Imperial College London
Portrait Picture

Mr Christos Kontovounisios

Faculty of Medicine, Department of Surgery & Cancer

Visiting Reader
 
 
 
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Contact

 

+44 (0)20 3315 8529c.kontovounisios

 
 
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Location

 

Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Fadel:2021:10.1016/j.burns.2021.04.018,
author = {Fadel, MG and Iskandarani, M and Cuddihy, J and Jones, I and Collins, D and Kontovounisios, C},
doi = {10.1016/j.burns.2021.04.018},
journal = {Burns},
pages = {1241--1251},
title = {Colonic perforation following major burns: experience from a burns center and a systematic review},
url = {http://dx.doi.org/10.1016/j.burns.2021.04.018},
volume = {47},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundMajor burns complicated by stress ulceration and perforation of the stomach or duodenum is a recognized clinical phenomenon. Colonic perforation in burns patients is not common, and the overall incidence, diagnosis, intervention undertaken and mortality is incompletely described in the literature.MethodWe performed a systematic review of the literature on severe burns resulting in colonic perforation during the initial admission period. Relevant studies from January 1975 to June 2020 were retrieved from MEDLINE and EMBASE databases. Patient demographics, co-morbidities, total body surface area (TBSA) and anatomical region of burn, site of colonic perforation and management, nutrition, sepsis and microbiology, length of stay and overall outcome were extracted. We present a case series of five burns patients who had colonic perforations in our Specialist Burns Center.ResultsWe identified 54 studies, of which nine (two case series and seven case reports) met the inclusion criteria. Colonic perforation following burns was most common in middle-aged male patients with a proportion of patients having a history of mental health issues. In most cases, the TBSA associated with a colonic perforation was ≥30% (11/16 patients, 69%). Perforations mainly affected the right side of the colon (12/16 patients, 75%), usually occurring after the second week of admission (13/16 patients, 81%). Right-sided colonic perforations were associated with an increased mortality rate compared to left-sided perforations (42% vs 25%).ConclusionsThe current literature is mainly limited to case series and case reports and confirms that colonic perforations in burns patients are rare. Colonic perforations are related to the systemic effect of burn injuries including sepsis and gastrointestinal stasis. We have identified patients who are at higher risk of developing colonic perforations and have described the common findings in these patients. Through greater awareness early diagnosis and
AU  - Fadel,MG
AU  - Iskandarani,M
AU  - Cuddihy,J
AU  - Jones,I
AU  - Collins,D
AU  - Kontovounisios,C
DO  - 10.1016/j.burns.2021.04.018
EP  - 1251
PY  - 2021///
SN  - 0305-4179
SP  - 1241
TI  - Colonic perforation following major burns: experience from a burns center and a systematic review
T2  - Burns
UR  - http://dx.doi.org/10.1016/j.burns.2021.04.018
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000691216600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.sciencedirect.com/science/article/pii/S0305417921001078
VL  - 47
ER  -
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