Imperial College London

Professor Chris Braddock

Faculty of Natural SciencesDepartment of Chemistry

Professor of Organic Chemistry



+44 (0)20 7594 5772c.braddock




601EMolecular Sciences Research HubWhite City Campus





Chris Braddock read Chemistry at St Peter's College, Oxford and graduated with first class honours in 1992. He remained in Oxford to work with John Brown, FRS, for his doctorate which he obtained in January 1996. He was immediately appointed as a Fixed-Term Lecturer at Imperial College where he worked in Professor Tony Barrett's laboratories. In October 1998 he was appointed as a Lecturer in the newly created Synthesis section in the Department of Chemistry and initiated independent research.  He was promoted to Senior Lecturer in 2005, to Reader in 2008, and to Professor of Organic Chemistry in 2015.


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Selected Publications

Journal Articles

Braddock D, Rowley B, Lickiss P, et al., 2023, On the use of triarylsilanols as catalysts for direct amidation of carboxylic acids, Journal of Organic Chemistry, Vol:88, ISSN:0022-3263, Pages:9853-9869

Braddock D, Lancaster B, Tighe C, et al., 2023, Surmounting byproduct inhibition in an intermolecular catalytic asymmetric alkene bromoesterification reaction as revealed by kinetic profiling, Journal of Organic Chemistry, Vol:88, ISSN:0022-3263, Pages:8904-8914

Ciccarelli D, Christopher Braddock D, Surman AJ, et al., 2023, Enhanced selectivity for acidic contaminants in drinking water: From suspect screening to toxicity prediction, Journal of Hazardous Materials, Vol:448, ISSN:0304-3894, Pages:1-12

McCarthy S, Desaunay O, Lee Wei Jie A, et al., 2022, Homogeneous gold catalysis using complexes recovered from waste electronic equipment, Acs Sustainable Chemistry and Engineering, Vol:10, ISSN:2168-0485, Pages:15726-15734

Braddock D, Duran-Corbera A, Nilforoushan M, et al., 2022, (±)-Polysiphenol and other Analogues via Symmetrical Intermolecular Dimerizations: a Synthetic, Spectroscopic, Structural and Computational Study, Journal of Natural Products, Vol:85, ISSN:0163-3864, Pages:2650-2655

Braddock D, Limpaitoon N, Oliwa K, et al., 2022, A stereoselective hydride transfer reaction with contributions from attractive dispersion force control, Chemical Communications, Vol:58, ISSN:1359-7345, Pages:4981-4984

Braddock D, Davies J, Lickiss P, 2022, Methyltrimethoxysilane (MTM) as a reagent for direct amidation of carboxylic acids, Organic Letters, Vol:24, ISSN:1523-7052, Pages:1175-1179

McCarthy S, Braddock D, Wilton-Ely J, 2021, Strategies for sustainable palladium catalysis, Coordination Chemistry Reviews, Vol:442, ISSN:0010-8545, Pages:1-26

McCarthy S, Lee Wei Jie A, Braddock D, et al., 2021, From waste to green applications: the use of recovered gold and palladium in catalysis, Molecules, Vol:26, ISSN:1420-3049

Davies J, Braddock D, Lickiss P, 2021, Silicon compounds as stoichiometric coupling reagents for direct amidation, Organic & Biomolecular Chemistry, Vol:19, ISSN:1477-0520, Pages:6746-6760

Bahou K, Braddock D, Meyer A, et al., 2020, Relay cross metathesis for the iterative construction of terpenoids and synthesis of a diterpene benzoate macrolide of biogenetic relevance to the bromophycolides, Organic Letters, Vol:22, ISSN:1523-7052, Pages:3176-3179

Bahou K, Braddock D, Meyer A, et al., 2020, A relay strategy actuates pre-existing trisubstituted olefins in monoterpenoids for cross metathesis with trisubstituted alkenes, Journal of Organic Chemistry, Vol:85, ISSN:0022-3263, Pages:4906-4917

Braddock DC, Lickiss PD, Rowley BC, et al., 2018, Tetramethyl Orthosilicate (TMOS) as a Reagent for Direct Amidation of Carboxylic Acids, Organic Letters, Vol:20, ISSN:1523-7060, Pages:950-953

Bahou KA, Braddock DC, Meyer AG, et al., 2017, Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis, Organic Letters, Vol:19, ISSN:1523-7060, Pages:5332-5335

Clarke J, Bonney KJ, Yaqoob M, et al., 2016, Epimeric Face-Selective Oxidations and Diastereodivergent Transannular Oxonium Ion Formation Fragmentations: Computational Modeling and Total Syntheses of 12-Epoxyobtusallene IV, 12-Epoxyobtusallene II, Obtusallene X, Marilzabicycloallene C, and Marilzabicycloallene D, Journal of Organic Chemistry, Vol:81, ISSN:0022-3263, Pages:9539-9552

Braddock DC, Mahtey A, Rzepa HS, et al., 2016, Stable bromoallene oxides, Chemical Communications, Vol:52, ISSN:1364-548X, Pages:11219-11222

