Imperial College London

Dr. Beth Holder

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Senior Lecturer in Maternal and Fetal Health



+44 (0)20 7594 1773b.holder Website




3 008Institute of Reproductive and Developmental BiologyHammersmith Campus





Dr. Beth Holder is a Senior Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB).

Beth's expertise is in extracellular vesicles, reproductive and neonatal immunology, and placental biology. She has two main research focuses:

(1) The investigation of bi-directional communication between maternal immune cells and the placenta via extracellular vesicles

(2) Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses



Swieboda D, Thwaites R, Rice T, et al., 2023, Natural killer cells and innate lymphoid cells but not NKT cells are mature in their cytokine production at birth, Clinical and Experimental Immunology, ISSN:0009-9104

Pantazi P, Kaforou M, Tang Z, et al., 2022, Placental macrophage responses to viral and bacterial ligands and the influence of fetal sex, Iscience, Vol:25

Pantazi P, Clements T, Veno M, et al., 2022, Distinct non-coding RNA cargo of extracellular vesicles from M1 and M2 human primary macrophages, Journal of Extracellular Vesicles, Vol:11, ISSN:2001-3078, Pages:1-19

Timms K, Holder B, Day A, et al., 2022, Watermelon-derived extracellular vesicles influence human ex vivo placental cell behavior by altering intestinal secretions, Molecular Nutrition and Food Research, Vol:66, ISSN:1613-4125, Pages:1-12

Skirrow H, Barnett S, Bell S, et al., 2022, Women's views and experiences of accessing pertussis vaccination in pregnancy and infant vaccinations during the COVID-19 pandemic: A multi-methods study in the UK, Vaccine, Vol:40, ISSN:0264-410X, Pages:4942-4954

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