Imperial College London
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Dr Ben Almquist FIMMM

Faculty of Engineering, Department of Bioengineering

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 6494b.almquist Website

 
 
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Location

 

413Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mager:2008:10.1021/la802726u,
author = {Mager, MD and Almquist, B and Melosh, NA},
doi = {10.1021/la802726u},
journal = {Langmuir},
pages = {12734--12737},
title = {Formation and Characterization of Fluid Lipid Bilayers on Alumina},
url = {http://dx.doi.org/10.1021/la802726u},
volume = {24},
year = {2008}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Fluid lipid bilayers were deposited on alumina substrates with the use of bubble collapse deposition (BCD). Previous studies using vesicle rupture have required the use of charged lipids or surface functionalization to induce bilayer formation on alumina, but these modifications are not necessary with BCD. Photobleaching experiments reveal that the diffusion coefficient of POPC on alumina is 0.6 μm2/s, which is much lower than the 1.4-2.0 μm2/s reported on silica. Systematically accounting for roughness, immobile regions and membrane viscosity shows that pinning sites account for about half of this drop in diffusivity. The remainder of the difference is attributed to a more tightly bound water state on the alumina surface, which induces a larger drag on the bilayer.
AU  - Mager,MD
AU  - Almquist,B
AU  - Melosh,NA
DO  - 10.1021/la802726u
EP  - 12737
PY  - 2008///
SN  - 0743-7463
SP  - 12734
TI  - Formation and Characterization of Fluid Lipid Bilayers on Alumina
T2  - Langmuir
UR  - http://dx.doi.org/10.1021/la802726u
VL  - 24
ER  -
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