Summary
For more information on the lab, including details of any open position, visit our group website here.
Research
Dr Lo Celso’s work focuses on the dynamic processes underlying healthy and malignant haematopoiesis, using an interdisciplinary approach that combines advanced intravital microscopy, computational image analysis, flow cytometry and mathematical modelling.
Recruitment
From time to time there may be open positions to join Dr Lo Celso’s research team. These will be posted on the group website (here: link to http://www3.imperial.ac.uk/locelsolab/group). If there are no open positions but you are interested in joining the group as a postdoc or PhD student, please get in touch directly via email.
Teaching
Dr Lo Celso teaches and co-organises with Dr Anita Hall the Stem Cells, Regeneration and Ageing (SCRA) course for the 3rd year of the Biochemistry and Biology degrees. She also teaches development of the immune system and haematopoietic stem cell biology in the Immunology courses of Biochemistry and Biology degrees and cell and stem cell biology in the Cell and Developmental Biology course of the Biology degree. These are 2nd year courses.
Dr Lo Celso runs a number of tutorials for first, second and third year courses as well as the SCRA practical. She is personal tutor for the Biochemistry degree, supervises third year literature projects and accommodates third year Biochemistry laboratory projects within her research group.
Dr Lo Celso provides lectures on stem cell biology and intravital microscopy for the MSc Applied Biosciences and Biotechnology and the MSc, PG Cert Genes, Drugs and Stem Cells - Novel Therapies. She is guest lecturer at Queen Mary University in the Regenerative Medicine Msc and was faculty at the Hydra Stem Cells summer school 2016
Publications
Journals
Tissot FS, Gonzalez-Anton S, Lo Celso C, 2024, Intravital Microscopy to Study the Effect of Matrix Metalloproteinase Inhibition on Acute Myeloid Leukemia Cell Migration in the Bone Marrow., Methods Mol Biol, Vol:2747, Pages:211-227
Grockowiak E, Korn C, Rak J, et al., 2023, Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms, Nature Cancer
Partridge B, Gonzalez Anton S, Khorshed R, et al., 2022, Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells, Plos One, Vol:17, ISSN:1932-6203, Pages:1-26
Pirillo C, Birch F, Tissot FS, et al., 2022, Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness, Blood Advances, Vol:6, ISSN:2473-9529, Pages:3126-3141
Zhou L, Kong G, Palmisano I, et al., 2022, Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline., Science, Vol:376, ISSN:0036-8075, Pages:1-15