Summary
I use a novel combination of experimental, mathematical and bioinformatic techniques to investigate cell-mediated immunity. My aim is to develop a predictive mathematical model of the human in vivo CD8+ T cell response in order to prevent and alleviate viral infection.
Members of the GrouP
Current
David Vickers
Recent
Nafisa-Katrin Seich al Basatena
Ulrich Kadolsky (u.kadolsky01@imperial.ac.uk)
Aidan Macnamara (aidan.macnamara@gmail.com)
Sukhdeep Singh (sukhdeepsingh.bio@googlemail.com)
Background
My initial training was in theoretical physics. I have a BSc in Physics (1st class hons. University College London), an MSc in Mathematics (distinction, Imperial College London) and a PhD in Theoretical Particle Physics (title: "Non Commutative Geometry", University of Durham). I then worked as a mathematical modeller for the UK government for 2 years before crossing disciplines to Mathematical Immunology. I held a Wellcome Trust Fellowship at Imperial College London and then a Leverhulme Trust Fellowship at the University of Oxford before returning to Imperial as a lecturer.
For research interests and selected publications please see my group webpage.
oPPORTUNITIES
Funded PhD positions available:
Please contact me if you wish to discuss these opportunities further.
software
Publications
Journals
Mora Bitria L, Asquith R, 2023, Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections, Immunogenetics, ISSN:0093-7711, Pages:1-14
Day S, Kaur C, Cheeseman H, et al., 2022, Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens, Frontiers in Immunology, Vol:13, ISSN:1664-3224, Pages:1-17
Cuthill KM, Zhang Y, Pepper A, et al., 2022, Identification of proliferative and non-proliferative subpopulations of leukemic cells in CLL, Leukemia, Vol:36, ISSN:0887-6924, Pages:2233-2241
Zhang S, Asquith B, Szydlo R, et al., 2021, Peripheral T cell lymphopenia in COVID-19: potential mechanisms and impact, Immunotherapy Advances, Vol:1, ISSN:2732-4303, Pages:1-18
Conference
Mora-Bitria L, McQuibban NAR, Niederalt C, et al., 2022, Inhibitory KIRS decrease HLA class II-mediated protection in type 1 diabetes, WILEY, Pages:423-424, ISSN:2059-2302