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@article{Bangham:2023:10.1182/blood.2022019332,
author = {Bangham, CRM},
doi = {10.1182/blood.2022019332},
journal = {Blood},
pages = {2299--2306},
title = {HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma},
url = {http://dx.doi.org/10.1182/blood.2022019332},
volume = {141},
year = {2023}
}

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TY  - JOUR
AB  - Human T-cell leukemia virus type 1 (HTLV-1), also known as human T-lymphotropic virus type 1, causes the aggressive malignancy known as adult T-cell leukemia/lymphoma (ATL) in 5% of infected people and a chronic progressive inflammatory disease of the central nervous system, HTLV-1–associated myelopathy, in ∼0.3% to 4% of them, varying between regions where it is endemic. Reliable treatments are lacking for both conditions, although there have been promising recent advances in the prevention and treatment of ATL. Because ATL typically develops after several decades of infection, it is necessary to understand how the virus persists in the host despite a strong immune response, and how this persistence results in oncogenesis.
AU  - Bangham,CRM
DO  - 10.1182/blood.2022019332
EP  - 2306
PY  - 2023///
SN  - 0006-4971
SP  - 2299
TI  - HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma
T2  - Blood
UR  - http://dx.doi.org/10.1182/blood.2022019332
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001001754700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://ashpublications.org/blood/article/141/19/2299/494602/HTLV-1-persistence-and-the-oncogenesis-of-adult-T
UR  - http://hdl.handle.net/10044/1/109366
VL  - 141
ER  -

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