Imperial College London

Dr Apoorva D. Srivastava

Faculty of Natural SciencesDepartment of Chemistry

Research Associate in Chemoenzymatic Oligosaccharide Synthes







Molecular Sciences Research HubWhite City Campus





Apoorva started her research career with a master's in Organic Chemistry, followed by a PhD under the guidance of Professor Geert Jan Boons in University of Georgia (USA) and Utrecht University (The Netherlands). In the Boons group, she worked on the chemo-enzymatic synthesis of N-glycans and their effects on immunomodulatory proteins.

After a short industrial stint where she worked on the synthesis of novel drug candidates pertaining to small molecules as well as sugars, she joined Imperial College in July 2022 as a Post-Doctoral Research Associate with Dr Ben Schumann in the Department of Chemistry, where she will work on various chemo-enzymatic and chemical biology techniques to understand the physiological roles of carbohydrates. In a joint collaboration with the Glycoscience laboratory lead by Prof. Ten Feizi and Dr. Yan Liu,  she is also a member of the Carbohydrate Microarray Facility supported by Wellcome Trust where she will be involved in the design and expansion of carbohydrate recognizing probes in micro-array studies.


A.D. Srivastava, L. Unione, M. Bunyatov, I.A. Gagarinov, N.G.A. Abrescia, S. Delgado, A. Ardá and G.J. Boons. Chemoenzymatic synthesis of complex N-glycans of the parasite S. mansoni to examine the importance of epitope presentation on DC-SIGN recognition. 2021, Angew. Chem. Int. Ed., 60, 19287-19296. DOI

A.D. Srivastava, L. Unione, P. Valverde, M.A. Wolfert, A. Ardá, J. Jiménez-Barbero and G.J.  Boons. Mono- and Di-Fucosylated glycans of the parasitic worm S. mansoni are recognized differently by the innate immune receptor DC-SIGN. 2020, Chem. Eur. J., 26, 15605-15612. DOI

Sastre-Toraño, I.A. Gagarinov, G.M. Vos, F. Broszeit, A.D. Srivastava, M. Palmer, J.I. Langridge, O. Aizpurua-Olaizola, V.J. Somovilla, and G.J. Boons. Ion-mobility spectrometry can assign exact fucosyl positions in glycans and prevent misinterpretation of mass spectrometry data after gas-phase rearrangement. 2019, Angew. Chem. Int. Ed.,58(49), 17616-17620. DOI

I.A. Gagarinov, T. Li, J. Sastre Torano, T. Caval, A.D. Srivastava, J.A.W. Kruijtzer, A.J.R. Heck and G.J. Boons. Chemoenzymatic Approach for the Preparation of Asymmetric bi-, tri- and tetra-antennary N-Glycans from a common precursor. 2017, J. Am. Chem. Soc., 139(2), 1011-1018. DOI

I.A. Gagarinov, T. Fang, L. Liu, A.D. Srivastava and G.J. Boons. Synthesis of Staphylococcus Aureus Type 5 Trisachharide Repeating Unit: Solving the problem of Lactamization. 2015, Org. Lett., 17(4), 928-931. DOI

I.A. Gagarinov, A.D. Srivastava, G.J. Boons and Z. Wang. 2017. A multigram synthesis of phenyl 2-azido-3-O-benzyl-2-deoxy-4,6-O-benzylidene-1-thio-α-D-mannopyranoside. 2017, (Chapter 21), Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 (C. Vogel and P. Murphy, eds).

I.A. Gagarinov, S. Visansirikul, A.D. Srivastava and G.J. Boons. Simplifying access to 3,4-di-O-acetyl-D-fucal 2017, (Chapter 24), Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 (C. Vogel and P. Murphy, eds).



Srivastava AD, Unione L, Bunyatov M, et al., 2021, Chemoenzymatic Synthesis of Complex <i>N</i> ‐Glycans of the Parasite <i>S. mansoni</i> to Examine the Importance of Epitope Presentation on DC‐SIGN recognition, Angewandte Chemie International Edition, Vol:60, ISSN:1433-7851, Pages:19287-19296

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