Publications
111 results found
Vine AM, Heaps AG, Kaftantzi L, et al., 2004, The role of CTLs in persistent viral infection:: Cytolytic gene expression in CD8<SUP>+</SUP> lymphocytes distinguishes between individuals with a high or low proviral load of human T cell lymphotropic virus type 1, JOURNAL OF IMMUNOLOGY, Vol: 173, Pages: 5121-5129, ISSN: 0022-1767
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- Citations: 63
Goon PKC, Biancardi A, Fast N, et al., 2004, Human T cell lymphotropic virus (HTLV) type-1-specific CD8<SUP>+</SUP> T cells:: Frequency and immunodominance hierarchy, JOURNAL OF INFECTIOUS DISEASES, Vol: 189, Pages: 2294-2298, ISSN: 0022-1899
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- Citations: 68
Debacq C, Asquith B, Reichert M, et al., 2003, Reduced cell turnover in bovine leukemia virus-infected, persistently lymphocytotic cattle, JOURNAL OF VIROLOGY, Vol: 77, Pages: 13073-13083, ISSN: 0022-538X
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- Citations: 29
Macallan DC, Asquith B, Irvine AJ, et al., 2003, Measurement and modeling of human T cell kinetics (vol 33, pg 2316, 2003), EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 33, Pages: 2947-2947, ISSN: 0014-2980
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- Citations: 2
Macallan DC, Wallace DL, Irvine AJ, et al., 2003, Rapid turnover of T cells in acute infectious mononucleosis, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 33, Pages: 2655-2665, ISSN: 0014-2980
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- Citations: 34
Goon PKC, Igakura T, Hanon E, et al., 2003, High circulating frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4<SUP>+</SUP> T cells in patients with HTLV-1-associated neurological disease, JOURNAL OF VIROLOGY, Vol: 77, Pages: 9716-9722, ISSN: 0022-538X
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- Citations: 48
Asquith B, Bangham CRM, 2003, An introduction to lymphocyte and viral dynamics: the power and limitations of mathematical analysis, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 270, Pages: 1651-1657, ISSN: 0962-8452
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- Citations: 29
Macallan DC, Asquith B, Irvine AJ, et al., 2003, Measurement and modeling of human T cell kinetics, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 33, Pages: 2316-2326, ISSN: 0014-2980
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- Citations: 95
Asquith B, Bangham CRM, 2003, The dynamics of T-cell fratricide: application of a robust approach to mathematical modelling in immunology, JOURNAL OF THEORETICAL BIOLOGY, Vol: 222, Pages: 53-69, ISSN: 0022-5193
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- Citations: 32
Debacq C, Sanchez T, Asquith B, et al., 2003, Cell dynamics in animal models for HTLV., 11th International Conference on Human Retrovirology: HTLV and Related Viruses, Publisher: MARY ANN LIEBERT INC PUBL, Pages: S17-S18, ISSN: 0889-2229
Saito M, Hanada K, Kodama D, et al., 2003, Naturally occurring mutations of HTLV-1 proviral genome within HAM/TSP patients and asymptomatic carriers; Relationship between proviral load, host genotype and disease state., 11th International Conference on Human Retrovirology: HTLV and Related Viruses, Publisher: MARY ANN LIEBERT INC PUBL, Pages: S60-S60, ISSN: 0889-2229
Asquith BE, Mosley AJ, Goon PK, et al., 2003, Does the CTL response determine HTLV-I equilibrium proviral load?, 11th International Conference on Human Retrovirology: HTLV and Related Viruses, Publisher: MARY ANN LIEBERT INC PUBL, Pages: S38-S38, ISSN: 0889-2229
Asquith B, Debacq C, Macallan DC, et al., 2002, Lymphocyte kinetics: the interpretation of labelling data, TRENDS IN IMMUNOLOGY, Vol: 23, Pages: 596-601, ISSN: 1471-4906
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- Citations: 84
Debacq C, Asquith B, Kerkhofs P, et al., 2002, Increased cell proliferation, but not reduced cell death, induces lymphocytosis in bovine leukemia virus-infected sheep, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 99, Pages: 10048-10053, ISSN: 0027-8424
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- Citations: 41
Bangham CRM, Asquith B, 2001, Virus dynamics - Mathematical principles of immunology and virology, SCIENCE, Vol: 291, Pages: 992-992, ISSN: 0036-8075
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- Citations: 1
Asquith B, Bangham CRM, 2000, The role of cytotoxic T lymphocytes in human T-cell lymphotropic virus type 1 infection, JOURNAL OF THEORETICAL BIOLOGY, Vol: 207, Pages: 65-79, ISSN: 0022-5193
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- Citations: 26
Hanon E, Asquith RE, Taylor GP, et al., 2000, High frequency of viral protein expression in human T cell lymphotropic virus type 1-infected peripheral blood mononuclear cells, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 16, Pages: 1711-1715, ISSN: 0889-2229
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- Citations: 34
Hanon E, Stinchcombe JC, Saito M, et al., 2000, Fratricide among CD8<SUP>+</SUP> T lymphocytes naturally infected with human T cell lymphotropic virus type I, IMMUNITY, Vol: 13, Pages: 657-664, ISSN: 1074-7613
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- Citations: 141
Asquith B, Hanon E, Taylor GP, et al., 2000, Is human T-cell lymphotropic virus type I really silent?, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, Vol: 355, Pages: 1013-1019, ISSN: 0962-8436
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- Citations: 41
Hanon E, Stinchcombe JC, Saito M, et al., 2000, Fracticide among CD8<sup>+</sup> T lymphocytes naturally infected with human T cell lymphotropic virus type I, Immunity, Vol: 13, Pages: 657-664, ISSN: 1074-7613
Infection and gene expression by the human T lymphotropic virus type I (HTLV-I) in vivo have been thought to be confined to CD4+ T lymphocytes. We show here that, in natural HTLV-I infection, a significant proportion of CD8+ T lymphocytes are infected by HTLV-I. Interestingly, HTLV-I-specific but not Epstein-Barr virus-specific CD8+ T lymphocytes were shown to be infected. Furthermore, HTLV-I protein expression in naturally infected CD8+ T lymphocytes renders them susceptible to fratricide mediated by autologous HTLV-I-specific CD8+ T lymphocytes. Fratricide among virus-specific CTLs could impair the immune control of HTLV-I and possibly other lymphotropic viruses.
Asquith B, 1996, Non-commutative geometry and the strong force, PHYSICS LETTERS B, Vol: 366, Pages: 220-223, ISSN: 0370-2693
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- Citations: 10
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