Summary
Charles Pusey is Emeritus Professor of Medicine in the Department of Immunology and Inflammation at Imperial College London, and Honorary Consultant Physician at Imperial College Healthcare NHS Trust. He is Director of the Imperial Centre of Excellence in Vasculitis Research.
Charles has now retired from clinical practice, but remains active in research and teaching. He is a clinician scientist with a particular interest in autoimmune kidney disease, including primary systemic vasculitis and anti-GBM disease. He previously led a large multidisciplinary vasculitis clinic, and has made a major contribution to many of the international clinical trials in this field. He also led, and still contributes to, a laboratory research program investigating mechanisms of autoimmunity and inflammation in glomerulonephritis.
Charles is a Fellow of the Academy of Medical Sciences, and NIHR Senior Investigator Emeritus. He serves as Scientific Advisor to Vasculitis UK, and Senior Advisor to the UK and Ireland Vasculitis Society
Selected Publications
Journal Articles
Reynolds J, Preston GA, Pressler BM, et al., 2015, Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity', Journal of Autoimmunity, Vol:59, ISSN:0896-8411, Pages:8-18
McAdoo SP, Reynolds J, Bhangal G, et al., 2014, Spleen tyrosine kinase inhibition attenuates autoantibody production and reverses experimental autoimmune GN, Journal of the American Society of Nephrology, Vol:25, ISSN:1046-6673, Pages:2291-2302
Little MA, Smyth L, Salama AD, et al., 2009, Experimental Autoimmune Vasculitis <i>An Animal Model of Anti-neutrophil Cytoplasmic Autoantibody-Associated Systemic Vasculitis</i>, American Journal of Pathology, Vol:174, ISSN:0002-9440, Pages:1212-1220