Imperial College London

Dr. Beth Holder

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Lecturer in Maternal and Fetal Health



+44 (0)20 7594 1773b.holder Website




3 008Institute of Reproductive and Developmental BiologyHammersmith Campus





Dr. Beth Holder is a Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB).

Beth's expertise is in extracellular vesicles, reproductive and neonatal immunology, and placental biology. She has two main research focuses:

(1) The investigation of bi-directional communication between maternal immune cells and the placenta via extracellular vesicles, including exosomes

(2) Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses



Rice T, Holder E, Kampmann B, 2020, Antibody glycosylation in pregnancy and in newborns: biological roles and implications, Current Opinion in Infectious Diseases, Vol:33, ISSN:0951-7375, Pages:225-230

Rice T, Diavatopoulos D, Smits G, et al., 2019, Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK, Clinical and Experimental Immunology, Vol:197, ISSN:1365-2249, Pages:1-10

Szymula A, Palermo RD, Bayoumy A, et al., 2019, Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome (vol 14, e1006890, 2018), Plos Pathogens, Vol:15, ISSN:1553-7366

Zhong Z, Haltalli M, Holder B, et al., 2019, The impact of timing of maternal influenza immunisation on infant antibody levels at birth., Clinical and Experimental Immunology, Vol:195, ISSN:1365-2249, Pages:139-152

Thery C, Witwer KW, Aikawa E, et al., 2018, Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines, Journal of Extracellular Vesicles, Vol:7, ISSN:2001-3078

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