Imperial College London

DrBenjaminLamb

Faculty of MedicineDepartment of Surgery & Cancer

Honorary Clinical Research Fellow
 
 
 
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benjamin.lamb

 
 
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Medical SchoolSt Mary's Campus

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Summary

 

Publications

Publication Type
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166 results found

Pandiaraja M, Pryle I, West L, Gardner L, Shallcross O, Tay J, Shah N, Gnanapragasam V, Lamb BWet al., 2023, Utilisation and impact of predict prostate on decision‐making among clinicians and patients in a specialist tertiary referral centre: A retrospective cohort study, BJUI Compass, ISSN: 2688-4526

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Patients with intermediate‐risk prostate cancer are faced with the decision of whether to undergo radical treatment. Decision‐making aids, such as Predict Prostate, can empower both clinicians and patients to make treatment decisions with personalised information, but their impact on multi‐disciplinary team (MDT) decision‐making and uptake of radical treatment remains unknown.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>The objective of this study is to assess the utilisation and utility of Predict Prostate in informing treatment decisions for patients with intermediate‐risk prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>Patients and Methods</jats:title><jats:p>A retrospective cohort study was conducted in Cambridge University Hospitals (CUH) of patients referred to the prostate cancer specialist multi‐disciplinary team (pcSMDT) and robotic prostatectomy clinic (ROPD) between September 2019 and August 2021 for consideration of radical prostatectomy (RARP). Data on patient characteristics, use of PredictProstate and management decisions were collected from the Epic electronic medical record (EMR) of 839 patients, of whom 386 had intermediate‐risk prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The use of Predict Prostate at the pcSMDT increased in the second half of the study period (34.5% vs. 23.8%, <jats:italic>p</jats:italic> &lt; 0.001). The use of Predict Prostate was associated with an increased likelihood of attending ROPD for men with CPG2 prostate cancer (OR = 2.155, 95% CI = 1.158–4.013, <jats:italic>p</jats:italic> = 0.015) but a reduced likelihood of proceeding with RARP for

Journal article

Hussein H, Maitra N, Tay LJ, Saxionis I, Makin R, Sivathasan S, Smart S, Warren A, Shah N, Lamb BWet al., 2023, Analysis of the learning curve for Retzius-sparing robot-assisted radical prostatectomy for a single surgeon, Journal of Clinical Urology, ISSN: 2051-4158

<jats:sec><jats:title>Background:</jats:title><jats:p> The learning curve for Retzius-sparing robotic radical prostatectomy is not fully understood. </jats:p></jats:sec><jats:sec><jats:title>Objective:</jats:title><jats:p> This study attempts to identify the learning curve across the first 130 cases of a single surgeon. </jats:p></jats:sec><jats:sec><jats:title>Design, Setting and Participants:</jats:title><jats:p> All Retzius-sparing robotic radical prostatectomy cases performed by a single surgeon at a high-volume tertiary hospital between April 2019 and July 2022 were included. </jats:p></jats:sec><jats:sec><jats:title>Outcome Measurements and Statistical Analysis:</jats:title><jats:p> Outcome measures included positive surgical margin rate, complication rates and unplanned readmission to hospital, postoperative urinary continence, erectile function and prostate-specific antigen (PSA) measurement. Cases were divided chronologically into three groups and differences between groups assessed. </jats:p></jats:sec><jats:sec><jats:title>Results and Limitation:</jats:title><jats:p> A total of 130 Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) cases were identified. Differences were found between groups in several areas. Positive surgical margin rate fell between Group 1 (30.2%) and Group 3 (9.1%). Safety, postoperative continence, erectile function and PSA remained stable. Median patient age increased between Group 1 (59 years) and Group 3 (66.5 years) ( p = 0.04). Proportion of patients with stage &gt;T2 increased between Group 1 (27.9%) and Group 2 (41.9%) ( p = 0.036). Median console time increased between Group 1 (120 minutes) and Group 2 (150 minutes) ( p = 0.01). Median gland weight increased between Group 1 (2

