Charlotte is a Senior Teaching Fellow, specialising in Organic and Medicinal Chemistry. She is involved in a variety of teaching within the Department of Chemistry and is currently a course coordinator for the Chemistry with Medicinal Chemistry degree programme and a Year Tutor for 3rd Year Undergraduates. Within education, her interests are particularly related how assessment and feedback can be designed most effectively to support student learning and skills development.
Before becoming a Teaching Fellow in 2018, Charlotte had been a member of Imperial College since 2016 as a Postdoctoral Research Associate in the group of Professor Ed Tate, working on a Cancer Research UK funded medicinal chemistry project. She has been closely associated with the MRes in Drug Discovery and Development Programme, helping supervise students conducting a wide variety of medicinal chemistry research projects.
Charlotte graduated from the University of Oxford in 2011 with a first-class MChem, completing her final year project with Professor Andrew D. Hamilton on peptide mimetics. Having become fascinated by the challenges and possibilities in applying chemistry to solve biological problems, she moved to the University of Cambridge for her PhD and was a member of the PhD Training Programme in Chemical Biology and Medicinal Chemistry. She completed her PhD under the supervision of Professor Steven V. Ley and Dr James D. Brenton, developing chemical probes of bromodomain to study their therapeutic relevance in ovarian cancer.
Beyond chemistry, Charlotte is a keen musician and singer, and is a currently a member of The Bach Choir.
et al., 2019, Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus, Bioorganic & Medicinal Chemistry, Vol:27, ISSN:0968-0896, Pages:1-7
Lovell S, Sutherell CL, Tate EW, 2019, Chemical probes for proteins and networks, Pages:127-158
Sutherell CL, Ley SV, 2017, On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones, Synthesis-Stuttgart, Vol:49, ISSN:0039-7881, Pages:135-144
et al., 2016, Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex, Journal of Medicinal Chemistry, Vol:59, ISSN:0022-2623, Pages:5095-5101
et al., 2012, Aryl-linked imidazolidin-2-ones as non-peptidic beta-strand mimetics, Chemical Communications, Vol:48, ISSN:1359-7345, Pages:9834-9836