Imperial College London

DrCarolynWebb

Faculty of MedicineNational Heart & Lung Institute

Research Fellow
 
 
 
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Contact

 

+44 (0)20 7351 8860c.webb Website

 
 
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Location

 

3013Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

79 results found

Webb C, Collins P, 2003, Estrogen and adenosine triphosphate - Sensitive potassium channels, CIRCULATION, Vol: 107, Pages: E221-E221, ISSN: 0009-7322

Journal article

Sorensen MB, Collins P, Ong PJL, Webb CM, Hayward CS, Asbury EA, Gatehouse PD, Elkington AG, Yang GZ, Kubba A, Pennell DJet al., 2002, Long-term use of contraceptive depot medroxyprogesterone acetate in young women impairs arterial endothelial function assessed by cardiovascular magnetic resonance, CIRCULATION, Vol: 106, Pages: 1646-1651, ISSN: 0009-7322

Journal article

Ong PJL, Webb CM, Sorensen MB, Hayward CS, Collins Pet al., 2002, A comparison of brachial artery reactivity measured by external and intravascular ultrasound, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 28, Pages: 911-916, ISSN: 0301-5629

Journal article

Webb CM, Collins P, 2002, Androgens and arterial disease, Textbook of men's health, Editors: Lunenfeld, London, Publisher: Parthenon Publishing, Pages: 360-364, ISBN: 9781842140116

Book chapter

Hayward CS, Kraidly M, Webb CM, Collins Pet al., 2002, Assessment of endothelial function using peripheral waveform analysis: a clinical application, J Am Coll Cardiol, Vol: 40, Pages: 521-528, ISSN: 0735-1097

Journal article

Dixon K, Webb C, Malfroy J, 2001, Enhancing access to and retention in the Bachelor of Nursing: a successful alternative., Contemp Nurse, Vol: 11, Pages: 173-179, ISSN: 1037-6178

This paper describes an innovative program to enhance access to the Bachelor of Nursing (BN) in theform of a nursing entrance test (NET). Discussion will focus on the NET as the meansfor enhancing access and retention. The results of a recent evaluation of the NET are discussed and used to demonstrate that the NET is an effective tool for the provision of access and retention in the Bachelor of Nursing for students who do not meet standard entry criteria.

Journal article

Hayward CS, Webb CM, Collins P, 2001, Effect of sex hormones on cardiac mass, LANCET, Vol: 357, Pages: 1354-1356, ISSN: 0140-6736

Journal article

Adamson DL, Webb CM, Collins P, 2001, Esterified estrogens combined with methyltestosterone improve emotional well-being in postmenopausal women with chest pain and normal coronary angiograms, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, Vol: 8, Pages: 233-238, ISSN: 1072-3714

Journal article

Rosano GMC, Webb CM, Chierchia S, Morgani GL, Gabraele M, Sarrel PM, de Ziegler D, Collins Pet al., 2000, Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial effect of estrogen on exercise-induced myocardial ischemia in postmenopausal women, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 36, Pages: 2154-2159, ISSN: 0735-1097

Journal article

Figtree GA, Webb CM, Collins P, 2000, Tamoxifen acutely relaxes coronary arteries by an endothelium-, nitric oxide-, and estrogen receptor-dependent mechanism, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 295, Pages: 519-523, ISSN: 0022-3565

Journal article

Webb CM, Ghatei MA, McNeill JG, Collins Pet al., 2000, 17β-Estradiol decreases endothelin-1 levels in the coronary circulation of postmenopausal women with coronary artery disease, Circulation, Vol: 102, Pages: 1617-1622, ISSN: 0009-7322

