128 results found
O'Callaghan DJP, Gordon AC, 2011, Sepsis: an update for physicians, Clinical Medicine, Vol: 11, Pages: 619-622
Mehta S, Granton J, Lapinsky SE, et al., 2011, Agreement in electrocardiogram interpretation in patients with septic shock, CRITICAL CARE MEDICINE, Vol: 39, Pages: 2080-2086, ISSN: 0090-3493
Tridente A, Clarke GM, Walden A, et al., 2011, EPIDEMIOLOGY OF FAECAL PERITONITIS IN THE GENOSEPT COHORT, Publisher: SPRINGER, Pages: S199-S199, ISSN: 0342-4642
O'Callaghan DJ, O'Dea KP, Gordon AC, et al., 2011, MONOCYTE TACE ACTIVITY PROFILES ARE ALTERED BY INFLAMMATORY STIMULI, INTENSIVE CARE MEDICINE, Vol: 37, Pages: S258-S258, ISSN: 0342-4642
O'Callaghan DJ, O'Dea KP, Gordon AC, et al., 2011, MONOCYTE TACE ACTIVITY MAY RESPOND TO ENVIRONMENTAL STIMULI, INTENSIVE CARE MEDICINE, Vol: 37, Pages: S258-S258, ISSN: 0342-4642
Gordon AC, Hartle AJ, 2011, Donation after circulatory death – a new role for the anaesthetist?, Anaesthesia, Vol: 66, Pages: 757-768
Gordon AC, 2011, Vasopressor therapy, Encyclopedia of Intensive Care Medicine, Editors: Vincent, Hall, Publisher: Springer Verlag, ISBN: 9783642004179
Gordon AC, 2011, Vasopressin in septic shock, Journal of the Intensive Care Society, Vol: 12, Pages: 11-14, ISSN: 1751-1437
In recent years there has been growing interest in the use of vasopressin as an adjunctive vasopressor in septic shock. This review article aims to summarise the rationale for its use, review the evidence of its effects in clinical studies and consider future areas of research.©The Intensive Care Society 2011.
Gordon AC, 2011, Vasopressin in septic shock, Jounal of the Intensive Care Society, Vol: 1, Pages: 11-14
Gordon AC, Russell JA, Walley KR, et al., 2010, The effects of vasopressin on acute kidney injury in septic shock, INTENSIVE CARE MEDICINE, Vol: 36, Pages: 83-91, ISSN: 0342-4642
Russell JA, Gordon AC, Walley KR, 2010, Corticosteroids and the original vasopressin and septic shock trial subgroups Reply, CRITICAL CARE MEDICINE, Vol: 38, Pages: 338-339, ISSN: 0090-3493
Gordon AC, Russell JA, 2010, Should vasopressin be used in septic shock?, Evidence-based practice of critical care, Editors: Deutschman, Neligan, Publisher: W B Saunders Co, ISBN: 9781416054764
An outstanding source for "best practices" in critical care medicine, thisbook is a valuable framework for translating evidence into practice.
Gordon AC, Mehta S, Lapinsky S, et al., 2009, COMPARISON OF VASOPRESSIN- VERSUS NOREPINEPHRINE-ASSOCIATED ISCHEMIC ECG CHANGES IN SEPTIC SHOCK, 22nd Annual Congress of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: 114-114, ISSN: 0342-4642
Russell JA, Walley KR, Gordon AC, et al., 2009, Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock., Critical Care Medicine, Vol: 37, Pages: 811-818
Vasopressin and corticosteroids are often added to support cardiovascular dysfunction in patients who have septic shock that is nonresponsive to fluid resuscitation and norepinephrine infusion. However, it is unknown whether vasopressin treatment interacts with corticosteroid treatment.
