Imperial College London

ProfessorCarloDi Mario

Faculty of MedicineNational Heart & Lung Institute

Professor in Cardiology
 
 
 
//

Contact

 

+44 (0)20 7351 8615c.dimario

 
 
//

Location

 

Sydney StreetRoyal Brompton Campus

//

Summary

 

Publications

Publication Type
Year
to

325 results found

Gutierrez-Chico JL, Raeber L, Regar E, Okamura T, di Mario C, van Es G-A, Windecker S, Serruys PWet al., 2013, Tissue coverage and neointimal hyperplasia in overlap versus nonoverlap segments of drug-eluting stents 9 to 13 months after implantation: In vivo assessment with optical coherence tomography, AMERICAN HEART JOURNAL, Vol: 166, Pages: 83-+, ISSN: 0002-8703

Journal article

Di Mario C, Secco G, 2013, Radial Primary Angioplasty The Gold Standard Treatment for STEMI Patients, JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 6, Pages: 707-708, ISSN: 1936-8798

Journal article

Ghione M, Agudo P, Kilickesmez K, Estevez-Loureiro R, Zivelonghi C, Lindsay A, Foin N, Secco GG, Di Mario Cet al., 2013, Tools and Techniques - Clinical: Catheter compatibility in CTO recanalisation, EUROINTERVENTION, Vol: 9, Pages: 290-291, ISSN: 1774-024X

Journal article

Foin N, Di Mario C, Francis DP, Davies JEet al., 2013, Stent flexibility versus concertina effect: Mechanism of an unpleasant trade-off in stent design and its implications for stent selection in the cath-lab, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 164, Pages: 259-261, ISSN: 0167-5273

Journal article

Di Mario C, Eltchaninoff H, Moat N, Goicolea J, Ussia GP, Kala P, Wenaweser P, Zembala M, Nickenig G, Barrero EA, Snow T, Iung B, Zamorano P, Schuler G, Corti R, Alfieri O, Prendergast B, Ludman P, Windecker S, Sabate M, Gilard M, Witowski A, Danenberg H, Schroeder E, Romeo F, Macaya C, Derumeaux G, Maggioni A, Tavazzi Let al., 2013, The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients, EUROINTERVENTION, Vol: 8, Pages: 1362-1371, ISSN: 1774-024X

Journal article

Di Mario C, Hildick-Smith D, Gershlick A, Ghione M, Agudo F, Alahmar A, Galassi A, Werner GSet al., 2013, Highlights from The Experts "Live", 4th annual congress of the Euro CTO Club, London 2012, EUROINTERVENTION, Vol: 8, Pages: 1359-1361, ISSN: 1774-024X

Journal article

Syrseloudis D, Secco GG, Barrero EA, Lindsay AC, Ghione M, Kilickesmez K, Foin N, Martos R, Di Mario Cet al., 2013, Increase in J-CTO lesion complexity score explains the disparity between recanalisation success and evolution of chronic total occlusion strategies: insights from a single-centre 10-year experience, HEART, Vol: 99, Pages: 474-479, ISSN: 1355-6037

Journal article

Costopoulos C, Gorog DA, Di Mario C, Kukreja Net al., 2013, Use of thrombectomy devices in primary percutaneous coronary intervention: A systematic review and meta-analysis, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 163, Pages: 229-241, ISSN: 0167-5273

Journal article

Chan PH, Alegria-Barrero E, Di Mario C, 2013, Difficulties with horizontal aortic root in transcatheter aortic valve implantation, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 81, Pages: 630-635, ISSN: 1522-1946

Journal article

Ghione M, Kilickesmez K, Di Mario C, 2013, Sealing old plaques, seeding new plaques, EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol: 14, Pages: 203-204, ISSN: 2047-2404

Journal article

Patel H, di Mario C, 2013, Microwaving metal! Can you get away with it? Renal denervation after stenting, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 81, Pages: 346-347, ISSN: 1522-1946

