Imperial College London

ProfessorChristopherMillett

Faculty of MedicineSchool of Public Health

Professor of Public Health
 
 
 
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Contact

 

c.millett Website

 
 
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Location

 

Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Hone:2020:10.1371/journal.pmed.1003357,
author = {Hone, T and Saraceni, V and Coeli, CM and Trajman, A and Rasella, D and Millett, C and Durovni, B},
doi = {10.1371/journal.pmed.1003357},
journal = {PLoS Medicine},
pages = {1--20},
title = {Primary health care expansion and mortality in Brazil’s urban poor: a cohort analysis of 1.2 million adults},
url = {http://dx.doi.org/10.1371/journal.pmed.1003357},
volume = {17},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundExpanding delivery of primary health care to urban poor populations is a priority in many low-and middle-income countries. This remains a key challenge in Brazil despite expansion of the country’s internationally recognised Family Health Strategy (FHS) over the past two decades. This study evaluates the impact of an ambitious program to rapidly expand FHS coverage in the city of Rio de Janeiro, Brazil since 2008. Methods and FindingsA cohort of 1,241,351 million low-income adults (observed January 2010-December 2016; total person-years 6,498,607) with linked FHS utilisation and mortality records was analysed using flexible parametric survival models. Time-to-death from all-causes and selected causes were estimated for FHS users and non-users. Models employed inverse probability treatment weighting and regression adjustment (IPTW-RA).The cohort was 61% female (751,895) and had a mean age of 36 years (standard deviation 16.4). Only 18,721 individuals (1.5%) had higher education whilst 102,899 (8%) had no formal education. Two-thirds of individuals (827250; 67%) were in receipt of conditional cash transfers (Bolsa Família). A total of 34,091 deaths were analysed of which 8,765 (26%) were due to cardiovascular disease, 5,777 (17%) due to neoplasms, 5,683 (17%) due to external causes, 3,152 (9%) due to respiratory diseases, and 3,115 (9%) due to infectious and parasitic diseases. One third of the cohort (467,155; 37.6%) used FHS services. In IPTW-RA survival analysis, an average FHS user had a 44% lower hazard of all-cause mortality (HR: 0.56, 95%CI: 0.54 to 0.59, p<0.001) and a five-year risk reduction of 8.3 per 1000 (95%CI: 7.8 to 8.9, p<0.001) compared to a non-FHS user. There were greater reductions in the risk of death for FHS users who: were black (HR:0.50 (95%CI: 0.46 to 0.54, p<0.001)) or pardo (HR:0.57 (95%CI: 0.54 to 0.60, p<0.001) compared to white (HR:0.59 (95%CI: 0.56 to 0.63, p<0.001); had lower educational attainment
AU - Hone,T
AU - Saraceni,V
AU - Coeli,CM
AU - Trajman,A
AU - Rasella,D
AU - Millett,C
AU - Durovni,B
DO - 10.1371/journal.pmed.1003357
EP - 20
PY - 2020///
SN - 1549-1277
SP - 1
TI - Primary health care expansion and mortality in Brazil’s urban poor: a cohort analysis of 1.2 million adults
T2 - PLoS Medicine
UR - http://dx.doi.org/10.1371/journal.pmed.1003357
UR - https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003357
UR - http://hdl.handle.net/10044/1/83436
VL - 17
ER -