Clinical and Academic Acitivities
Consultant Clinical Scientist in Clinical Biochemistry
Director of Supraregional Trace Element Laboratory (Imperial College Healthcare NHS Trust)
Applications of Inductively Coupled Plasma Mass Spectrometry (ICPMS) for analysis of trace elements in clinical samples.
Trace element metabolism.
Use of laser ablation ICPMS for study of tissue distribution of trace elements.
Current research topics and collaborations
Copper metabolism in Parkinson's Disease using stable isotopes. With Peter Bain (Neurosciences) and Mark Rehkamper (Earth Sciences).
Wear products from surgical implants. With Alister Hart (UCH, Royal National Orthopaedic Hospital), Fred Mosselamans (Diamond Light Source).
Selenium metabolism in renal disease, with Andrew Frankel (Renal Medicine).
Trace Element Specialist Advisory Group (UKNEQAS)
Clinical Reference Material User Group (LGC)
et al., 2019, Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide-induced hyponatremia, Kidney International Reports, Vol:4, ISSN:2468-0249, Pages:139-147
et al., 2017, Synchrotron analysis of human organ tissue exposed to implant material., Journal of Trace Elements in Medicine and Biology, Vol:46, ISSN:0946-672X, Pages:128-137
et al., 2016, Safety of long-term restrictive diets for peroxisomal disorders: vitamin and trace element status of patients treated for Adult Refsum Disease, International Journal of Clinical Practice, Vol:70, ISSN:1368-5031, Pages:229-235
et al., 2015, Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells, Scientific Reports, Vol:5, ISSN:2045-2322
et al., 2015, Copper, selenium and zinc levels after bariatric surgery in patients recommended to take multivitamin-mineral supplementation, Journal of Trace Elements in Medicine and Biology, Vol:31, ISSN:0946-672X, Pages:167-172