Imperial College London
Alternate

DrBeatrizJimenez

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

NMR Manager
 
 
 
//

Contact

 

+44 (0)20 7594 2441b.jimenez Website

 
 
//

Location

 

E306Burlington DanesHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@inbook{Jiménez:2016:10.1016/B978-0-12-409547-2.12122-5,
author = {Jiménez, B and MacIntyre, D},
booktitle = {Encyclopedia of Spectroscopy and Spectrometry},
doi = {10.1016/B978-0-12-409547-2.12122-5},
pages = {140--145},
title = {NMR metabolic phenotyping in clinical studies},
url = {http://dx.doi.org/10.1016/B978-0-12-409547-2.12122-5},
year = {2016}
}
Download

RIS format (EndNote, RefMan)

TY  - CHAP
AB  - Metabolic phenotyping comprises the determination of the metabolic signatures of biofluids and tissues. Differences in such metabolic profiles permit the stratification of individuals according to underlying biochemical status. This information allows objective assessment of health status including disease risk, diagnosis and prognosis, treatment response, drug metabolism, and toxicity. A key analytical platform used for metabolic phenotyping is nuclear magnetic resonance (NMR) spectroscopy due to its robustness, reproducibility, inherent quantitative nature, and capacity to be automated for high throughput. In this article, the main challenges faced in NMR-based metabolic phenotyping studies are explored and the role of phenome centers in the translation of NMR spectroscopy to clinical settings is described.
AU  - Jiménez,B
AU  - MacIntyre,D
DO  - 10.1016/B978-0-12-409547-2.12122-5
EP  - 145
PY  - 2016///
SN  - 9780128032244
SP  - 140
TI  - NMR metabolic phenotyping in clinical studies
T1  - Encyclopedia of Spectroscopy and Spectrometry
UR  - http://dx.doi.org/10.1016/B978-0-12-409547-2.12122-5
ER  -
Download