Journal article

Tay LJ, Gillangullari K, Maitra N, Samson L, Patil V, Lamb BW, Shah Net al., 2023, Short (23-hour)-stay robotic-assisted radical prostatectomy in a state-funded national health service - Is it safe and feasible?, JOURNAL OF CLINICAL UROLOGY, ISSN: 2051-4158

Journal article

Soukup T, Lamb BW, Green JSA, Sevdalis N, Murtagh Get al., 2023, Analysis of communication styles underpinning clinical decision-making in cancer multidisciplinary team meetings, Frontiers in Psychology, Vol: 14, Pages: 1-13, ISSN: 1664-1078

INTRODUCTION: In cancer care, multidisciplinary team (MDT) meetings are the gold standard. While they are trying to maximize productivity on the back of the steadily increasing workload, growing cancer incidence, financial constraints, and staff shortages, concerns have been raised with regards to the quality of team output, as reported by Cancer Research UK in 2017: "Sometimes we discuss up to 70 patients. This is after a whole day of clinics, and we do not finish until after 19.00. Would you want to be number 70?". This study aimed to explore systematically some of the dynamics of group interaction and teamwork in MDT meetings. MATERIALS AND METHODS: This was a prospective observational study conducted across three MDTs/university hospitals in the United Kingdom. We video-recorded 30 weekly meetings where 822 patient cases were reviewed. A cross-section of the recordings was transcribed using the Jefferson notation system and analyzed using frequency counts (quantitative) and some principles of conversation analysis (qualitative). RESULTS: We found that, across teams, surgeons were the most frequent initiators and responders of interactional sequences, speaking on average 47% of the time during case discussions. Cancer nurse specialists and coordinators were the least frequent initiators, with the former speaking 4% of the time and the latter speaking 1% of the time. We also found that the meetings had high levels of interactivity, with an initiator-responder ratio of 1:1.63, meaning that for every sequence of interactions initiated, the initiator received more than a single response. Lastly, we found that verbal dysfluencies (laughter, interruptions, and incomplete sentences) were more common in the second half of meetings, where a 45% increase in their frequency was observed. DISCUSSION: Our findings highlight the importance of teamwork in planning MDT meetings, particularly with regard to Cancer Research UK in 2017 cognitive load/fatigue and decision-

Journal article

Lamb BW, Linton KD, Narahari K, 2023, BAUS oncology guidance for implementing streamlining in cancer MDT meetings: Selecting standards of care and operational considerations, JOURNAL OF CLINICAL UROLOGY, ISSN: 2051-4158

Journal article

Soukup T, Winters D, Chua K-C, Rowland P, Moneke J, Skolarus TA, Bharathan R, Harling L, Bali A, Asher V, Gandamihardja T, Sevdalis N, Green JSA, Lamb BWet al., 2023, Evaluation of changes to work patterns in multidisciplinary cancer team meetings due to the COVID-19 pandemic: A national mixed-method survey study, Cancer Medicine, Vol: 12, Pages: 8729-8741, ISSN: 2045-7634

BackgroundIt is not well understood the overall changes that multidisciplinary teams (MDTs) have had to make in response to the COVID-19 pandemic, nor the impact that such changes, in addition to the other challenges faced by MDTs, have had on decision-making, communication, or participation in the context of MDT meetings specifically.MethodsThis was a mixed method, prospective cross-sectional survey study taking place in the United Kingdom between September 2020 and August 2021.ResultsThe participants were 423 MDT members. Qualitative findings revealed hybrid working and possibility of virtual attendance as the change introduced because of COVID-19 that MDTs would like to maintain. However, IT-related issues, slower meetings, longer lists and delays were identified as common with improving of the IT infrastructure necessary going forward. In contrast, virtual meetings and increased attendance/availability of clinicians were highlighted as the positive outcomes resulting from the change. Quantitative findings showed significant improvement from before COVID-19 for MDT meeting organisation and logistics (M = 45, SD = 20) compared to the access (M = 50, SD = 12, t(390) = 5.028, p = 0.001), case discussions (M = 50, SD = 14, t(373) = −5.104, p = 0.001), and patient representation (M = 50, SD = 12, t(382) = −4.537, p = 0.001) at MDT meetings.DiscussionOur study explored the perception of change since COVID-19 among cancer MDTs using mixed methods. While hybrid working was preferred, challenges exist. Significant improvements in the meeting organisation and logistics were reported. Although we found no significant perceived worsening across the four domains investigated, there was an indication in this direction for the case discussions warranting further ‘live’ assessments of MDT meetings.

