Publications

BibTex format

@article{Ehsan:2019:10.1002/asia.201900224,
author = {Ehsan, M and Kumar, A and Mortensen, JS and Du, Y and Hariharan, P and Kumar, KK and Ha, B and Byrne, B and Guan, L and Kobilka, BK and Loland, CJ and Chae, PS},
doi = {10.1002/asia.201900224},
journal = {Chemistry: An Asian Journal},
pages = {1926--1931},
title = {Self-assembly behaviors of a penta-phenylene maltoside and its application for membrane protein study},
url = {http://dx.doi.org/10.1002/asia.201900224},
volume = {14},
year = {2019}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We prepared an amphiphile with a penta-phenylene lipophilic group and a branched trimaltoside head group. This new agent, designated penta-phenylene maltoside (PPM), showed a marked tendency to self-assembly into micelles via strong aromatic-aromatic interactions in aqueous media, as evidenced by 1 HNMR spectroscopy and fluorescence studies. When utilized for membrane protein studies, this new agent was superior to DDM, a gold standard conventional detergent, in stabilizing multiple proteins long term. The ability of this agent to form aromatic-aromatic interactions is likely responsible for enhanced protein stabilization when associated with a target membrane protein.
AU  - Ehsan,M
AU  - Kumar,A
AU  - Mortensen,JS
AU  - Du,Y
AU  - Hariharan,P
AU  - Kumar,KK
AU  - Ha,B
AU  - Byrne,B
AU  - Guan,L
AU  - Kobilka,BK
AU  - Loland,CJ
AU  - Chae,PS
DO  - 10.1002/asia.201900224
EP  - 1931
PY  - 2019///
SN  - 1861-471X
SP  - 1926
TI  - Self-assembly behaviors of a penta-phenylene maltoside and its application for membrane protein study
T2  - Chemistry: An Asian Journal
UR  - http://dx.doi.org/10.1002/asia.201900224
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30969484
UR  - http://hdl.handle.net/10044/1/76824
VL  - 14
ER  -

Download

ProfessorBernadetteByrne

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)