004, Dynamic assembly of silent chromatin during thymocyte maturation, NATURE GENETICS, Vol: 36, Pages: 502-506, ISSN: 1061-4036

JOURNAL ARTICLE

Azuara V, Brown KE, Williams RRE, Webb N, Dillon N, Festenstein R, Buckle V, Merkenschlager M, Fisher AGet al., 2003, Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication, NATURE CELL BIOLOGY, Vol: 5, Pages: 668-U49, ISSN: 1465-7392

JOURNAL ARTICLE

Williams RRE, Fisher AG, 2003, Chromosomes, positions please!, NATURE CELL BIOLOGY, Vol: 5, Pages: 388-390, ISSN: 1465-7392

JOURNAL ARTICLE

Azuara V, Fisher AG, 2003, Maintaining Transcriptional States Through DNA Replication, CELL CYCLE, Vol: 2, Pages: 521-524, ISSN: 1538-4101

JOURNAL ARTICLE

Fisher AG, 2002, Cellular identity and lineage choice, NATURE REVIEWS IMMUNOLOGY, Vol: 2, Pages: 977-982, ISSN: 1474-1733

JOURNAL ARTICLE

Graf D, Nethisinghe S, Palmer DB, Fisher AG, Merkenschlager Met al., 2002, The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 196, Pages: 163-171, ISSN: 0022-1007

JOURNAL ARTICLE

Baxter J, Merkenschlager M, Fisher AG, 2002, Nuclear organisation and gene expression, CURRENT OPINION IN CELL BIOLOGY, Vol: 14, Pages: 372-376, ISSN: 0955-0674

JOURNAL ARTICLE

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