Imperial College London
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DrChiu FanLee

Faculty of Engineering, Department of Bioengineering

Reader in Theoretical Biophysics
 
 
 
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Contact

 

+44 (0)20 7594 6493c.lee Website

 
 
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Location

 

3.17Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Folkmann:2021:10.1126/science.abg7071,
author = {Folkmann, A and Putnam, A and Lee, CF and Seydoux, G},
doi = {10.1126/science.abg7071},
journal = {Science},
pages = {1218--1224},
title = {Regulation of biomolecular condensates by interfacial protein clusters},
url = {http://dx.doi.org/10.1126/science.abg7071},
volume = {373},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Pickering emulsions, droplet suspensions stabilized by solid particles, were discovered more than 100 years ago and are well studied in foods, oils, cosmetics, and pharmaceuticals. The particles adsorb to the droplet interface and prevent the emulsion from coarsening. Folkmann et al. report that P granules, biomolecular condensates in Caenorhabditis elegans, are an example of an intracellular Pickering emulsion (see the Perspective by Snead and Gladfelter). Biomolecular condensates are cellular compartments that form without traditional lipid membranes. This work raises the possibility that Pickering agents fulfill the role of membranes in biomolecular condensates. —DJ
AU  - Folkmann,A
AU  - Putnam,A
AU  - Lee,CF
AU  - Seydoux,G
DO  - 10.1126/science.abg7071
EP  - 1224
PY  - 2021///
SN  - 0036-8075
SP  - 1218
TI  - Regulation of biomolecular condensates by interfacial protein clusters
T2  - Science
UR  - http://dx.doi.org/10.1126/science.abg7071
UR  - https://www.science.org/doi/10.1126/science.abg7071
UR  - http://hdl.handle.net/10044/1/90700
VL  - 373
ER  -
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