Summary
Dr Charalambos Michaeloudes is an Honorary Research Fellow at the Airway Disease Section of the National Heart and Lung Institute. His research aims to understand the cellular and molecular mechanisms leading to the development of airway remodelling in asthma and chronic obstructive pulmonary disease (COPD), in order to identify novel therapeutic targets for these diseases.
Research interests:
- Molecular mechanisms regulating the adaptation of airways to oxidative stress
- Role of redox signalling in the development of airway remodelling
- Mitochondrial dysfunction and metabolic re-programming in asthma and COPD
- Molecular mechanisms of intracellular and intercellular mitochondrial movement
Dr Michaeloudes has received funding from the Imperial Centre for Translational and Experimental Medicine and the British Heart Foundation, and the European Respiratory Society. He has published articles in leading medical and scientific journals and has given numerous talks at national and international conferences.
He serves as a manuscript reviewer for medical and scientific journals, a grant reviewer for national and international funding bodies, and as an abstract reviewer for the European Respiratory Society International Congress. He has also been invited as a member of the European Respiratory Society College of Experts.
Dr Michaeloudes teaches on undergraduate and postgraduate programmes and is a PhD co-supervisor.
Publications
Journals
Koranteng J, Chung KF, Michaeloudes C, et al., 2024, The role of mitochondria in eosinophil function: implications for severe asthma pathogenesis., Front Cell Dev Biol, Vol:12, ISSN:2296-634X
Michaeloudes C, Christodoulides S, Christodoulou P, et al., 2023, Variability in the Clinical Effects of the Omega-3 Polyunsaturated Fatty Acids DHA and EPA in Cardiovascular Disease-Possible Causes and Future Considerations., Nutrients, Vol:15
Raby KL, Michaeloudes C, Tonkin J, et al., 2023, Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD, Frontiers in Immunology, Vol:14, ISSN:1664-3224, Pages:1-14
Conference
Koranteng JB, Lai S, Raby KL, et al., 2023, Role of Eosinophil Mitochondrial Function in Severe Eosinophilic Asthma, International Conference of the American-Thoracic-Society (ATS), AMER THORACIC SOC, ISSN:1073-449X