Braddock DC, Gao AX, White AJP, et al., 2014, Studies towards the synthesis of halomon: asymmetric hexafunctionalisation of myrcene, Chemical Communications, Vol:50, ISSN:1359-7345, Pages:13725-13728

Braddock DC, Sbircea D-T, 2014, Proof-of-principle direct double cyclisation of a linear C<sub>15</sub>-precursor to a dibrominated bicyclic medium-ring ether relevant to <i>Laurencia</i> species, Chemical Communications, Vol:50, ISSN:1359-7345, Pages:12691-12693

Braddock DC, Marklew JS, Foote KM, et al., 2013, An Enantiospecific Polyene Cyclization Initiated by an Enantiomerically Pure Bromonium Ion, Chirality, Vol:25, ISSN:0899-0042, Pages:692-700

Braddock DC, Clarke J, Rzepa HS, 2013, Epoxidation of bromoallenes connects red algae metabolites by an intersecting bromoallene oxide - Favorskii manifold, Chemical Communications, Vol:49, ISSN:1359-7345, Pages:11176-11178

Bonney KJ, Braddock DC, 2012, A Unifying Stereochemical Analysis for the Formation of Halogenated C<sub>15</sub>-Acetogenin Medium-Ring Ethers From <i>Laurencia</i> Species via Intramolecular Bromonium Ion Assisted Epoxide Ring-Opening and Experimental Corroboration with a Model Epoxide, Journal of Organic Chemistry, Vol:77, ISSN:0022-3263, Pages:9574-9584

Braddock DC, Roy D, Lenoir D, et al., 2012, Verification of stereospecific dyotropic racemisation of enantiopure D and L-1,2-dibromo-1,2-diphenylethane in non-polar media, Chemical Communications, Vol:48, ISSN:1359-7345, Pages:8943-8945

Bonney KJ, Braddock DC, White AJP, et al., 2011, Intramolecular Bromonium Ion Assisted Epoxide Ring-Opening: Capture of the Oxonium Ion with an Added External Nucleophile, Journal of Organic Chemistry, Vol:76, ISSN:0022-3263, Pages:97-104

Braddock DC, Marklew JS, Thomas AJF, 2011, Enantiospecific bromonium ion generation and intramolecular capture: a model system for asymmetric bromonium ion-induced polyene cyclisations, Chemical Communications, Vol:47, ISSN:1359-7345, Pages:9051-9053

Braddock DC, Pouwer RH, Burton JW, et al., 2009, Clarification of the Stereochemical Course of Nucleophilic Substitution of Arylsulfonate-Based Nucleophile Assisting Leaving Groups, Journal of Organic Chemistry, Vol:74, ISSN:0022-3263, Pages:6042-6049

Braddock DC, Millan DS, Perez-Fuertes Y, et al., 2009, Bromonium Ion Induced Transannular Oxonium Ion Formation-Fragmentation in Model Obtusallene Systems and Structural Reassignment of Obtusallenes V-VII, Journal of Organic Chemistry, Vol:74, ISSN:0022-3263, Pages:1835-1841

Braddock DC, Hermitage SA, Kwok L, et al., 2009, The generation and trapping of enantiopure bromonium ions, Chemical Communications, ISSN:1359-7345, Pages:1082-1084

Braddock DC, Rzepa HS, 2008, Structural reassignment of obtusallenes V, VI, and VII by GIAO-based density functional prediction, Journal of Natural Products, Vol:71, ISSN:0163-3864, Pages:728-730

Braddock DC, Bhuva R, Perez-Fuertes Y, et al., 2008, The stereochemical course of bromoetherification of enynes, Chemical Communications, ISSN:1359-7345, Pages:1419-1421

Braddock DC, Bhuva R, Millan DS, et al., 2007, A biosynthetically-inspired synthesis of the tetrahydrofuran core of obtusallenes II and IV, Organic Letters, Vol:9, ISSN:1523-7060, Pages:445-448

Braddock DC, 2006, A hypothesis concerning the biosynthesis of the obtusallene family of marine natural products via electrophilic bromination, Organic Letters, Vol:8, ISSN:1523-7060, Pages:6055-6058

Braddock DC, Cansell G, Hermitage SA, et al., 2006, Bromoiodinanes with an I(III)-Br bond: preparation, X-ray crystallography and reactivity as electrophilic brominating agents, Chemical Communications, ISSN:1359-7345, Pages:1442-1444

Braddock DC, Cansell G, Hermitage SA, et al., 2004, An asymmetric synthesis of enantiopure chair and twist <i>trans</i>-cyclooctene isomers, Tetrahedron-Asymmetry, Vol:15, ISSN:0957-4166, Pages:3123-3129

Braddock DC, MacGilp LD, Perry BG, 2002, Improved synthesis of (±)-4,12-dihydroxy[2.2]paracyclophane and its enantiomeric resolution by enzymatic methods:: Planar chiral (<i>R</i>)- and (<i>S</i>)-phanol, Journal of Organic Chemistry, Vol:67, ISSN:0022-3263, Pages:8679-8681

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