Journal article

Viceconte N, Tyczynski P, Ferrante G, Foin N, Chan PH, Barrero EA, Di Mario Cet al., 2013, Immediate results of bifurcational stenting assessed with optical coherence tomography, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 81, Pages: 519-528, ISSN: 1522-1946

Journal article

Chan PH, She HL, Alegria-Barrero E, Di Mario C, Moat N, Franzen Oet al., 2013, Effects of Dynamic Annular Shape Changes on Mitraclip Therapy and Combining Mitral Cerclage Annuloplasty - Reply, CIRCULATION JOURNAL, Vol: 77, Pages: 551-551, ISSN: 1346-9843

Journal article

Foin N, Mari JM, Davies JE, Di Mario C, Girard MJAet al., 2013, Imaging of coronary artery plaques using contrast-enhanced optical coherence tomography, EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol: 14, Pages: 85-85, ISSN: 2047-2404

Journal article

Foin N, Alegria-Barrero E, Torii R, Chan PH, Viceconte N, Davies JE, Di Mario Cet al., 2013, Crush, Culotte, T and Protrusion: Which 2-Stent Technique for Treatment of True Bifurcation Lesions? - Insights From In Vitro Experiments and Micro-Computed Tomography, CIRCULATION JOURNAL, Vol: 77, Pages: 73-80, ISSN: 1346-9843

Journal article

Moat N, Duncan A, Davies S, Di Mario C, Barker S, Snow TM, Trimlett RHJet al., 2013, How would I treat? THE INVITED EXPERTS' OPINION, EUROINTERVENTION, Vol: 8, Pages: 1105-1105, ISSN: 1774-024X

Journal article

Petraco R, Park JJ, Sen S, Nijjer SS, Malik IS, Echavarría-Pinto M, Asrress KN, Nam C, Macías E, Foale RA, Sethi A, Mikhail GW, Kaprielian R, Baker CS, Lefroy D, Bellamy M, Al-Bustami M, Khan MA, Gonzalo N, Hughes AD, Francis DP, Mayet J, Di Mario C, Redwood S, Escaned J, Koo B, Davies JEet al., 2013, Hybrid iFR-FFR decision-making strategy: implications for enhancing universal adoption of physiology-guided coronary revascularisation, EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Vol: 8, Pages: 1157-1165, ISSN: 1969-6213

AIMS: Adoption of fractional flow reserve (FFR) remains low (6-8%), partly because of the time, cost and potential inconvenience associated with vasodilator administration. The instantaneous wave-Free Ratio (iFR) is a pressure-only index of stenosis severity calculated without vasodilator drugs. Before outcome trials test iFR as a sole guide to revascularisation, we evaluate the merits of a hybrid iFR-FFR decision-making strategy for universal physiological assessment. METHODS AND RESULTS: Coronary pressure traces from 577 stenoses were analysed. iFR was calculated as the ratio between Pd and Pa in the resting diastolic wave-free window. A hybrid iFR-FFR strategy was evaluated, by allowing iFR to defer some stenoses (where negative predictive value is high) and treat others (where positive predictive value is high), with adenosine being given only to patients with iFR in between those values. For the most recent fixed FFR cut-off (0.8), an iFR of <0.86 could be used to confirm treatment (PPV of 92%), whilst an iFR value of >0.93 could be used to defer revascularisation (NPV of 91%). Limiting vasodilator drugs to cases with iFR values between 0.86 to 0.93 would obviate the need for vasodilator drugs in 57% of patients, whilst maintaining 95% agreement with an FFR-only strategy. If the 0.75-0.8 FFR grey zone is accounted for, vasodilator drug requirement would decrease by 76%. CONCLUSION: A hybrid iFR-FFR decision-making strategy for revascularisation could increase adoption of physiology-guided PCI, by more than halving the need for vasodilator administration, whilst maintaining high classification agreement with an FFR-only strategy.

