Imperial College London

DrCarolineColijn

Faculty of Natural SciencesDepartment of Mathematics

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 2647c.colijn Website

 
 
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Location

 

626Huxley BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

84 results found

Cohen T, Colijn C, Wright A, Zignol M, Pym A, Murray Met al., 2009, Does Current Drug Resistance Surveillance Provide Useful Information in Tuberculosis?, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, Pages: 82-83, ISSN: 1073-449X

JOURNAL ARTICLE

Cohen T, Dye C, Colijn C, Williams B, Murray Met al., 2009, Mathematical models of the epidemiology and control of drug-resistant TB., Expert Rev Respir Med, Vol: 3, Pages: 67-79

Recent reports of extensively drug-resistant TB in South Africa have renewed concerns that antibiotic resistance may undermine progress in TB control. We review three major questions for which mathematical models elucidate the epidemiology and control of drug-resistant TB. How is multiple drug-resistant Mycobacterium tuberculosis selected for in individuals exposed to combination chemotherapy? What factors determine the prevalence of drug-resistant TB? Which interventions to prevent the spread of drug-resistant TB are effective and feasible? Models offer insight into the acquisition and amplification of drug resistance, reveal the importance of distinguishing the intrinsic and extrinsic determinants of the reproductive capacity of drug-resistant M. tuberculosis, and demonstrate the cost effectiveness of interventions for drug-resistant TB. These models also highlight knowledge gaps for which new research will improve our ability to project trends of drug resistance and develop more effective policies for its control.

JOURNAL ARTICLE

Colijn C, 2009, Propagation through dynamic networks: degree distribution and the spread of disease, IEEE Information Theory Workshop (ITW), Publisher: IEEE, Pages: 594-598

CONFERENCE PAPER

Colijn C, Brandes A, Zucker J, Lun DS, Weiner B, Farhat MR, Cheng T-Y, Moody DB, Murray M, Galagan JEet al., 2009, Interpreting Expression Data with Metabolic Flux Models: Predicting Mycobacterium tuberculosis Mycolic Acid Production, PLOS COMPUTATIONAL BIOLOGY, Vol: 5, ISSN: 1553-734X

JOURNAL ARTICLE

Colijn C, Cohen T, Murray M, 2009, Latent Coinfection and the Maintenance of Strain Diversity, BULLETIN OF MATHEMATICAL BIOLOGY, Vol: 71, Pages: 247-263, ISSN: 0092-8240

JOURNAL ARTICLE

Lipsitch M, Colijn C, Cohen T, Hanage WP, Fraser Cet al., 2009, No coexistence for free: Neutral null models for multistrain pathogens, EPIDEMICS, Vol: 1, Pages: 2-13, ISSN: 1755-4365

JOURNAL ARTICLE

Cohen T, Colijn C, Finklea B, Wright A, Zignol M, Pym A, Murray Met al., 2008, Are Survey-Based Estimates of the Burden of Drug Resistant TB Too Low? Insight from a Simulation Study, PLOS ONE, Vol: 3, ISSN: 1932-6203

JOURNAL ARTICLE

Cohen T, Colijn C, Murray M, 2008, Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 105, Pages: 16302-16307, ISSN: 0027-8424

JOURNAL ARTICLE

Cohen T, Colijn C, Wright A, Zignol M, Pym A, Murray Met al., 2008, Challenges in estimating the total burden of drug-resistant tuberculosis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 177, Pages: 1302-1306, ISSN: 1073-449X

JOURNAL ARTICLE

Lin H-H, Murray M, Cohen T, Colijn C, Ezzati Met al., 2008, Effects of smoking and solid-fuel use on COPD, lung cancer, and tuberculosis in China: a time-based, multiple risk factor, modelling study, LANCET, Vol: 372, Pages: 1473-1483, ISSN: 0140-6736

