Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Clinical Senior Lecturer in Respiratory Epidemiology







Emmanuel Kaye BuildingRoyal Brompton Campus





Chloe Bloom is a NIHR Clinician Scientist and group leader at NHLI, working in the field of respiratory epidemiology. She is an Honorary Consultant in Respiratory Medicine at Imperial College Healthcare NHS Trust working in integrated respiratory care and specialist asthma clinics. 

She read Medicine at the University of Manchester and graduated with Honours in Research and a BSc in Biological Sciences from Imperial College London. Chloe undertook specialist respiratory training in North West London and was awarded a MRC Clinical Research Training Fellow. She carried out her PhD at the MRC-National Institute for Medical Research under Professor Anne O'Garra FRS, applying bioinformatics and biostatistics to evaluate genomic and clinical data from respiratory patients. After receiving her CCT she obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine.

Chloe joined Imperial College London in 2017 on a NHLI fellowship. She was awarded a prestigious NIHR Advanced Fellowship in 2021 to lead a programme of research in asthma related to the use of asthma medication, involving quantitative and qualitative approaches and a data-driven pragmatic trial. 

The research interests of her group are centred on the use of large clinical data to improve the management of respiratory disease, with a focus on adult and paediatric asthma, as well as other respiratory diseases including covid-19 and COPD. Her teaching roles include Respiratory Lead for Imperial College Medical School final years and supervision of BSc and MSc students.

Selected Publications

Journal Articles

Conway FM, Bloom CI, Shah PL, 2022, Susceptibility of patients with airways disease to SARS-CoV-2 infection., American Journal of Respiratory and Critical Care Medicine, Vol:206, ISSN:1073-449X, Pages:696-703

Bloom CI, Cullinan P, Wedzicha JA, 2021, Asthma phenotypes and COVID-19 risk: a population-based observational study, American Journal of Respiratory and Critical Care Medicine, Vol:205, ISSN:1073-449X, Pages:36-45

Bloom CI, Drake TM, Docherty AB, et al., 2021, Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK, The Lancet Respiratory Medicine, Vol:9, ISSN:2213-2600, Pages:699-711

Bloom C, Franklin C, Bush A, et al., 2021, Burden of preschool wheeze and progression to asthma in the UK: population-based cohort 2007 to 2017, Journal of Allergy and Clinical Immunology, Vol:147, ISSN:0091-6749, Pages:1949-1958

Bloom C, de Preux L, Sheikh A, et al., 2020, Health and cost impact of stepping down asthma medication for UK patients, 2001–2017: a population-based observational study, PLOS Medicine, Vol:17, ISSN:1549-1277

Bloom C, douglas I, Olney J, et al., 2019, Cost saving of switching to equivalent inhalers and its effect on health outcomes, Thorax, Vol:74, ISSN:1468-3296, Pages:1078-1086

Bloom C, Saglani S, Feary J, et al., 2019, Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population based cohort 2006 to 2016, European Respiratory Journal, Vol:53, ISSN:0903-1936, Pages:1-8

Bloom CI, Palmer T, Feary J, et al., 2018, Exacerbation patterns in adults with asthma in England: A population based study, American Journal of Respiratory and Critical Care Medicine, Vol:199, ISSN:1073-449X, Pages:446-453

Dunning J, Blankley S, Hoang LT, et al., 2018, Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza, Nature Immunology, Vol:19, ISSN:1529-2916, Pages:625-635

Bloom CI, Nissen F, Douglas IJ, et al., 2018, Exacerbation risk and characterisation of the UK’s asthma population, from infants to old age, Thorax, Vol:73, ISSN:1468-3296, Pages:313-320

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