van Saene HKF, Petros AJ, Sarginson RE, et al., 2009, Is selective decontamination of the digestive tract a solution to the antimicrobial resistance problem in the UK, Journal of the Intensive Care Society, Vol: 2, Pages: 86-87
Wurfel MM, Gordon AC, Holden TD, et al., 2008, Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 178, Pages: 710-720, ISSN: 1073-449X
Eisen DP, Dean MM, Boermeester MA, et al., 2008, Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection, CLINICAL INFECTIOUS DISEASES, Vol: 47, Pages: 510-516, ISSN: 1058-4838
Gordon A, Knight JC, Hinds CJ, 2008, Genes and sepsis: How tight is the fit?, CRITICAL CARE MEDICINE, Vol: 36, Pages: 1652-1654, ISSN: 0090-3493
Russell JA, Walley KR, Singer J, et al., 2008, Vasopressin versus norepinephrine infusion in patients with septic shock, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 358, Pages: 877-887, ISSN: 0028-4793
Gordon AC, LeBlanc ME, Walley KR, et al., 2007, Protein C and PAI-1 genetic markers of mortality reduction in response to rhAPC in the VASST study, 37th Critical Care Congress of the Society-of-Critical-Care-Medicine, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: A18-A18, ISSN: 0090-3493
Gordon AC, Walley KR, Russell JA, et al., 2006, Hyperfunctioning polymorphism in the toll-like receptor 1 gene is associated with increased mortality in sepsis., CRITICAL CARE MEDICINE, Vol: 34, Pages: A18-A18, ISSN: 0090-3493
Sutherland AM, Gordon AC, Russell JA, 2006, Are Vasopressin Levels Increased or Decreased in Septic Shock?, Critical Care Medicine, Vol: 34, Pages: 542-543
Manocha S, Gordon AC, Salehifar E, et al., 2006, Inhaled beta-2 agonist salbutamol and acute lung injury: An association with improvement in acute lung injury, Critical Care, Vol: 10, ISSN: 1364-8535
Introductionβ2 agonists have several properties that could be beneficial in acute lung injury (ALI). We therefore chose to study the effect of inhaled β2 agonist use (salbutamol) on duration and severity of ALI.MethodsWe undertook a retrospective chart review of 86 consecutive mechanically ventilated patients with ALI, who had varying exposure to inhaled salbutamol. The cohort was divided into two groups according to the average daily dose of inhaled salbutamol they received ('high dose' ≥ 2.2 mg/day and 'low dose' <2.2 mg/day). Severity of ALI and non-pulmonary organ dysfunction was compared between the groups by calculating the days alive and free of ALI and other organ dysfunctions.ResultsThe high dose and low dose groups received a mean of 3.72 mg and 0.64 mg salbutamol per day, respectively. The high dose salbutamol group had significantly more days alive and free of ALI than the low dose group (12.2 ± 4.4 days versus 7.6 ± 1.9 days, p = 0.02). There were no associations between dose of β agonist and non-pulmonary organ dysfunctions. High dose salbutamol (p = 0.04), APACHE II score (p = 0.02), and cause of ALI (p = 0.02) were independent variables associated with number of days alive and free of ALI in a multivariate linear regression model.ConclusionOur retrospective study suggests that salbutamol, an inhaled β2 agonist, is associated with a shorter duration and lower severity of ALI. A dose greater than 2.2 mg/day of inhaled salbutamol could be a minimal effective dose to evaluate in a randomized controlled trial.
Gordon AC, Russell JA, 2006, Reduction in airway epithelial chloride transport in septicaemia related pulmonary oedema reversible by beta agonist application - Response, CRITICAL CARE, Vol: 10, ISSN: 1466-609X
Gordon AC, Waheed U, Hansen TK, et al., 2006, Mannose-binding lectin polymorphisms in severe sepsis: Relationship to levels, incidence, and outcome, SHOCK, Vol: 25, Pages: 88-93, ISSN: 1073-2322
Gordon AC, Russell JA, 2005, Goal directed therapy: How long can we wait?, Critical Care, Vol: 9, Pages: 647-648, ISSN: 1364-8535
Intensive monitoring and aggressive management of perioperative haemodynamics (goal directed therapy) have repeatedly been reported to reduce the significant morbidity and mortality associated with high risk surgery. It may not matter what particular monitor is used to assess cardiac output but it is essential to ensure adequate oxygen delivery. If this management cannot begin preoperatively, it is still worth beginning goal directed therapy in the immediate postoperative period.
Gordon A, 2005, A response to 'Incidence and outcome of critical illness amongst hospitalised patients with haematological malignance: a prospective observational study of ward and intensive care unit based care' - Reply, ANAESTHESIA, Vol: 60, Pages: 945-946, ISSN: 0003-2409
Szawarski P, 2005, A response to 'Incidence and outcome of critical illness amongst hospitalised patients with haematological malignance: a prospective observational study of ward and intensive care unit based care'., Anaesthesia, Vol: 60, ISSN: 0003-2409
Gordon AC, Oakervee HE, Kaya B, et al., 2005, Incidence and outcome of critical illness amongst hospitalised patients with haematological malignancy: a prospective observational study of ward and intensive care unit based care, ANAESTHESIA, Vol: 60, Pages: 340-347, ISSN: 0003-2409
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