Publications
278 results found
Mackintosh JA, Desai SR, Adamali H, et al., 2019, In patients with idiopathic pulmonary fibrosis the presence of hiatus hernia is associated with disease progression and mortality, European Respiratory Journal, Vol: 53, ISSN: 0903-1936
Jacob J, Pienn M, Payer C, et al., 2019, Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure-function study, RESPIROLOGY, Vol: 24, Pages: 445-452, ISSN: 1323-7799
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- Citations: 16
Barnett J, Devaraj A, 2019, Computed Tomographic Imaging in Connective Tissue Diseases, SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 40, Pages: 159-172, ISSN: 1069-3424
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- Citations: 3
Wells A, Devaraj A, Renzoni EA, et al., 2019, Multidisciplinary Evaluation in Patients with Lung Disease Associated with Connective Tissue Disease, SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 40, Pages: 184-193, ISSN: 1069-3424
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- Citations: 15
Rosenthal R, Cadieux EL, Salgado R, et al., 2019, Neoantigen-directed immune escape in lung cancer evolution, NATURE, Vol: 567, Pages: 479-+, ISSN: 0028-0836
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- Citations: 483
Jacob J, Hirani N, van Moorsel CHM, et al., 2019, Predicting outcomes in rheumatoid arthritis related interstitial lung disease, European Respiratory Journal, Vol: 53, ISSN: 0903-1936
Aims: To compare radiology-based prediction models in rheumatoid arthritis-related interstitial lung disease (RA-ILD) to identify patients with a progressive fibrosis phenotype.Methods: RAILD patients had CTs scored visually and by CALIPER and forced vital capacity (FVC) measurements. Outcomes were evaluated using three techniques: 1.Scleroderma system evaluating visual ILD extent and FVC values; 2.Fleischer Society IPF diagnostic guidelines applied to RAILD; 3.CALIPER scores of vessel-related structures (VRS). Outcomes were compared to IPF patients.Results: On univariable Cox analysis, all three staging systems strongly predicted outcome: Scleroderma System:HR=3.78, p=9×10-5; Fleischner System:HR=1.98, p=2×10-3; 4.4% VRS threshold:HR=3.10, p=4×10-4 When the Scleroderma and Fleischner Systems were combined, termed the Progressive Fibrotic System (C-statistic=0.71), they identified a patient subset (n=36) with a progressive fibrotic phenotype and similar 4-year survival to IPF.On multivariable analysis, with adjustment for patient age, gender and smoking status, when analysed alongside the Progressive Fibrotic System, the VRS threshold of 4.4% independently predicted outcome (Model C-statistic=0.77).Conclusions: The combination of two visual CT-based staging systems identified 23% of an RAILD cohort with an IPF-like progressive fibrotic phenotype. The addition of a computer-derived VRS threshold further improved outcome prediction and model fit, beyond that encompassed by RAILD measures of disease severity and extent.
Horst C, Ruparel M, Dickson J, et al., 2019, Optimising nodule management with data from the Lung Screen Uptake Trial, Publisher: ELSEVIER IRELAND LTD, Pages: S22-S22, ISSN: 0169-5002
Barnett J, Pulzato I, Padley S, et al., 2019, Radiological-pathological correlation of negative CT biopsy results enables high negative predictive value for thoracic malignancy, Publisher: ELSEVIER IRELAND LTD, Pages: S16-S16, ISSN: 0169-5002
Woznitza N, Devaraj A, Janes S, et al., 2019, Impact of radiographer immediate reporting of chest x-rays from general practice on the lung cancer pathway (radioX), Publisher: ELSEVIER IRELAND LTD, Pages: S13-S13, ISSN: 0169-5002
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- Citations: 2
Ruparel M, Dickson J, Quaife S, et al., 2019, Results from a prevalence round of LDCT screening for lung cancer in the Lung Screen Uptake Trial, Publisher: ELSEVIER IRELAND LTD, Pages: S22-S23, ISSN: 0169-5002
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- Citations: 2
Jacob J, Pienn M, Payer C, et al., 2019, Normalized Vessel Volume from Quantitative Computed Tomography Predicts Survival in Idiopathic Pulmonary Fibrosis, International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Flaherty KR, Wells AU, Clerisme-Beaty E, et al., 2019, Characteristics of Patients with Progressive Fibrosing Interstitial Lung Diseases (ILDs) in the INBUILD Trial of Nintedanib, International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Shen M, Tenda ED, McNulty W, et al., 2019, Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils, RESPIRATION, Vol: 98, Pages: 70-81, ISSN: 0025-7931