JOURNAL ARTICLE

Cohen T, Colijn C, Finklea B, Murray Met al., 2007, Exogenous re-infection and the dynamics of tuberculosis epidemics: local effects in a network model of transmission, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 4, Pages: 523-531, ISSN: 1742-5689

JOURNAL ARTICLE

Colijn C, Cohen T, Murray M, 2007, MATHEMATICAL MODELS OF TUBERCULOSIS: ACCOMPLISHMENTS AND FUTURE CHALLENGES, International Symposium on Mathematical and Computational Biology (BIOMAT 2006), Publisher: WORLD SCIENTIFIC PUBL CO PTE LTD, Pages: 123-+

CONFERENCE PAPER

Colijn C, Cohen T, Murray M, 2007, Emergent heterogeneity in declining tuberculosis epidemics, JOURNAL OF THEORETICAL BIOLOGY, Vol: 247, Pages: 765-774, ISSN: 0022-5193

JOURNAL ARTICLE

Colijn C, Foley C, Mackey MC, 2007, G-CSF treatment of canine cyclical neutropenia: A comprehensive mathematical model, EXPERIMENTAL HEMATOLOGY, Vol: 35, Pages: 898-907, ISSN: 0301-472X

JOURNAL ARTICLE

Colijn C, Mackey MC, 2007, Bifurcation and bistability in a model of hematopoietic regulation, SIAM JOURNAL ON APPLIED DYNAMICAL SYSTEMS, Vol: 6, Pages: 378-394, ISSN: 1536-0040

JOURNAL ARTICLE

Colijn C, Dale DC, Foley C, Mackey MCet al., 2006, Observations on the Pathophysiology and Mechanisms for Cyclic Neutropenia, MATHEMATICAL MODELLING OF NATURAL PHENOMENA, Vol: 1, Pages: 45-68, ISSN: 0973-5348

JOURNAL ARTICLE

Colijn C, Fowler AC, Mackey MC, 2006, High frequency spikes in long period blood cell oscillations, JOURNAL OF MATHEMATICAL BIOLOGY, Vol: 53, Pages: 499-519, ISSN: 0303-6812

JOURNAL ARTICLE

Colijn C, Mackey MC, 2005, A mathematical model of hematopolesis: II. Cyclical neutropenia, JOURNAL OF THEORETICAL BIOLOGY, Vol: 237, Pages: 133-146, ISSN: 0022-5193

JOURNAL ARTICLE

Colijn C, Mackey MC, 2005, A mathematical model of hematopoiesis - I. Periodic chronic myelogenous leukemia, JOURNAL OF THEORETICAL BIOLOGY, Vol: 237, Pages: 117-132, ISSN: 0022-5193

JOURNAL ARTICLE

Colijn C, Vrscay ER, 2004, Quantum relaxation in hydrogen eigenstates and two-state transitions, PHYSICS LETTERS A, Vol: 327, Pages: 113-122, ISSN: 0375-9601

JOURNAL ARTICLE

Colijn C, Vrscay ER, 2003, Spin-dependent Bohm trajectories for hydrogen eigenstates (vol 300, pg 334, 2002), PHYSICS LETTERS A, Vol: 316, Pages: 424-424, ISSN: 0375-9601

JOURNAL ARTICLE

Colijn C, Vrscay ER, 2003, Spin-dependent Bohm trajectories for Pauli and Dirac eigenstates of hydrogen, FOUNDATIONS OF PHYSICS LETTERS, Vol: 16, Pages: 303-323, ISSN: 0894-9875

JOURNAL ARTICLE

Colijn C, Vrscay ER, 2003, Spin-dependent Bohm trajectories associated with an electronic transition in hydrogen, Journal of Physics A: Mathematical and General, Vol: 36, Pages: 4689-4702, ISSN: 0305-4470

JOURNAL ARTICLE

Colijn C, Vrscay ER, 2002, Spin-dependent Bohm trajectories for hydrogen eigenstates, PHYSICS LETTERS A, Vol: 300, Pages: 334-340, ISSN: 0375-9601

JOURNAL ARTICLE

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