Background - Estrogen reverses acetylcholine-induced coronary vasoconstriction via the possible facilitation of endothelium-derived NO. Estrogen also affects endothelium-derived constrictor factors. We therefore investigated the effects of 17β-estradiol on coronary vasomotor responses to substance P (SP), and coronary sinus endothelin-1 and NO metabolite levels in postmenopausal women with coronary heart disease. Methods and Results - We studied 20 women; 14 received estrogen (mean age 65±2 years) and 6 served as ethanol control subjects (age 63±3 years). Intracoronary infusions of papaverine (8 mg) and SP were administered before and 20 minutes after 50 pg/min 17β-estradiol or 0.2 μL/min control. Coronary blood flow was calculated from the diameter, as measured with quantitative coronary angiography, and flow velocity, as measured with intracoronary Doppler. Coronary sinus plasma endothelin-1 and nitrite/nitrate (NO2/NO3) were measured at baseline, at peak velocity response to each infusion, and every 5 minutes during the estradiol infusion. Endothelin-1 levels were decreased after 20 minutes of estradiol (1.12±0.18 versus 0.86±0.17 pmol/L baseline2 versus estradiol, P=0.05). Endothelin-1 levels to SP decreased after 17β-estradiol (1.29±0.18 versus 1.04±0.15 and 1.3±0.16 versus 0.99±0.17 pmol/L for before versus after estradiol, 10 and 25 pmol/min SP; both P<0.05). NO2/NO3 levels did not change. There was no change in vasomotor responses to estradiol alone or to papaverine or SP before versus after estradiol. Conclusions - Short-term intracoronary 17β-estradiol administration decreases coronary endothelino-1 levels. There was no enhancement of vasomotor responses to SP after the administration of estrogen, suggesting that the effects of estrogen on coronary acetylcholine responses may be a specific and not a generalized effect on coronary vasoreactivity.

Journal article

Webb CM, Ghatei MA, McNeill JG, Collins Pet al., 2000, 17β-estradiol decreases endothelin-l levels in the coronary circulation of postmenopausal women with coronary artery disease, CIRCULATION, Vol: 102, Pages: 1617-1622, ISSN: 0009-7322

Journal article

Figtree GA, Griffiths H, Liu YQ, Webb CM, MacLeod K, Collins Pet al., 2000, Plant-derived estrogens relax coronary arteries in vitro by a calcium antagonistic mechanism, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 35, Pages: 1977-1985, ISSN: 0735-1097

Journal article

Ong PJL, Patrizi G, Chong WCF, Webb CM, Hayward CS, Collins Pet al., 2000, Testosterone enhances flow-mediated brachial artery reactivity in men with coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 85, Pages: 269-272, ISSN: 0002-9149

Journal article

Webb CM, Hayward CS, Collins P, 2000, Changes in coronary arteries with estrogen therapy, The Management of the Menopause, Editors: Studd, Carnforth, UK, Publisher: Parthenon Publishing, Pages: 153-164, ISBN: 9781850700791

Book chapter

Pietras RJ, Szego CM, 1999, Cell membrane estrogen receptors resurface, NATURE MEDICINE, Vol: 5, Pages: 1330-1330, ISSN: 1078-8956

Journal article

Collins P, Webb C, 1999, Cell membrane estrogen receptors resurface -: <i>Collins and Webb reply</i>, NATURE MEDICINE, Vol: 5, Pages: 1330-1330, ISSN: 1078-8956

Journal article

Webb CM, McNeill JG, Hayward CS, de Zeigler D, Collins Pet al., 1999, Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease, CIRCULATION, Vol: 100, Pages: 1690-1696, ISSN: 0009-7322

Journal article

Collins P, Webb C, 1999, Estrogen hits the surface, NATURE MEDICINE, Vol: 5, Pages: 1130-1131, ISSN: 1078-8956

Journal article

Figtree GA, Lu YQ, Webb CM, Collins Pet al., 1999, Raloxifene acutely relaxes rabbit coronary arteries in vitro by an estrogen receptor-dependent and nitric oxide-dependent mechanism, CIRCULATION, Vol: 100, Pages: 1095-1101, ISSN: 0009-7322