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- Citations: 9
Ruparel M, Quaife SL, Dickson JL, et al., 2019, Prevalence, Symptom Burden and Under-Diagnosis of COPD in a Lung Cancer Screening Cohort, International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
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- Citations: 1
Ruparel M, Quaife SL, Dickson JL, et al., 2019, Is Lung Cancer Screening an Opportunity to Reduce Cardiovascular Mortality?, International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Barnett J, Molyneaux PL, Rawal B, et al., 2019, Radiological Fibrosis Score Predicts Bronchoalveolar Lavage Lymphocytosis in Fibrosing Lung Disease, International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Walsh SLF, Devaraj A, Enghelmayer JI, et al., 2018, Role of imaging in progressive-fibrosing interstitial lung diseases, EUROPEAN RESPIRATORY REVIEW, Vol: 27, ISSN: 0905-9180
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- Citations: 46
Nair A, Bartlett EC, Walsh SLF, et al., 2018, Variable radiological lung nodule evaluation leads to divergent management recommendations, EUROPEAN RESPIRATORY JOURNAL, Vol: 52, ISSN: 0903-1936
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- Citations: 21
Ratnakumar S, Madani Y, Aboelhassan S, et al., 2018, ADVANCED STAGE AND AGGRESSIVE CANCERS FORM A CONSIDERABLE PROPORTION OF LUNG MALIGNANCIES IN IDIOPATHIC PULMONARY FIBROSIS AND SCLERODERMA-ASSOCIATED ILD, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A146-A147, ISSN: 0040-6376
Chua F, George P, Devaraj A, et al., 2018, PLEURO-PARENCHYMAL FIBROELASTOSIS: TRACTION BRONCHIECTASIS AND EXTENT OF PLATYTHORAX ON COMPUTED TOMOGRAPHY ARE DETERMINANTS OF DISEASE PROGRESSION AND MORTALITY, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A46-A47, ISSN: 0040-6376
Kouranos V, Ward S, Kokosi M, et al., 2018, MIXED VENTILATORY DEFECTS IN PULMONARY SARCOIDOSIS: PREVALENCE AND CLINICAL FEATURES, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A90-A90, ISSN: 0040-6376
Veiga C, Landau D, Devaraj A, et al., 2018, Novel CT-Based Objective Imaging Biomarkers of Long-Term Radiation-Induced Lung Damage, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol: 102, Pages: 1287-1298, ISSN: 0360-3016
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- Citations: 7
Veiga C, Landau D, Devaraj A, et al., 2018, Objective CT-Based Imaging Biomarkers of Radiation-Induced Lung Damage, 60th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), Publisher: ELSEVIER SCIENCE INC, Pages: S70-S71, ISSN: 0360-3016
Kouranos V, Ward S, Kokosi M, et al., 2018, Mixed ventilatory defects in pulmonary sarcoidosis: prevalence and prognosis, 28th International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 1
George P, Armstrong-James D, Devaraj A, et al., 2018, Traction bronchiectasis and platythorax on computed tomography are determinants of progression and mortality in pleuroparenchymal fibroelastosis, 28th International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 1
Bax S, Jacobs J, Kouranos V, et al., 2018, 10 years' experience of referral of ILD patients with Suspected PH to a National PH Service: Demographics and Outcomes, 28th International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Boccabella C, Macaluso C, Kokosi M, et al., 2018, Pulmonary function trends predict mortality in patients with hypersensitivity pneumonitis, 28th International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 2
Tavare AN, Hare SS, Miller FNA, et al., 2018, A survey of UK percutaneous lung biopsy practice: current practices in the era of early detection, oncogenetic profiling, and targeted treatments, CLINICAL RADIOLOGY, Vol: 73, Pages: 800-809, ISSN: 0009-9260
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- Citations: 6
Nair A, Devaraj A, Callister MEJ, et al., 2018, The Fleischner Society 2017 and British Thoracic Society 2015 guidelines for managing pulmonary nodules: keep calm and carry on, THORAX, Vol: 73, Pages: 806-812, ISSN: 0040-6376
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- Citations: 9
Schreuder A, van Ginneken B, Scholten ET, et al., 2018, Classification of CT Pulmonary Opacities as Perifissural Nodules: Reader Variability, RADIOLOGY, Vol: 288, Pages: 867-875, ISSN: 0033-8419
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- Citations: 28
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