Journal article

Gao C, Peters M, Kurver P, Anbarasan T, Jayaraajan K, Manning T, Cashman S, Nambiar A, Cumberbatch M, Lamb BW, Pickard R, Erotocritou P, Smith D, Kasivisvanathan V, Shah TTet al., 2022, Nomogram predicting the probability of spontaneous stone passage in patients presenting with acute ureteric colic, BJU INTERNATIONAL, Vol: 130, Pages: 823-831, ISSN: 1464-4096

Journal article

Hilbert R, Bibby L, Boxall N, Srinivasan L, Aho T, Lamb BWet al., 2022, Anticoagulant but not antiplatelet use is associated with haematuria complications after bladder outflow surgery, JOURNAL OF CLINICAL UROLOGY, ISSN: 2051-4158

Journal article

Pandiaraja M, Pryle I, West L, Gardner L, Shallcross O, Tay J, Shah N, Gnanapragasam V, Lamb BWet al., 2022, 181 Service Evaluation of the Utilisation and Impact of PredictProstate on Clinical Decision-Making in a Prostate Cancer Specialist Multidisciplinary Service, Publisher: OXFORD UNIV PRESS, ISSN: 0007-1323

Conference paper

Fricker M, Nathan A, Georgi M, Patel S, Kien MK, Asif A, Sinha A, Mullins W, Shea J, Hanna N, Monks M, Peprah D, Sharma A, Ninkovic-Hall G, Lamb B, Kelly J, Sridhar A, Collins Jet al., 2022, 158 Virtual Interactive Surgical Skills Classroom: A Parallel-Designed, Non-Inferiority, Adjudicator-Blinded, Randomised Controlled Trial (VIRTUAL), Publisher: OXFORD UNIV PRESS, ISSN: 0007-1323

Conference paper

Stewart GD, Klatte T, Cosmai L, Bex A, Lamb BW, Moch H, Sala E, Siva S, Porta C, Gallieni Met al., 2022, The multispeciality approach to the management of localised kidney cancer, LANCET, Vol: 400, Pages: 523-534, ISSN: 0140-6736

Journal article

Hitz F, Ribi K, Grote G, Kolbe M, Schmitz C, Lamb BW, Ruhstaller T, Berchtold P, Sevdalis Net al., 2022, Team functioning across different tumour types: Insights from a Swiss cancer center using qualitative and quantitative methods, CANCER REPORTS, Vol: 5

Journal article

Caglic I, Sushentsev N, Shah N, Warren AY, Lamb BW, Barrett Tet al., 2022, Integration of Prostate Biopsy Results with Pre-Biopsy Multiparametric Magnetic Resonance Imaging Findings Improves Local Staging of Prostate Cancer, CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES, Vol: 73, Pages: 515-523, ISSN: 0846-5371

Journal article

Soukup T, Lamb BW, Morbi A, Shah NJ, Bali A, Asher V, Gandamihardja T, Giordano P, Darzi A, Sevdalis N, Green JSAet al., 2022, Cancer multidisciplinary team meetings: impact of logistical challenges on communication and decision-making, BJS OPEN, Vol: 6, ISSN: 2474-9842

Journal article

Sivathasan S, Patel KM, Smart S, Nathan A, Warren A, Shah N, Lamb BWet al., 2022, Incremental modification of robotic prostatectomy technique can lead to aggregated marginal gains to significantly improve functional outcomes without compromising oncological control, JOURNAL OF ROBOTIC SURGERY, Vol: 16, Pages: 665-675, ISSN: 1863-2483

Journal article

Harris J, Beck S, Ayers N, Bick D, Lamb BW, Aref-Adib M, Kelly T, Green JSA, Taylor Cet al., 2022, Improving teamwork in maternity services: A rapid review of interventions, MIDWIFERY, Vol: 108, ISSN: 0266-6138

