Imperial College London

Dr. Beth Holder

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Senior Lecturer in Maternal and Fetal Health



+44 (0)20 7594 1773b.holder Website




3 008Institute of Reproductive and Developmental BiologyHammersmith Campus





Dr. Beth Holder is a Senior Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB).

Beth's expertise is in extracellular vesicles, reproductive and neonatal immunology, and placental biology. She has two main research focuses:

(1) The investigation of bi-directional communication between maternal immune cells and the placenta via extracellular vesicles

(2) Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses



Pantazi P, Kaforou M, Tang Z, et al., 2022, Placental macrophage responses to viral and bacterial ligands and the influence of fetal sex, Iscience, Vol:25

Timms K, Holder B, Day A, et al., 2022, Watermelon-derived extracellular vesicles influence human ex vivo placental cell behavior by altering intestinal secretions, Molecular Nutrition and Food Research, Vol:66, ISSN:1613-4125, Pages:1-12

Skirrow H, Barnett S, Bell S, et al., 2022, Women's views and experiences of accessing pertussis vaccination in pregnancy and infant vaccinations during the COVID-19 pandemic: A multi-methods study in the UK, Vaccine, Vol:40, ISSN:0264-410X, Pages:4942-4954

Maertens K, Leuridan E, Munoz FM, et al., 2022, Impact of vaccination during pregnancy on infants' immune responses to vaccinations- definitions and statistical approaches., Vaccine, Vol:40, Pages:4292-4295

Taylor SA, Sharma S, Remmel CAL, et al., 2022, HIV-Associated Alterations of the Biophysical Features of Maternal Antibodies Correlate With Their Reduced Transfer Across the Placenta, Journal of Infectious Diseases, Vol:226, ISSN:0022-1899, Pages:1441-1450

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