Imperial College London

DrBarbaraMulloy

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Visiting Professor
 
 
 
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Contact

 

b.mulloy Website

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mulloy:2015:10.1007/978-1-4939-1714-3_11,
author = {Mulloy, B and Hogwood, J},
doi = {10.1007/978-1-4939-1714-3_11},
journal = {Methods Mol Biol},
pages = {105--118},
title = {Chromatographic molecular weight measurements for heparin, its fragments and fractions, and other glycosaminoglycans.},
url = {http://dx.doi.org/10.1007/978-1-4939-1714-3_11},
volume = {1229},
year = {2015}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Glycosaminoglycan samples are usually polydisperse, consisting of molecules with differing length and differing sequence. Methods for measuring the molecular weight of heparin have been developed to assure the quality and consistency of heparin products for medicinal use, and these methods can be applied in other laboratory contexts. In the method described here, high-performance gel permeation chromatography is calibrated using appropriate heparin molecular weight markers or a single broad standard calibrant, and used to characterize the molecular weight distribution of polydisperse samples or the peak molecular weight of monodisperse, or approximately monodisperse, heparin fractions. The same technology can be adapted for use with other glycosaminoglycans.
AU - Mulloy,B
AU - Hogwood,J
DO - 10.1007/978-1-4939-1714-3_11
EP - 118
PY - 2015///
SP - 105
TI - Chromatographic molecular weight measurements for heparin, its fragments and fractions, and other glycosaminoglycans.
T2 - Methods Mol Biol
UR - http://dx.doi.org/10.1007/978-1-4939-1714-3_11
UR - https://www.ncbi.nlm.nih.gov/pubmed/25325948
VL - 1229
ER -