Journal article

Caglic I, Sushentsev N, Colarieti A, Warren AY, Shah N, Lamb BW, Barrett Tet al., 2022, Value of the capsular enhancement sign on dynamic contrast-enhanced prostate multiparametric MRI for the detection of extracapsular extension, EUROPEAN JOURNAL OF RADIOLOGY, Vol: 150, ISSN: 0720-048X

Journal article

Sajjad W, Thankappannair V, Shah S, Ahmed A, Saeb-Parsy K, Kastner C, Lamb B, Gnanapragasam VJet al., 2022, Diagnostic value of the abnormal digital rectal examination in the modern MRI-based prostate cancer diagnostic pathway, JOURNAL OF CLINICAL UROLOGY, ISSN: 2051-4158

Journal article

Adamina M, Ademuyiwa A, Adisa A, Bhangu AA, Bravo AM, Cunha MF, Emile S, Ghosh D, Glasbey JC, Harris B, Keller D, Lawday S, Lederhuber H, Leventoglu S, Li E, Modolo MM, Mittal R, Mohan HM, Nepogodiev D, Parreno-Sacdalan MD, Pata F, Pockney P, Rutegard M, Simoes JFF, Smart N, Varghese C, Siaw-Acheampong K, Benson RA, Bywater E, Chaudhry D, Dawson BE, Evans JP, Gujjuri RR, Heritage E, Jones CS, Kamarajah SK, Khatri C, Khaw RA, Keatley JM, Knight A, Smart NJ, Minaya-Bravo A, Gallo G, Moug S, Di Saverio S, Vallance A, Vimalchandra D, Griffiths EA, Evans RPT, Townen P, Roberts K, McKay S, Isaac J, Satoi S, Edwards J, Coonar AS, Marchbank A, Caruana EJ, Layton GR, Patel A, Brunelli A, Ford S, Desai A, Gronchi A, Fiore M, Almond M, Tirotta F, Dumitra S, Kolias A, Price SJ, Fountain DM, Jenkinson MD, Hutchinson P, Marcus HJ, Piper RJ, Lippa L, Servadei F, Esene I, Freyschlag C, Neville I, Rosseau G, Schaller K, Demetriades AK, Robertson F, Alamri A, Shaw R, Schache AG, Winter SC, Ho M, Nankivell P, Biel JR, Batstone M, Ganly I, Vidya R, Wilkins A, Singh JK, Thekinkattil D, Sundar S, Fotopoulou C, Leung EY, Khan T, Chiva L, Sehouli J, Fagotti A, Cohen P, Gutelkin M, Ghebre R, Konney T, Pareja R, Bristow R, Dowdy S, Shylasree TS, Seenivasagam RK, Ng J, Fujiwar K, Stewart GD, Lamb B, Narahari K, McNeill A, Colquhoun A, McGrath JS, Bromage S, Barod R, Kasivisvanathan V, Klatte T, Abbott TEF, Abukhalaf S, Ademuyiwa AO, Agarwal A, Akkulak M, Alameer E, Alderson D, Alakaloko F, Albertsmeier M, Alser O, Alshaar M, Alshryda S, Arnaud AP, Augestad KM, Ayasra F, Azevedo J, Bankhead-Kendall BK, Barlow E, Beard D, Blanco-Colino R, Brar A, Breen KA, Bretherton C, Buarque IL, Burke J, Chaar M, Chakrabortee S, Christensen P, Cox D, Cukier M, Davidson GH, Drake TM, Edwards JG, Elhadi M, Farik S, Fitzgerald JE, Garmanova T, Gomes GMA, Grecinos G, Gruendl M, Halkias C, Harrison EM, Hisham I, Hutchinson PJ, Hwang S, Isik A, Jonker P, Kaafarani HMA, Kruijff S, Lawani I, Litvin A, Loehrer A, Lofet al., 2022, The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study, Colorectal Disease, Vol: 24, Pages: 708-726, ISSN: 1462-8910

AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January–April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90–1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69–1.27, P = 0.672). Longer delays were not associated with poorer outcomes.ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease.

