Summary
Chloe Bloom is a NIHR Clinician Scientist at the National Heart and Lung Institute, working in the field of respiratory epidemiology, and a Honorary Respiratory Consultant at Imperial College Healthcare NHS Trust. She read Medicine at the University of Manchester and graduated with Honours in Research and a BSc in Biological Sciences from Imperial College London.
She undertook specialist respiratory training in North West London and during this period she was awarded a MRC Clinical Research Training Fellow for her doctoral studies. She carried out her PhD at the MRC-National Institute for Medical Research under Professor Anne O'Garra FRS where she applied bioinformatics and biostatistics to evaluate genomic and clinical data from respiratory patients. After receiving her CCT she obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine.
Chloe joined Imperial College London in 2017 on a NHLI fellowship as a clinical postdoctoral epidemiologist. Her research interests are centered on the use of large clinical data to improve the management of respiratory disease, with a focus on adult and paediatric asthma, as well as other respiratory diseases including COVID-19 and COPD.
Chloe was awarded a prestigious NIHR Advanced Fellowship in 2021 to lead a programme of research in asthma, involving the application of quantitative and qualitative analysis, and a data-driven pragmatic trial.
Selected Publications
Journal Articles
Stewart I, Bloom C, 2021, Considerations for conducting and interpreting long-term follow-up of intervention studies: avoiding spoiled milk, Thorax, Vol:76, ISSN:0040-6376, Pages:1067-1068
Bloom CI, Johnston SL, 2021, Decline in respiratory and cardiac admissions during the COVID-19 pandemic: what is the role of common respiratory virus infections?, Respirology, Vol:26, ISSN:1323-7799, Pages:1010-1011
Bloom CI, Cullinan P, Wedzicha JA, 2021, Asthma phenotypes and COVID-19 risk: a population-based observational study, American Journal of Respiratory and Critical Care Medicine, Vol:205, ISSN:1073-449X, Pages:36-45
Bloom C, Franklin C, Bush A, et al., 2021, Burden of preschool wheeze and progression to asthma in the UK: population-based cohort 2007 to 2017, Journal of Allergy and Clinical Immunology, Vol:147, ISSN:0091-6749, Pages:1949-1958
Bloom C, Tom D, Docherty A, et al., Risk of adverse outcomes in patients with underlying respiratory conditions hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: a national, multicentre prospective cohort, The Lancet Respiratory Medicine, ISSN:2213-2600
Bloom C, de Preux L, Sheikh A, et al., 2020, Health and cost impact of stepping down asthma medication for UK patients, 2001–2017: a population-based observational study, PLOS Medicine, Vol:17, ISSN:1549-1277
Bloom C, douglas I, Olney J, et al., 2019, Cost saving of switching to equivalent inhalers and its effect on health outcomes, Thorax, Vol:74, ISSN:1468-3296, Pages:1078-1086
Bloom C, Saglani S, Feary J, et al., 2019, Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population based cohort 2006 to 2016, European Respiratory Journal, Vol:53, ISSN:0903-1936, Pages:1-8
Bloom CI, Palmer T, Feary J, et al., 2018, Exacerbation patterns in adults with asthma in England: A population based study, American Journal of Respiratory and Critical Care Medicine, Vol:199, ISSN:1073-449X, Pages:446-453
Dunning J, Blankley S, Hoang LT, et al., 2018, Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza, Nature Immunology, Vol:19, ISSN:1529-2916, Pages:625-635
Bloom CI, Nissen F, Douglas IJ, et al., 2018, Exacerbation risk and characterisation of the UK’s asthma population, from infants to old age, Thorax, Vol:73, ISSN:1468-3296, Pages:313-320
Bloom C, Slaich B, Morales DR, et al., 2018, Low uptake of palliative care support for COPD patients within primary care in the UK, European Respiratory Journal, Vol:51, ISSN:0903-1936
Bloom CI, Graham CM, Berry MPR, et al., 2013, Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers, PLOS One, Vol:8, ISSN:1932-6203
Bloom CI, Graham CM, Berry MPR, et al., 2012, Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy, PLOS One, Vol:7, ISSN:1932-6203
Conference
Bloom CI, Nissen F, Douglas I, et al., Characteristics of a large nationally representative UK primary care asthma population and their incidence and determinants of asthma exacerbations, American Thoracic Society