Summary
I am a leading exponent internationally of the “Learning Health System’ (LHS) concept. Although my initial training in research was in heath technology assessment, real-world (pragmatic) clinical trials and clinical research in Family Medicine, since 2003 I have worked in the area of Clinical Informatics, being appointed to a Chair in Medical Informatics at Imperial in 2015 and elected one of the first 100 founding fellows of the new UK Faculty of Clinical Informatics in 2017. I have had wide exposure to European and US clinical informatics through workshops and symposia.
I was the UK lead investigator on an NIH Clinical Research Roadmap project (The Electronic Primary Care Research Network. HHS268N200425212C) 2006-10. From 2010-15 I led a €9million EU FP7 programme, ‘TRANSFoRm: Patient Safety and Translational Research in Europe’.
TRANSFoRm set about using ontologies, data standards and models to create a common infrastructure for the LHS with three specific use cases (eSource for clinical trials, phenomics and clinical diagnosis.
Prior to moving to Imperial I was Wolfson Professor of General Practice at King's College London. At Imperial, I work in the Institute of Global Health Innovation, with research in Artificial Intelligence, cancer diagnosis and learning systems, eSource for clinical trials and global eHealth. I sit on the Cancer Research UK Population research funding panel and the Medical Research Council Methodology Research panel.
Currently there are three areas of active research:
1. LHS and guidelines. Completing the LHS cycle with a computational infrastructure for deploying guidelines as decision support linked to the EHR. Currently supported as an EPSRC Global Health Development Project (www.ROAD2H.org).
2. Establishing a LHS for diagnosis. Currently moving from a prototype evaluated in a rich simulation to deployment in practices. Funded by CRUK.
3. Developing a clinical prediction rule for the risk of admission/death in acute Covid in Primary care. RECAP - funded by the Community Jameel Imperial College Covid-19 Excellence fund (and collaborating with Oxford University). RECAP
Publications
Journals
Delaney BC, Rayner C, Freyer A, et al. , 2022, Author response., Br J Gen Pract, Vol:72, Pages:259-260
Meza-Torres B, Delanerolle G, Okusi C, et al. , 2022, Differences in clinical presentation with long covid following community and hospital infection, and associations with all-cause mortality: English sentinel network database study., Jmir Public Health Surveill
Ward H, Flower B, Garcia PJ, et al. , 2021, Global surveillance, research, and collaboration needed to improve understanding and management of long COVID, The Lancet, Vol:398, ISSN:0140-6736, Pages:2057-2059
Hay AD, Moore M, Taylor J, et al. , 2021, Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT Introduction, Health Technology Assessment, Vol:25, ISSN:1366-5278, Pages:1-+