Journal article

Foin N, Alegria E, Sen S, Petraco R, Nijjer S, Di Mario C, Francis DP, Davies JEet al., 2013, Importance of knowing stent design threshold diameters and post-dilatation capacities to optimise stent selection and prevent stent overexpansion/incomplete apposition during PCI, International journal of cardiology, Vol: 166, Pages: 755-758, ISSN: 1874-1754

Journal article

Foin N, Mari JM, Nijjer S, Sen S, Petraco R, Ghione M, Di Mario C, Davies JE, Girard MJAet al., 2013, Intracoronary imaging using attenuation-compensated optical coherence tomography allows better visualisation of coronary artery diseases, Cardiovascular revascularization medicine: including molecular interventions, ISSN: 1878-0938

PURPOSE: To allow an accurate diagnosis of coronary artery diseases by enhancing optical coherence tomography (OCT) images of atheromatous plaques using a novel automated attenuation compensation technique. BACKGROUND: One of the major drawbacks of coronary OCT imaging is the rapid attenuation of the OCT signal, limiting penetration in tissue to only few millimetres. Visualisation of deeper anatomy is however critical for accurate assessment of plaque burden in-vivo. METHODS: A compensation algorithm, previously developed to correct for light attenuation in soft tissues and to enhance contrast in ophthalmic OCT images, was applied to intracoronary plaque imaging using spectral-domain OCT. RESULTS: Application of the compensation algorithm significantly increased tissue contrast in the vessel wall and atherosclerotic plaque boundaries. Contrast enhancement allows a better differentiation of plaque morphology, which is particularly important for the identification of lipid rich fibro atheromatous plaques and to guide decision on treatment strategy. CONCLUSION: The analysis of arterial vessel structure clinically captured with OCT is improved when used in conjunction with automated attenuation compensation. This approach may improve the OCT-based interpretation of coronary plaque morphology in clinical practice.

Journal article

Sen S, Asrress KN, Nijjer S, Petraco R, Malik IS, Foale RA, Mikhail GW, Foin N, Broyd C, Hadjiloizou N, Sethi A, Al-Bustami M, Hackett D, Khan MA, Khawaja MZ, Baker CS, Bellamy M, Parker KH, Hughes AD, Francis DP, Mayet J, Di Mario C, Escaned J, Redwood S, Davies JEet al., 2013, Diagnostic Classification of the Instantaneous Wave-Free Ratio Is Equivalent to Fractional Flow Reserve and Is Not Improved With Adenosine Administration, Journal of the American College of Cardiology, Vol: 61, Pages: 1409-1420, ISSN: 0735-1097

Journal article

Foin N, Sen S, Allegria E, Petraco R, Nijjer S, Francis DP, Di Mario C, Davies JEet al., 2013, Maximal expansion capacity with current DES platforms: a critical factor for stent selection in the treatment of left main bifurcations?, EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Vol: 8, Pages: 1315-1325, ISSN: 1969-6213

AIMS: Left main stenting is increasingly performed and often involves deployment of a single stent across vessels with marked disparity in diameters. Knowing stent expansion capacity is critical to ensure adequate strut apposition after post-dilatation of the stent has been performed. Coronary stents are usually manufactured in only two or three different model designs with each design having a different maximal expansion capacity. Information about the different workhorse designs and their maximal achievable diameter is not commonly provided by manufacturers but, in the absence of this critically important information, stents implanted in segments with major changes in vessel diameter have the potential to become grossly overstretched and to remain incompletely apposed. METHODS AND RESULTS: We examined the differences in workhorse designs of six commercially available drug-eluting stents (DES): the PROMUS Element, Taxus Liberté, XIENCE Prime, Resolute Integrity, BioMatrix Flex and Cypher Select stents. Using micro-computed tomography, we tested oversizing capabilities above nominal pressures for the different workhorse designs of the six DES using 4.0, 5.0 and 6.0 mm post-dilatation balloons inflated to 14 atmospheres. MLD could be increased significantly in all stents, only restricted by workhorse design limitations. Minimal inner lumen diameter (MLD) achieved after two successive 6.0 mm post-dilatations of the largest design (4.0 mm stent) was 5.7 mm for the Element, 5.6 mm for the XIENCE Prime, 6.0 mm for the Taxus, 5.4 mm for the Resolute Integrity, 5.9 mm for the BioMatrix and 5.8 mm for the Cypher stent. Significant deformations were observed during stent oversizing with large changes in terms of cell opening and crowns expansion. These are affected by design structure and reveal important differences among all stents tested. Such extensive deformations may alter the functional ability of an individual stent to scaffold a lesion and prevent restenosis.

