Carolin is a computational biologist at the Department of Infectious Disease Epidemiology at Imperial College London. Her main interests are stochastic simulation models of complex systems and clinical trial simulations. Currently, she is working with Roy Anderson on modelling the evolution of antimicrobial resistance and evaluating strategies to reduce the risk of resistance development to novel antimicrobials. Previous projects include clinical trial simulators for novel immunotherapies for influenza and Alzheimer’s disease and on identifying biomarkers for type II diabetes. She has also worked on vaccine development for pneumococcal diseases and molecular diagnostics for antimicrobial resistance.
Carolin holds a PhD in Biological Anthropology from the University of Cambridge. Her research interests include quantitative modelling of cultural evolution and the cognitive and social processes involved in innovation.
et al., 2018, Defining stopping criteria for ending randomized clinical trials that investigate the interruption of transmission of soil-transmitted helminths employing mass drug administration, Plos Neglected Tropical Diseases, Vol:12, ISSN:1935-2727
et al., 2017, A Systematic Review of Longitudinal Studies Which Measure Alzheimer's Disease Biomarkers, Journal of Alzheimers Disease, Vol:59, ISSN:1387-2877, Pages:1359-1379
et al., 2016, How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?, Plos One, Vol:11, ISSN:1932-6203
et al., 2016, Using Clinical Trial Simulators to Analyse the Sources of Variance in Clinical Trials of Novel Therapies for Acute Viral Infections., Plos One, Vol:11, ISSN:1932-6203
et al., 2018, MIGRATION AND LOCAL MOVEMENT CAN IMPEDE ELIMINATION EFFORTS OF SOIL-TRANSMITTED HELMINTHS (STH) BY MASS DRUG ADMINISTRATION (MDA), 67th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTHM), AMER SOC TROP MED & HYGIENE, Pages:239-239, ISSN:0002-9637