Imperial College London
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Professor Christoph Lees, MD FRCOG

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor of Obstetrics
 
 
 
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Contact

 

+44 (0)20 7594 5770c.lees

 
 
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Assistant

 

Ms Hazel Blackman +44 (0)20 7594 2104

 
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Location

 

Queen Charlottes and Chelsea HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Clarke:2020:10.1098/rsos.201342,
author = {Clarke, A and Biffi, B and Sivera, R and Dall'Asta, A and Fessey, L and Wong, T-L and Paramasivam, G and Dunaway, D and Schievano, S and Lees, C},
doi = {10.1098/rsos.201342},
journal = {Royal Society Open Science},
title = {Developing and testing an algorithm for automatic segmentation of the fetal face from 3D ultrasound images},
url = {http://dx.doi.org/10.1098/rsos.201342},
volume = {7},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Fetal craniofacial abnormalities are challenging to detect and diagnose on prenatal ultrasound (US). Image segmentation and computer analysis of three-dimensional US volumes of the fetal face may provide an objective measure to quantify fetal facial features and identify abnormalities. We have developed and tested an atlas-based partially automated facial segmentation algorithm; however, the volumes require additional manual segmentation (MS), which is time and labour intensive and may preclude this method from clinical adoption. These manually refined segmentations can then be used as a reference (atlas) by the partially automated segmentation algorithm to improve algorithmic performance with the aim of eliminating the need for manual refinement and developing a fully automated system. This study assesses the inter- and intra-operator variability of MS and tests an optimized version of our automatic segmentation (AS) algorithm. The manual refinements of 15 fetal faces performed by three operators and repeated by one operator were assessed by Dice score, average symmetrical surface distance and volume difference. The performance of the partially automatic algorithm with difference size atlases was evaluated by Dice score and computational time. Assessment of the manual refinements showed low inter- and intra-operator variability demonstrating its suitability for optimizing the AS algorithm. The algorithm showed improved performance following an increase in the atlas size in turn reducing the need for manual refinement.
AU  - Clarke,A
AU  - Biffi,B
AU  - Sivera,R
AU  - Dall'Asta,A
AU  - Fessey,L
AU  - Wong,T-L
AU  - Paramasivam,G
AU  - Dunaway,D
AU  - Schievano,S
AU  - Lees,C
DO  - 10.1098/rsos.201342
PY  - 2020///
SN  - 2054-5703
TI  - Developing and testing an algorithm for automatic segmentation of the fetal face from 3D ultrasound images
T2  - Royal Society Open Science
UR  - http://dx.doi.org/10.1098/rsos.201342
UR  - http://hdl.handle.net/10044/1/84690
VL  - 7
ER  -
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