Collaborators
Moray Campbell, Ohio State University, Nuclear receptor cofactors in prostate cancer, 2019
Dr Ralf Zwack and Dr Greg Brooke, University of Essex, MSC-mediated delivery of TRAIL for the treatment of prostate cancer, 2018 - 2021
Prof Mark Emberton, Dr Gert Attard, University College London, Movember/Prostate Cancer UK Centre of Excellence in Prostate cancer Research, 2013
Tapio Visakorpi, University of Tampere, MicroRNAs in prostate cancer and androgen signalling, 2012
Prof Johann de Bono and prof Ros Eles, Institute of Cancer Research, Movember/Prostate Cancer UK Centre of Excellence in Prostate cancer Research, 2011
Eva Estebanez Perpina, Institut de Biomedicina-Universitat de Barcelona (IBUB), Structural aspects of androgen receptor signalling, 2011
Prof Paul Rennie, Vancouver Prostate Cancer Centre, 2011
Dr Amanda Swain, Institute of Cancer Research, Models for prostate cancer, 2010
Craig Robson and Luke Gaughan, Northern Institute for Cancer Research, University of Newcastle, Prostate cancer biomarkers and new therapeutic targets, 2010
Dr Ian Mills, University of Oxford, Non-coding RNAs in prostate cancer. Genomic responses to androgen receptor activation, 2009
Prof. Frank Claessens, University of Leuven
Borja Belandia, Instituto de Investigaciones Biomedicas, Madrid
Prof. A. O. Brinkmann, Erasmus University, Rotterdam
Guest Lectures
New approaches to inhibit androgen signalling in prostate cancer, Prostate Cancer - From Bench to the Clinic, Oslo, Norway, 2015
New approaches to inhibiting androgen signalling in prostate cancer, ENDO 2014, Chicago, USA, 2014
New approaches to inhibit the androgen receptor pathway in prostate cancer, French Association for Prostate Cancer Research, Annual Scientific Meeting, Paris, 2013
Androgen signalling in prostate cancer and beyond, Queen's University, Belfast, 2013
Androgens: what they do and how to stop them, University of Aberdeen, Aberdeen, 2013
Inhibiting androgen receptor function in prostate cancer, European Association of Urology Annual Meeting, Strasbourg, 2012
Role Of Corepressors In Androgen Regulation Of Prostatic Tumours, 14th International Congress of Hormonal Steroids and Hormones & Cancer, Edinburgh, 2010
Inhibiting androgen receptor signalling in prostate cancer, TMDU (Tokyo Medical and Dental University), Tokyo, 2009
In vivo repression of androgen receptor activity in prostate cancer, Erasmus University, Rotterdam, 2008
Mechanisms of androgen receptor activation and repression, Androgens 2006, Cambridge, UK, 2006
Mechanisms of action of therapeutic antiandrogens, BioScience 2006, Glasgow, 2006
Hey1, a mediator of Notch signalling, is an androgen receptor corepressor, Androgens 2004 (Conference), Berlin, 2004
Hey1: linking androgen and Notch signalling, Institute of Cancer Research, Sutton, 2004
Androgen receptor signalling in prostate cancer, 5th World Urological Congress, London, 2003
Androgen receptor signalling in prostate cancer, 5th World Urological Congress, London, 2003
Androgen receptor antagonists: mechanisms of action, Joint Workshop on AR and GR, Ghent, Belgium, 2003
Androgen receptor action in prostate cancer, University College London, London, 2003
Androgen and antiandrogen action in the prostate, Androgens 2002, Leuven, Belgium, 2002
Hormone therapy and the progression of prostate cancer to hormone independence, Edinburgh International Science Festival, Edinburgh, 2001
Transcriptional activation by the androgen receptor, Androgen 2000, Rotterdam, Netherlands, 2000
Transcriptional activation by oestrogen and androgen receptors, Xth International Congress on Hormonal Steroids, Quebec City, Canada, 1998
Overview of androgen action in the prostate, British Endocrine Societies, Mar 2003
Research Staff
Brooke,GN
Dart,DA
Fernandes,R
Gadaleta,R
Lavery,DN
Powell,SM
Sita-Lumsden,A
Research Student Supervision
Allen,M, Hydrogel responsive vesicles for drug delivery
Brooke,G, Androgen receptor variants in prostate cancer progression
Broomfield,J, Development of a Lab-on-Chip System for Detection and Quantification of Circulating mRNA in Prostate Cancer using Isothermal Amplification Methods
Chotai,D, The role of Prohibitin in Androgen Signalling and Prostate Cancer
Constantin,T, Transcriptional inhibition in prostate cancer therapy
Culley,R, The role of the RNA-binding protein FUS in androgen signalling
Eringyte,I, Systematic Identification of MicroRNA Drivers of Resistance to Novel Therapeutics in Advanced Prostate Cancer – Exploitation as Stratification Biomarkers and Drug Targets
Fioretti,F, Therapeutic repressors of androgen receptor
Fletcher,C, Interactions of Prohibitin and MicroRNA27a in the Androgen Signalling Pathway
Garcao-Nunes,J, Investigating the role of sphingosine kinase 1 pathway in cancer cell-monocyte interactions
Gatehouse,A, Cell free DNA size analysis using engineered hydrogel nanopore sensors: a non-invasive diagnostic tool for cancer
Hindley,J, Development of phospholipase- and uv-responsive vesicles for applications in drug delivery and synthetic biology
Jaffer,T, The Effects of Anaesthetics on Ovarian Cancer Malignancy
Jarvis,S, Study of metabolic nuclear receptors in testis
Kalofonou,F, Characterisation of AR-modulatory microRNAs in Prostate Cancer
Mazor,M, Characterisation of the Wnt signalling component in prostate cancer cells
Metcalf,G, Fluorogenic Peptide Nucleic Acid probes for the detection of circulating microRNA: applications to cancer diagnosis
Querol Cano,L, The role of the co-chaperone p23 in Androgen Receptor activity and Prostate cancer
Rana,S, Systematic analysis of prognostic and predictive miRNA-mRNA networks in Prostate Cancer
Reebye,V, Identification and characterisation of androgen rector-associated cytoplasmic proteins
Shibakawa,A, Investigating circulating miRNAs as predictors of therapeutic response in metastatic castration-resistant prostate cancer
Sita-Lumsden,A, The role of Prohibitin and miR-27a in prostate cancer progression and therapy response
Tam,J, Exosomal communication linking obesity and prostate cancer
Teahan,O, A Metabonomic Approach to Biomarker Discovery in Prostate Cancer
Thomas,P-M, Circulating nucleic acids in prostate cancer
Whitaker,H, Androgen receptor-interacting proteins in prostate cancer
Zamarbide,J, Identification of MicroRNAs that Alter Cell Death in Treatment-Resistant and –Responsive Breast Cancer