DrChristopherRowlands

Kong K, Rowlands CJ, Varma S, Perkins W, Leach IH, Koloydenko AA, Pitiot A, Williams HC, Notingher Iet al., 2014, Increasing the speed of tumour diagnosis during surgery with selective scanning Raman microscopy, JOURNAL OF MOLECULAR STRUCTURE, Vol: 1073, Pages: 58-65, ISSN: 0022-2860

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• Citations: 10

Yew E, Rowlands C, So PTC, 2014, Application of multiphoton microscopy in dermatological studies: A mini-review, JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, Vol: 7, ISSN: 1793-5458

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• Citations: 55

Marcu L, French PMW, Elson DS, 2014, Preface, ISBN: 9781439861677

Wide-field time-gated fluorescence lifetime imaging (FLIM) essentially entails illuminating a sample with an ultrashort pulse of excitation radiation and sampling the resulting time varying fluorescence “image” following excitation by acquiring a series of gated fluorescence intensity images recorded at different relative delays with respect to the excitation pulse. This is represented schematically in Figure 8.1. In the simplest case, a map of the mean fluorescence decay times across the field of view is obtained. If the sampling of the fluorescence decay profiles is appropriately detailed, then the entire fluorescence decay profile for each image pixel can be acquired, and the resulting data set can be fitted to complex temporal decay models. For example, a double exponential decay model is frequently used to analyze data from Förster resonant energy transfer (FRET) experiments. The acquisition of time-gated fluorescence intensity images requires a 2-D detector, normally a charge-coupled device (CCD) camera, and some kind of fast “shutter” able to sample fluorescence decay profiles on subnanosecond timescales. Such a “shutter” function cannot be provided by mechanical means or yet by electronic circuitry and is typically provided by optical image intensifiers whose gain can be modulated by varying the applied voltage.

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• Citations: 92

So PTC, Yew EYS, Rowlands C, 2013, High-Throughput Nonlinear Optical Microscopy, BIOPHYSICAL JOURNAL, Vol: 105, Pages: 2641-2654, ISSN: 0006-3495

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• Citations: 31

Kong K, Rowlands CJ, Varma S, Perkins W, Leach IH, Koloydenko AA, Williams HC, Notingher Iet al., 2013, Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 110, Pages: 15189-15194, ISSN: 0027-8424

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• Citations: 179

Rowlands CJ, Yew EYS, So PTC, 2013, Parallel super-resolution imaging, NATURE METHODS, Vol: 10, Pages: 709-710, ISSN: 1548-7091

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• Citations: 2

Rowlands CJ, So PTC, 2013, On the correction of errors in some multiple particle tracking experiments, APPLIED PHYSICS LETTERS, Vol: 102, ISSN: 0003-6951

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• Citations: 9

Rowlands CJ, Varma S, Perkins W, Leach I, Williams H, Notingher Iet al., 2012, Rapid acquisition of Raman spectral maps through minimal sampling: applications in tissue imaging, JOURNAL OF BIOPHOTONICS, Vol: 5, Pages: 220-229, ISSN: 1864-063X

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• Citations: 37

Rowlands CJ, Notingher I, 2012, Selective sampling in hyperspectral raman micro-spectroscopy: Obtaining maximum data with minimal sampling time

We present a new method for selectively sampling hyperspectral Raman maps in order to maximize the information that can be obtained for a given sample time. Example maps and comparisons with alternative methods are provided. © OSA 2012.

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Kong K, Rowlands CJ, Elsheikha H, Notingher Iet al., 2012, Label-free molecular analysis of live <i>Neospora caninum</i> tachyzoites in host cells by selective scanning Raman micro-spectroscopy, ANALYST, Vol: 137, Pages: 4119-4122, ISSN: 0003-2654

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• Citations: 17

Rowlands CJ, Elliott SR, 2011, Improved blind-source separation for spectra, JOURNAL OF RAMAN SPECTROSCOPY, Vol: 42, Pages: 1761-1768, ISSN: 0377-0486

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• Citations: 7

Rowlands C, Elliott S, 2011, Automated algorithm for baseline subtraction in spectra, JOURNAL OF RAMAN SPECTROSCOPY, Vol: 42, Pages: 363-369, ISSN: 0377-0486

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• Citations: 32

Rowlands CJ, Elliott SR, 2011, Denoising of spectra with no user input: a spline-smoothing algorithm, JOURNAL OF RAMAN SPECTROSCOPY, Vol: 42, Pages: 370-376, ISSN: 0377-0486

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• Citations: 13

Rowlands CJ, Su L, Elliott SR, 2010, Investigating the response of As₂S₃-based SERS substrates, OPTICAL MATERIALS, Vol: 32, Pages: 1413-1416, ISSN: 0925-3467

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• Citations: 2

Rowlands CJ, Su L, Elliott SR, 2010, Rapid Prototyping of Low-Loss IR Chalcogenide-Glass Waveguides by Controlled Remelting, CHEMPHYSCHEM, Vol: 11, Pages: 2393-2398, ISSN: 1439-4235

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• Citations: 5

Su L, Rowlands CJ, Elliott SR, 2009, Nanostructures fabricated in chalcogenide glass for use as surface-enhanced Raman scattering substrates, OPTICS LETTERS, Vol: 34, Pages: 1645-1647, ISSN: 0146-9592

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• Citations: 19

Su L, Rowlands CJ, Lee TH, Elliott SRet al., 2008, Fabrication of photonic waveguides in sulfide chalcogenide glasses by selective wet-etching, ELECTRONICS LETTERS, Vol: 44, Pages: 472-473, ISSN: 0013-5194

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• Citations: 4

Rowlands C, Winkle R, Wootton R, de Mello Aet al., 2007, Microfluidic reaction optmisation using intelligent feedback, Pages: 850-852

A system for the automated optimisation of chemical reactions within microfluidic devices using intelligent feedback is described. Various search algorithms are employed and their utility and performance compared.

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