Summary
Channa Jayasena is an internationally recognized specialist in the field of reproductive endocrinology. He currently leads a research team at Imperial College London, and works as Consultant in Reproductive Endocrinology and Head of Andrology at St. Mary's & Hammersmith Hospitals, London. Dr. Jayasena qualified in medicine at Cambridge University, after which he undertook specialist training in Diabetes & Endocrinology in London.
Having been awarded a Wellcome Trust Clinical Research Training Fellowship and NIHR Clinical Lectureship, he conducted first-to-human studies at Imperial College investigating the clinical effects of novel hypothalamic neuropeptides such as kisspeptin on the human reproductive axis of men and women. Dr. Jayasena has also been awarded a prestigious NIHR Post-Doctoral Fellowship investigating the metabolic regulation of male infertility.
Dr. Jayasena co-chaired the 2021 Society for Endocrinology Guidelines for Testosterone Treatment in men Click for article
Dr. Jayasena leads the NIHR Health Technology Assessment Testosterone Efficacy & Safety (TestES) Consortium of researchers in 17 countries. TestES has provided the most comprehensive study to date on risks of cardiovascular events during testosterone treatment in men with low testosterone. Click for article
He has also conducted work revealing that partners of women with recurrent miscarriage have a high risk of sperm DNA damage and reactive oxidative stress Click for news feed
Dr. Jayasena's team is one of the few international centres with expertise in fertility treatment for men with azoospermia. They has developed cutting edge techniques such as seminal reactive oxygen species (ROS) measurement, microsurgical testicular sperm extraction (mTESE) and testicular mapping. Their work have advanced our understanding of the role of hormone stimulation during mTESE surgical sperm retrieval for men with azoospermia. Click for article
For details of clinical services available, click this link.
Publications
Journals
Hernández R, de Silva NL, Hudson J, et al., 2024, Cost-effectiveness of testosterone treatment utilising individual patient data from randomised controlled trials in men with low testosterone levels., Andrology, Vol:12, Pages:477-486
Mowla S, Farahani L, Tharakan T, et al., 2024, Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility, Elife, ISSN:2050-084X
Sharma A, Papanikolaou N, Abou Sherif S, et al., 2024, Improvements in sperm motility following low or high intensity dietary interventions in men with obesity, Journal of Clinical Endocrinology and Metabolism, Vol:109, ISSN:0021-972X, Pages:449-460
Li M, Chen L, Yan J, et al., 2024, Super‐resolution ultrasound localization microscopy for the non‐invasive imaging of human testicular microcirculation and its differential diagnosis role in male infertility, View, ISSN:2688-268X
Davies R, Minhas S, Jayasena CN, 2023, Next-Generation Sequencing to Elucidate the Semen Microbiome in Male Reproductive Disorders., Medicina (kaunas), Vol:60