Imperial College London
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Dr Charlotte-Eve Short

Faculty of Medicine, Department of Infectious Disease

Academic Clinical Lecturer
 
 
 
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Contact

 

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Location

 

VD4, Variety wingNorfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Short:2014:10.1177/0956462413492714,
author = {Short, C-ES and Shaw, SG and Fisher, MJ and Walker-Bone, K and Gilleece, YC},
doi = {10.1177/0956462413492714},
journal = {International Journal of STD and AIDS},
pages = {113--121},
title = {Prevalence of and risk factors for osteoporosis and fracture among a male HIV-infected population in the UK.},
url = {http://dx.doi.org/10.1177/0956462413492714},
volume = {25},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Rates of osteoporosis and fracture may be increased in HIV but there are few UK data. Our aim was to examine the prevalence of and risk factors for osteoporosis and fractures among a homogeneous cohort of well-characterized HIV-infected men. In total, 168 men were recruited, median age 45 years, 37 combination antiretroviral therapy (cART) naïve, 46 with <3 years cART exposure and 85 cART-exposed longer term (median >10 years). All participants provided information on bone health and underwent DEXA scanning. Osteopenia was found in 58% of subjects and osteoporosis in 12%; 14% reported fractures since HIV diagnosis. Number of fractures since HIV diagnosis was significantly increased among those with osteoporosis (OR 3.5, 95% CI 1.2-10.4, p = 0.018). Duration of infection greater than 13 years was significantly associated with osteoporosis. Duration of cART was associated in univariate but not multivariate analyses. Strategies to prevent osteoporosis and fractures in HIV will require attention to viral and lifestyle factors and not just cART.
AU  - Short,C-ES
AU  - Shaw,SG
AU  - Fisher,MJ
AU  - Walker-Bone,K
AU  - Gilleece,YC
DO  - 10.1177/0956462413492714
EP  - 121
PY  - 2014///
SN  - 0956-4624
SP  - 113
TI  - Prevalence of and risk factors for osteoporosis and fracture among a male HIV-infected population in the UK.
T2  - International Journal of STD and AIDS
UR  - http://dx.doi.org/10.1177/0956462413492714
UR  - https://www.ncbi.nlm.nih.gov/pubmed/23970632
UR  - https://journals.sagepub.com/doi/10.1177/0956462413492714
UR  - http://hdl.handle.net/10044/1/85187
VL  - 25
ER  -
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