Journal article

Hayward CS, Webb CM, Collins P, 1999, Hormone replacement therapy and heart-rate variability, LANCET, Vol: 354, Pages: 256-256, ISSN: 0140-6736

Journal article

Yuen KM, Pelayo R, 1999, Sleep disorders and attention-deficit/hyperactivity disorder, JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, Vol: 281, Pages: 797-797, ISSN: 0098-7484

Journal article

Webb CM, Adamson DL, de Zeigler D, Collins Pet al., 1999, Effect of acute testosterone on myocardial ischemia in men with coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 83, Pages: 437-+, ISSN: 0002-9149

Journal article

English L, Bonanno H, Ihnatko T, Webb C, Jones Jet al., 1999, Learning through writing in a first-year accounting course, Journal of Accounting Education, Vol: 17, Pages: 221-254, ISSN: 0748-5751

More than any other activity at a university, the writing experiences of students are directly linked to their academic progress. This paper reports on the practical steps taken in restructuring the curriculum of a first-year accounting course at the University of Sydney to develop students' writing skills within a broader skills-based program to enhance learning. Three dimensions of students' writing skills are addressed: writing skills as prerequisites for learning, writing skills as a means of learning, and writing skills as an outcome of learning. The paper explains how the educational theory about learning to write and writing to learn contributed to a pedagogical framework for teaching practice and gives several examples as illustration of the pedagogy. Interactive reading guides, annotated model answers, analysis grids, and formative self and peer assessment are among techniques adopted to encourage students to reflect actively on their own learning through writing. The curriculum redesign project reported here was first introduced in 1994, and substantially modified in 1995 in response to feedback. In general, the quality of submitted assignments, examination performance, and feedback from both staff and students suggests that the innovations reported in the paper have helped students to improve their writing skills and enabled them to become more engaged with the learning of the content of the course. Quantitative feedback between 1994-1997 confirms these conclusions. © 1999 Elsevier Science Ltd.

Journal article

Holford P, Webb C, Maltroy J, Conroy Jet al., 1999, Enhancing the research competencies of horticulture graduates through improved communications skills, HortTechnology, Vol: 9, Pages: 267-272, ISSN: 1063-0198

Research Philosophy and Methodology (RPM) is a core course designed for postgraduate students studying horticulture at the University of Western Sydney Hawkesbury. This course has two aims. First, RPM introduces the different paradigms found within science to students, and develops their understanding of different approaches to problem solving and extending knowledge. Second, RPM encourages an exploration of different forms of expression used within science and provides students with opportunities to practice communicating their ideas through written and oral presentations. It is intended that students will complete this course with a deeper understanding of how science is conducted and communicated.

Journal article

Webb CM, Collins P, 1999, Keeping in good heart, Orgyn, Vol: 10 (2), Pages: 6-9

Journal article

Webb CM, Rosano GMC, Collins P, 1998, Oestrogen improves exercise-induced myocardial ischaemia in women, LANCET, Vol: 351, Pages: 1556-1557, ISSN: 0140-6736

Journal article

Webb CM, Underwood R, Anagnostopoulos C, Bennett JG, Pepper J, Lincoln C, Collins Pet al., 1998, The effect of angiotensin converting enzyme inhibition on myocardial function and blood pressure after coronary artery bypass surgery - a randomised study, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 13, Pages: 42-48, ISSN: 1010-7940

Journal article

Rosano GMC, Caixeta AM, Chierchia S, Arie S, LopezHidalgo M, Pereira WI, Leonardo F, Webb CM, Pileggi F, Collins Pet al., 1997, Short-term anti-ischemic effect of 17 beta-estradiol in postmenopausal women with coronary artery disease, CIRCULATION, Vol: 96, Pages: 2837-2841, ISSN: 0009-7322

Journal article

Webb C, Collins P, 1997, Hormone therapy and cardiovascular dynamics, London, Publisher: Martin Dunitz, ISBN: 9781853174094

Book

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