Dr Cecilia Johansson is a Senior Lecturer in the Section of Respiratory Infections, at the National Heart and Lung Institute, Imperial College London.
Dr Johansson did her undergraduate studies at Umeå University and Lund University, Sweden. She then did her PhD in the Section for Immunology at Lund University under the supervision of Professor Mary Jo Wick working on Salmonella infection and dendritic cells. She subsequently trained as a postdoctoral fellow with Brian Kelsall at the National Institutes of Health, Bethesda, USA, studying the role of type I interferons (IFNs) during intestinal virus infection.
In 2008, Cecilia set up an independent research group at Imperial College supported initially by a Career Development Award from the Medical Research Council. Her lab focuses on the generation and regulation of immunity via cellular crosstalk in the lung during viral infections. In particular, the lab studies the impact of type I interferons on lung inflammation and how these cytokines influence the induction of both innate and adaptive immune responses. In addition, her lab investigates how respiratory viral infections influence primary and metastatic lung cancer.
Cecilia is a member of the Medical Research Club, Faculty of 1000 and the Asthma UK Centre for Asthma and Allergy. She is also a member of the Society for Mucosal Immunology Extramural Programs Committee and their membership committee. Cecilia also organises the Imperial CREST Academy through which Imperial College provides mentors for extracurricular science projects for 16-18 year old students. She is an associate editor for Mucosal Immunology and Frontiers in Immunology (Mucosal Immunology Section).
Makris S, Paulsen M, Johansson C, 2017, Type I interferons as regulators of lung inflammation, Frontiers in Immunology, Vol:8, ISSN:1664-3224
et al., 2017, Protective and Harmful Immunity to RSV Infection, Annual Review of Immunology, Vol:35, ISSN:0732-0582, Pages:501-532
Johansson C, 2016, Respiratory syncytial virus infection: an innate perspective., F1000research, Vol:5, ISSN:2046-1402
et al., 2016, Alveolar Macrophages Can Control Respiratory Syncytial Virus Infection in the Absence of Type I Interferons, Journal of Innate Immunity, Vol:8, ISSN:1662-8128
et al., 2015, T cell responses are elicited against Respiratory Syncytial Virus in the absence of signalling through TLRs, RLRs and IL-1R/IL-18R, Scientific Reports, Vol:5, ISSN:2045-2322
et al., 2015, Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes, Journal of Experimental Medicine, Vol:212, ISSN:0022-1007, Pages:699-714
et al., 2014, DNGR-1 is dispensable for CD8(+) T-cell priming during respiratory syncytial virus infection, European Journal of Immunology, Vol:44, ISSN:1521-4141, Pages:2340-2348
et al., 2014, Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection, Journal of Virology, Vol:88, ISSN:0022-538X, Pages:6128-6136
et al., 2013, Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells, Proceedings of the National Academy of Sciences of the United States of America, Vol:110, ISSN:0027-8424, Pages:2987-2992
et al., 2012, Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection, Mucosal Immunology, Vol:5, ISSN:1933-0219, Pages:161-172
et al., 2012, IL-10 Regulates Viral Lung Immunopathology during Acute Respiratory Syncytial Virus Infection in Mice, PLOS One, Vol:7, ISSN:1932-6203
et al., 2007, Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus, Journal of Experimental Medicine, Vol:204, ISSN:0022-1007, Pages:1349-1358