Imperial College London

DrCarolynWebb

Faculty of MedicineNational Heart & Lung Institute

Research Fellow
 
 
 
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Contact

 

+44 (0)20 7351 8860c.webb Website

 
 
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Location

 

3013Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gaudino:2019:ejcts/ezz247,
author = {Gaudino, M and Benedetto, U and Fremes, S and Ballman, K and Biondi-Zoccai, G and Sedrakyan, A and Nasso, G and Raman, J and Buxton, B and Hayward, PA and Moat, N and Collins, P and Webb, C and Peric, M and Petrovic, I and Yoo, KJ and Hameed, I and Di, Franco A and Moscarelli, M and Speziale, G and Girardi, LN and Hare, DL and Taggart, DP},
doi = {ejcts/ezz247},
journal = {European Journal of Cardio-Thoracic Surgery},
pages = {1025--1030},
title = {The RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol},
url = {http://dx.doi.org/10.1093/ejcts/ezz247},
volume = {56},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - It is generally accepted that radial artery (RA) grafts have better mid-term patency rate compared to saphenous vein grafts. However, the clinical correlates of the improved patency rate are still debated. Observational studies have suggested increased survival and event-free survival for patients who receive an RA rather than a saphenous vein, but they are open to bias and confounders. The only evidence based on randomized data is a pooled meta-analysis of 6 randomized controlled trial comparing the RA and the saphenous vein published by the RADial artery International Alliance (RADIAL). In the RADIAL database, improved freedom from follow-up cardiac events (death, myocardial infarction and repeat revascularization) was found at 5-year follow-up in the RA arm. The most important limitation of the RADIAL analysis is that most of the included trials had an angiographic follow-up in the first 5 years and it is unclear whether the rate of repeat revascularization (the main driver of the composite outcome) was clinically indicated due to per-protocol angiographies. Here, we present the protocol for the long-term analysis of the RADIAL database. By extending the follow-up beyond the 5th postoperative year (all trials except 1 did not have angiographic follow-up beyond 5 years), we aim to provide data on the role of RA in coronary artery bypass surgery with respect to long-term outcomes.
AU - Gaudino,M
AU - Benedetto,U
AU - Fremes,S
AU - Ballman,K
AU - Biondi-Zoccai,G
AU - Sedrakyan,A
AU - Nasso,G
AU - Raman,J
AU - Buxton,B
AU - Hayward,PA
AU - Moat,N
AU - Collins,P
AU - Webb,C
AU - Peric,M
AU - Petrovic,I
AU - Yoo,KJ
AU - Hameed,I
AU - Di,Franco A
AU - Moscarelli,M
AU - Speziale,G
AU - Girardi,LN
AU - Hare,DL
AU - Taggart,DP
DO - ejcts/ezz247
EP - 1030
PY - 2019///
SN - 1010-7940
SP - 1025
TI - The RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol
T2 - European Journal of Cardio-Thoracic Surgery
UR - http://dx.doi.org/10.1093/ejcts/ezz247
UR - https://www.ncbi.nlm.nih.gov/pubmed/31535147
UR - http://hdl.handle.net/10044/1/73592
VL - 56
ER -