Imperial College London

Dr. Beth Holder

Faculty of MedicineDepartment of Surgery & Cancer

Lecturer in Maternal and Fetal Health



+44 (0)20 7594 2163b.holder




3 008Institute of Reproductive and Developmental BiologyHammersmith Campus





Dr. Beth Holder is a Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB).

Beth's expertise is in extracellular vesicles, reproductive and neonatal immunology, and placental biology. She has two main research focuses:

(1) The investigation of bi-directional communication between maternal immune cells and the placenta via extracellular vesicles, including exosomes

(2) Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses



Zhong Z, Haltalli M, Holder B, et al., 2018, The impact of timing of maternal influenza immunization on infant antibody levels at birth., Clin Exp Immunol

Rice TF, Donaldson B, Bouqueau M, et al., 2018, Macrophage- but not monocyte-derived extracellular vesicles induce placental pro-inflammatory responses, Placenta, Vol:69, ISSN:0143-4004, Pages:92-95

Le Doare K, Holder B, Bassett A, et al., 2018, Mother’s milk: A purposeful contribution to the development of the infant microbiota and immunity, Frontiers in Immunology, Vol:9, ISSN:1664-3224

Szymula A, Palermo RD, Bayoumy A, et al., 2018, Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome, Plos Pathogens, Vol:14, ISSN:1553-7366

Wilcox CR, Holder B, Jones CE, 2017, Factors Affecting the FcRn-Mediated Transplacental Transfer of Antibodies and implications for vaccination in Pregnancy, Frontiers in Immunology, Vol:8, ISSN:1664-3224

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