Imperial College London
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DrChiu FanLee

Faculty of Engineering, Department of Bioengineering

Reader in Theoretical Biophysics
 
 
 
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Contact

 

+44 (0)20 7594 6493c.lee Website

 
 
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Location

 

3.17Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Nesbitt:2017:10.1103/PhysRevE.96.062615,
author = {Nesbitt, D and Pruessner, G and Lee, C},
doi = {10.1103/PhysRevE.96.062615},
journal = {Physical Review E},
title = {Edge instability in incompressible planar active fluids},
url = {http://dx.doi.org/10.1103/PhysRevE.96.062615},
volume = {96},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Interfacial instability is highly relevant to many important biological processes. A key example arises in wound healing experiments, which observe that an epithelial layer with an initially straight edge does not heal uniformly. We consider the phenomenon in the context of active fluids. Improving upon the approximation used by Zimmermann, Basan, and Levine [Eur. Phys. J.: Spec. Top. 223, 1259 (2014)], we perform a linear stability analysis on a two-dimensional incompressible hydrodynamic model of an active fluid with an open interface. We categorize the stability of the model and find that for experimentally relevant parameters, fingering instability is always absent in this minimal model. Our results point to the crucial role of density variation in the fingering instability in tissue regeneration.
AU  - Nesbitt,D
AU  - Pruessner,G
AU  - Lee,C
DO  - 10.1103/PhysRevE.96.062615
PY  - 2017///
SN  - 1539-3755
TI  - Edge instability in incompressible planar active fluids
T2  - Physical Review E
UR  - http://dx.doi.org/10.1103/PhysRevE.96.062615
UR  - http://hdl.handle.net/10044/1/74889
VL  - 96
ER  -
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