Journal article

Alegria-Barrero E, Chan PH, Di Mario C, 2012, New strategy for a stumpless aorto-ostial chronic total occlusion, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 161, Pages: E21-E22, ISSN: 0167-5273

Journal article

Borgia F, Viceconte N, Ali O, Stuart-Buttle C, Saraswathyamma A, Parisi R, Mirabella F, Dimopoulos K, Di Mario Cet al., 2012, Improved cardiac survival, freedom from mace and angina-related quality of life after successful percutaneous recanalization of coronary artery chronic total occlusions, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 161, Pages: 31-38, ISSN: 0167-5273

Journal article

Sen S, Petraco R, Nijjer S, Foin N, Broyd C, Foale R, Malik I, Mikhail G, Francis D, Hughes A, Mayet J, Di Mario C, Escaned J, Davies Jet al., 2012, The Diastolic Wave-Free Period Is The Most Suitable Period In The Cardiac Cycle For The Assessment Of A Coronary Stenosis: Implications For The Accurate Calculation Of The Instantaneous Wave-Free Ratio (iFR), Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B68-B68, ISSN: 0735-1097

Conference paper

Duncan A, Snow T, Di Mario C, Davies S, Moat Net al., 2012, TransAortic Valve Implantation (TAVI) Normalises Subendocardial Function in Patients with Severe Aortic Stenosis, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B254-B254, ISSN: 0735-1097

Conference paper

Serruys P, Buszman P, Linke A, Ischinger T, Antoni D, Klauss V, Sohn H-Y, Eberli F, Corti R, Wijns W, Morice M-C, Di Mario C, Juni P, Windecker Set al., 2012, LEADERS: 5-Year Follow-Up from a Prospective, Randomized Trial of Biolimus A9-Eluting Stents with a Biodegradable Polymer vs. Sirolimus-Eluting Stents with a Durable Polymer-Final report of the LEADERS study, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B13-B14, ISSN: 0735-1097

Conference paper

Gutierrez-Chico JL, Wykrzykowska J, Koch K, Koolen J, Di Mario C, Windecker S, Van Es GA, Juni P, Regar E, Serruys Pet al., 2012, Vascular tissue reaction to acute malapposition in human coronary arteries: sequential assessment with optical coherence tomography, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B82-B82, ISSN: 0735-1097

Conference paper

Duncan A, Snow T, Davies S, Di Mario C, Moat Net al., 2012, Flow Characteristics of the CoreValve and Potential Underestimation of Aortic Valve Cross-Sectional Area Following Transcatheter Valve Implantation, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B250-B250, ISSN: 0735-1097

Conference paper

Alegria E, Chan PH, Di Mario C, Snow T, Tavazzi G, Duncan A, Price S, Moat N, Franzen Oet al., 2012, Concept of the Central Clip: When to Use 1 or 2 MitraClips, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B227-B227, ISSN: 0735-1097

Conference paper

Ali O, Schultz C, Jabbour A, Rubens M, Amrani M, Di Mario C, Moat N, De Jaegere P, Dalby Met al., 2012, Catheter Laboratory Predictors Of Post Procedure Paraprosthetic Aortic Regurgitation Following Self-expanding Medtronic CoreValve Implantation: A Multicentre Registry Analysis, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B263-B263, ISSN: 0735-1097

Conference paper

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00398092&limit=30&person=true&page=2&respub-action=search.html