Imperial College London
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Dr Benjamin Mullish

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

IPPRF Research Fellow
 
 
 
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Contact

 

b.mullish

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Allegretti:2019:10.1016/S0140-6736(19)31266-8,
author = {Allegretti, JR and Mullish, BH and Kelly, C and Fischer, M},
doi = {10.1016/S0140-6736(19)31266-8},
journal = {Lancet},
pages = {420--431},
title = {The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications.},
url = {http://dx.doi.org/10.1016/S0140-6736(19)31266-8},
volume = {394},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Developments in high-throughput microbial genomic sequencing and other systems biology techniques have given novel insight into the potential contribution of the gut microbiota to health and disease. As a result, an increasing number of diseases have been characterised by distinctive changes in the composition and functionality of the gut microbiota; however, whether such changes are cause, consequence, or incidental to the disease in question remains largely uncertain. Restoration of the gut microbiota to a premorbid state is a key novel therapeutic approach of interest, and faecal microbiota transplantation-the transfer of prescreened stool from healthy donors into the gastrointestinal tract of patients-is gaining increasing importance in both the clinical and research settings. At present, faecal microbiota transplantation is only recommended in the treatment of recurrent Clostridioides difficile infection, although a large number of trials are ongoing worldwide exploring other potential therapeutic indications.
AU  - Allegretti,JR
AU  - Mullish,BH
AU  - Kelly,C
AU  - Fischer,M
DO  - 10.1016/S0140-6736(19)31266-8
EP  - 431
PY  - 2019///
SP  - 420
TI  - The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications.
T2  - Lancet
UR  - http://dx.doi.org/10.1016/S0140-6736(19)31266-8
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31379333
UR  - http://hdl.handle.net/10044/1/70605
VL  - 394
ER  -
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