Dr. Yap's research work focus on cardiac biomechanics, especially with regards to embryonic and foetal hearts, where he investigates the role of mechanics in normal growth and during congenital heart malformations. He has novel contributions in studies on human foetal hearts via ultrasound-based flow and finite element simulations, and works with clinicians to advance foetal heart intervention as a treatment for congenital heart malformations.
Dr. Yap also researches materials strategies for cardiovascular medical devices, including haemostatic technologies, and anti-thrombotic materials for blood pumps, where he uses surface interaction properties to modulate thrombosis responses.
Dr. Choon Hwai Yap obtained his PhD from Georgia Institute of Technology, worked as a Postdoctoral Associate at University of Pittsburgh, and as an Assistant Professor at the National University of Singapore. He is an Editorial Board Member of Scientific Reports, and an Associate Editor for Medical and Biological Engineering and Computing.
et al., 2021, Biomechanics of human fetal hearts with critical aortic stenosis, Annals of Biomedical Engineering, Vol:49, ISSN:0090-6964, Pages:1364-1379
et al., 2021, Echocardiographic assessment of fetal cardiac function in the uterine artery ligation rat model of IUGR, Pediatric Research, ISSN:0031-3998
et al., 2020, Cardiac motion estimation from medical images: a regularisation framework applied on pairwise image registration displacement fields, Scientific Reports, Vol:10, ISSN:2045-2322
et al., 2020, 4D modelling of fluid mechanics in the zebrafish embryonic heart, Biomechanics and Modeling in Mechanobiology, Vol:19, ISSN:1617-7959, Pages:221-232
et al., 2019, Organ dynamics and hemodynamic of the whole HH25 avian embryonic heart, revealed by ultrasound biomicroscopy, boundary tracking, and flow simulations, Scientific Reports, Vol:9, ISSN:2045-2322, Pages:1-14