Journal article

Sushentsev N, McLean MA, Warren AY, Benjamin AJV, Brodie C, Frary A, Gill AB, Jones J, Kaggie JD, Lamb BW, Locke MJ, Miller JL, Mills IG, Priest AN, Robb FJL, Shah N, Schulte RF, Graves MJ, Gnanapragasam VJ, Brindle KM, Barrett T, Gallagher FAet al., 2022, Hyperpolarised <SUP>13</SUP>C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer (vol 13, 466, 2022), NATURE COMMUNICATIONS, Vol: 13

Journal article

Miah S, Maw J, Pang K, Nair V, Hori S, Lamb A, Martin A, Bratt O, Lamb B, Shah Net al., 2022, The provision of prostate cancer patient information leaflets on an electronic tablet: A further step to paperless health-care provision, UROLOGY ANNALS, Vol: 14, Pages: 156-161, ISSN: 0974-7796

Journal article

Pryle I, Pandiaraja M, West L, Gardener L, Shallcross O, Tay J, Shah N, Gnanapragasam V, Lamb BWet al., 2022, Service evaluation of the utilisation and impact of PredictProstate on clinical decision-making in a prostate cancer specialist multidisciplinary service, Publisher: ELSEVIER, Pages: S1660-S1662, ISSN: 0302-2838

Conference paper

Sushentsev N, McLean MA, Warren AY, Benjamin AJ, Brodie C, Frary A, Gill AB, Jones J, Kaggie JD, Lamb BW, Locke MJ, Miller JL, Mills IG, Priest AN, Robb FJL, Shah N, Schulte RS, Graves MJ, Gnanapragasam VJ, Brindle KM, Barrett T, Gallagher FAet al., 2022, Hyperpolarised <SUP>13</SUP>C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer, NATURE COMMUNICATIONS, Vol: 13

Journal article

Robertson-Waters E, Donaldson C, Light A, Lamb B, Thiruchelvam Net al., 2022, Guidance for diagnosis and management of bladder injuries - is practice up to date? Comment, BJU INTERNATIONAL, Vol: 129, Pages: 25-27, ISSN: 1464-4096

Journal article

Nathan A, Hanna N, Rashid A, Patel S, Phuah Y, Flora K, Fricker M, Cleaveland P, Kasivisvanathan V, Williams N, Miah S, Collins J, Kelkar A, Sridhar A, Hines J, Briggs T, Kelly J, Shah N, Shaw G, Sooriakumaran P, Rajan P, Lamb BW, Nathan Set al., 2021, New recommendations to reduce unnecessary blood tests after robot-assisted radical prostatectomy, BJU INTERNATIONAL, Vol: 128, Pages: 681-684, ISSN: 1464-4096

Journal article

Nathan A, Fricker M, Georgi M, Patel S, Hang MK, Asif A, Sinha A, Mullins W, Shea J, Hanna N, Monks M, Peprah D, Sharma A, Ninkovic-Hall G, Lamb BW, Kelly J, Sridhar A, Collins JWet al., 2021, Virtual Interactive Surgical Skills Classroom: A Parallel-group, Non-inferiority, Adjudicator-blinded, Randomised Controlled Trial (VIRTUAL), JOURNAL OF SURGICAL EDUCATION, Vol: 79, Pages: 791-801, ISSN: 1931-7204

