I am a Senior Research Fellow in the Section of Immunology of Infection. I obtained my BSc in Chemistry and my PhD in Biochemistry, working on the role of adenosine and adenosine deaminase in immunodeficiencies, at the University of Barcelona, Spain. I then joined the group of Prof. John P. Moore at the Weill Medical College of Cornell University, New York, USA. As a Postdoctoral Fellow, I had the opportunity to make my first steps in the field of HIV working in the areas of neutralizing antibodies and CCR5 co-receptor.
My primary research interests are mucosal infection and inflammation. Using ex vivo tissue models, I study mucosal responses during transmission of HIV/SIV, HCV, and Zika virus. These primary tissue models also allow pre-clinical evaluation of prevention strategies, including pre-exposure prophylaxis and vaccine candidates. I have recently expanded the potential of the ex vivo tissue models to investigate inflammation and associated pathologies such as Inflammatory Bowel Disease.
During the last 10 years, I have been funded as PI or co-investigator by amfAR, HVTN-CHAVI, EU Commission FP7 Health 2012 Innovation, EDCTP, NIH, Canadian Institute for Health Research, Manitoba Health Research, Henry Jackson Foundation, Pfizer, Gilead, Merck and CHAIN Biotechnology.
et al., 2020, Efficacy of silk fibroin biomaterial vehicle for in vivo mucosal delivery of Griffithsin and protection against HIV and SHIV infection ex vivo., J Int Aids Soc, Vol:23
et al., 2020, Assessing a novel, lab-free, point-of-care test for SARS-CoV-2 (CovidNudge): a diagnostic accuracy study., The Lancet Microbe, ISSN:2666-5247
et al., 2020, Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide., Sci Rep, Vol:10
et al., 2019, HIV Research for Prevention 2018: From research to impact: Conference summary and highlights, Aids Research and Human Retroviruses, Vol:35, ISSN:0889-2229, Pages:598-607
et al., 2019, CD32 expressing doublets in HIV infected gut-associated lymphoid are associated with a T follicular helper cell, Mucosal Immunology, Vol:12, ISSN:1933-0219, Pages:1212-1219