Imperial College London
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Dr Charlotte-Eve Short

Faculty of Medicine, Department of Infectious Disease

Academic Clinical Lecturer
 
 
 
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Contact

 

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Location

 

VD4, Variety wingNorfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Harris:2021:infdis/jiaa610,
author = {Harris, BHL and Zuhair, M and Di, Giovannantonio M and Rosadas, C and Khan, M and Short, C-E and Thaventhiran, T and Quinlan, R and Taylor, A and Calvez, R and Taylor, GP and Tedder, RS and McClure, MO and Fertleman, M},
doi = {infdis/jiaa610},
journal = {Journal of Infectious Diseases},
pages = {192--196},
title = {Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a rehabilitation facility: evolution of the presence of nasopharyngeal SARS-CoV-2 and serological antibody responses.},
url = {http://dx.doi.org/10.1093/infdis/jiaa610},
volume = {223},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - At the start of the UK coronavirus disease 2019 epidemic, this rare point prevalence study revealed that one-third of patients (15 of 45) in a London inpatient rehabilitation unit were found to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but asymptomatic. We report on 8 patients in detail, including their clinical stability, the evolution of their nasopharyngeal viral reverse-transcription polymerase chain reaction (RT-PCR) burden, and their antibody levels over time, revealing the infection dynamics by RT-PCR and serology during the acute phase. Notably, a novel serological test for antibodies against the receptor binding domain of SARS-CoV-2 showed that 100% of our asymptomatic cohort remained seropositive 3-6 weeks after diagnosis.
AU  - Harris,BHL
AU  - Zuhair,M
AU  - Di,Giovannantonio M
AU  - Rosadas,C
AU  - Khan,M
AU  - Short,C-E
AU  - Thaventhiran,T
AU  - Quinlan,R
AU  - Taylor,A
AU  - Calvez,R
AU  - Taylor,GP
AU  - Tedder,RS
AU  - McClure,MO
AU  - Fertleman,M
DO  - infdis/jiaa610
EP  - 196
PY  - 2021///
SN  - 0022-1899
SP  - 192
TI  - Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a rehabilitation facility: evolution of the presence of nasopharyngeal SARS-CoV-2 and serological antibody responses.
T2  - Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1093/infdis/jiaa610
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33535238
UR  - http://hdl.handle.net/10044/1/85981
VL  - 223
ER  -
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