Journal article

Glasbey J, Ademuyiwa A, Adisa A, AlAmeer E, Arnaud AP, Ayasra F, Azevedo J, Minaya-Bravo A, Costas-Chavarri A, Edwards J, Elhadi M, Fiore M, Fotopoulou C, Gallo G, Ghosh D, Griffiths EA, Harrison E, Hutchinson P, Lawani I, Lawday S, Lederhuber H, Leventoglu S, Li E, Gomes GMA, Mann H, Marson EJ, Martin J, Mazingi D, McLean K, Modolo M, Moore R, Morton D, Ntirenganya F, Pata F, Picciochi M, Pockney P, Ramos-De la Medina A, Roberts K, Roslani AC, Kottayasamy Seenivasagam R, Shaw R, Simões JFF, Smart N, Stewart GD, Sullivan R, Sundar S, Tabiri S, Taylor EH, Vidya R, Nepogodiev D, Bhangu A, Glasbey JC, McLean K, Nepogodiev D, Harrison E, Bhangu AA, Nepogodiev D, Siaw-Acheampong K, Benson RA, Bywater E, Chaudhry D, Dawson BE, Evans JP, Glasbey JC, Gujjuri RR, Heritage E, Jones CS, Kamarajah SK, Khatri C, Khaw RA, Keatley JM, Knight A, Lawday S, Li E, Mann HS, Marson EJ, McLean KA, Mckay SC, Mills EC, Pellino G, Picciochi M, Taylor EH, Tiwari A, Simoes JFF, Trout IM, Venn ML, Wilkin RJW, Bhangu A, Glasbey JC, Smart NJ, Minaya-Bravo A, Evans JP, Gallo G, Moug S, Pata F, Pockney P, Di Saverio S, Vallance A, Vimalchandran D, Griffiths EA, Kamarajah SK, Evans RPT, Townend P, Roberts K, McKay S, Isaac J, Satoi S, Edwards J, Coonar AS, Marchbank A, Caruana EJ, Layton GR, Patel A, Brunelli A, Ford S, Desai A, Gronchi A, Fiore M, Almond M, Tirotta F, Dumitra S, Kolias A, Price SJ, Fountain DM, Jenkinson MD, Hutchinson P, Marcus HJ, Piper RJ, Lippa L, Servadei F, Esene I, Freyschlag C, Neville I, Rosseau G, Schaller K, Demetriades AK, Robertson F, Alamri A, Shaw R, Schache AG, Winter SC, Ho M, Nankivell P, Rey Biel J, Batstone M, Ganly I, Vidya R, Wilkins A, Singh JK, Thekinkattil D, Sundar S, Fotopoulou C, Leung EYL, Khan T, Chiva L, Sehouli J, Fagotti A, Cohen P, Gutelkin M, Ghebre R, Konney T, Pareja R, Bristow R, Dowdy S, Shylasree TS, Kottayasamy Seenivasagam R, Ng J, Fujiwara K, Stewart GD, Lamb B, Narahari K, McNeill A, Colquhoun A, McGrath JS, Bromage S, Barod R, Kasivisvaet al., 2021, Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study, The Lancet Oncology, Vol: 22, Pages: 1507-1517, ISSN: 1470-2045

BackgroundSurgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction.MethodsThis international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index <20), moderate lockdowns (20–60), and full lockdowns (>60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models were used to explore the associations between lockdowns and non-operation. Intervals from diagnosis to surgery were compared across COVID-19 government response index groups. This study was registered at ClinicalTrials.gov, NCT04384926.FindingsOf eligible patients awaiting surgery, 2003 (10·0%) of 20 006 did not receive surgery after a median follow-up of 23 weeks (IQR 16–30), all of whom had a COVID-19-related reason given for non-operation. Light restrictions were associated with a 0·6% non-operation rate (26 of 4521), moderate lockdowns with a 5·5% rate (201 of 3646; adjusted hazard ratio [HR] 0·81, 95% CI 0·77–0·84; p<0·0001), and full lockdowns with a 15·0% rate (1775 of 11 827; HR 0·51, 0·50–0·53; p<0·0001). In sensitivity analyses, including adjustment for SARS-CoV-2 case notif

Journal article

Lamb BW, Miah S, Soukup T, 2021, ASO Author Reflections: The Pursuit of Digitalised Quality Improvement Assessment Tools for Cancer Multidisciplinary Teams, ANNALS OF SURGICAL ONCOLOGY, Vol: 28, Pages: 7589-7590, ISSN: 1068-9265

Journal article

Lamb BW, Miah S, Skolarus TA, Stewart GD, Green JSA, Sevdalis N, Soukup Tet al., 2021, Development and Validation of a Short Version of the Metric for the Observation of Decision-Making in Multidisciplinary Tumor Boards: MODe-Lite, ANNALS OF SURGICAL ONCOLOGY, Vol: 28, Pages: 7577-7588, ISSN: 1068-9265

Journal article

Soukup T, Sevdalis N, Green JSA, Lamb BW, Chapman C, Skolarus TAet al., 2021, Making Tumor Boards More Patient-Centered: Let's Start With the Name, JCO ONCOLOGY PRACTICE, Vol: 17, Pages: 591-+, ISSN: 2688-1527

Journal article

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