Imperial College London

Dr. Beth Holder

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Lecturer in Maternal and Fetal Health



+44 (0)20 7594 1773b.holder Website




3 008Institute of Reproductive and Developmental BiologyHammersmith Campus





Dr. Beth Holder is a Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB).

Beth's expertise is in extracellular vesicles, reproductive and neonatal immunology, and placental biology. She has two main research focuses:

(1) The investigation of bi-directional communication between maternal immune cells and the placenta via extracellular vesicles, including exosomes

(2) Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses



Skirrow H, Holder B, Meinel A, et al., 2021, Evaluation of a midwife-led, hospital based vaccination service for pregnant women, Human Vaccines and Immunotherapeutics, Vol:17, ISSN:1554-8600, Pages:237-246

Clements T, Rice T, Vamvakas G, et al., 2020, Update on trans-placental transfer of IgG subclasses: impact of maternal and fetal factors, Frontiers in Immunology, Vol:11, ISSN:1664-3224, Pages:1-17

Basu Roy R, Sambou B, Sissoko M, et al., 2020, Protection against mycobacterial infection: A case-control study of mycobacterial immune responses in pairs of Gambian children with discordant infection status despite matched TB exposure, Ebiomedicine, Vol:59, ISSN:2352-3964, Pages:1-10

Rice T, Holder E, Kampmann B, 2020, Antibody glycosylation in pregnancy and in newborns: biological roles and implications, Current Opinion in Infectious Diseases, Vol:33, ISSN:0951-7375, Pages:225-230

Rice T, Diavatopoulos D, Smits G, et al., 2019, Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK, Clinical and Experimental Immunology, Vol:197, ISSN:1365-2249, Pages:1-10

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