Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Senior Clinical Research Fellow







Guy Scadding BuildingRoyal Brompton Campus





Chloe Bloom is a clinical academic working in the field of respiratory epidemiology. She completed her specialist respiratory training in North West London in 2014. During this time she undertook a PhD as a MRC Clinical Research Training Fellow at the MRC-National Institute for Medical Research under Professor Anne O'Garra FRS, where she applied bioinformatics and biostatistics in the evaluation of genomic and clinical data. After receiving her CCT she obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine. Her research interests centre on the use of large clinical data to improve management of respiratory disease, with a focus on asthma, as well as other respiratory diseases including COPD. She is an Honorary Respiratory Consultant at Imperial College Healthcare NHS Trust and Royal Brompton Hospital.

Selected Publications

Journal Articles

Bloom C, Tom D, Docherty A, et al., Risk of adverse outcomes in patients with underlying respiratory conditions hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: a national, multicentre prospective cohort, The Lancet Respiratory Medicine, ISSN:2213-2600

Bloom C, Franklin C, Bush A, et al., 2021, Burden of preschool wheeze and progression to asthma in the UK: population-based cohort 2007 to 2017, Journal of Allergy and Clinical Immunology, ISSN:0091-6749

Patel R, Naqvi S, Griffiths C, et al., 2020, Systemic adverse effects from inhaled corticosteroid use in asthma: a systematic review, Bmj Open Respiratory Research, Vol:7, ISSN:2052-4439

Bloom C, Ramsey H, Alter M, et al., 2020, Qualitative study of practices and challenges of stepping down asthma medication in primary care across the UK, Journal of Asthma and Allergy, Vol:13, ISSN:1178-6965, Pages:429-437

Bloom C, de Preux L, Sheikh A, et al., 2020, Health and cost impact of stepping down asthma medication for UK patients, 2001–2017: a population-based observational study, PLOS Medicine, Vol:17, ISSN:1549-1277

Sundaram V, Bloom C, Zakeri R, et al., 2019, Temporal trends in the incidence, treatment patterns, and outcomes of coronary artery disease and peripheral artery disease in the United Kingdom, 2006-2015, European Heart Journal, Vol:41, ISSN:0195-668X, Pages:1636-1649

Bloom C, douglas I, Olney J, et al., 2019, Cost saving of switching to equivalent inhalers and its effect on health outcomes, Thorax, Vol:74, ISSN:1468-3296, Pages:1078-1086

Bloom C, Ricciardi F, Smeeth L, et al., 2019, Predicting COPD one year mortality using prognostic predictors routinely measured in primary care, BMC Medicine, Vol:17, ISSN:1741-7015

Bloom C, Saglani S, Feary J, et al., 2019, Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population based cohort 2006 to 2016, European Respiratory Journal, Vol:53, ISSN:0903-1936, Pages:1-8

Bloom CI, Palmer T, Feary J, et al., 2018, Exacerbation patterns in adults with asthma in England: A population based study, American Journal of Respiratory and Critical Care Medicine, Vol:199, ISSN:1073-449X, Pages:446-453

Dunning J, Blankley S, Hoang LT, et al., 2018, Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza, Nature Immunology, Vol:19, ISSN:1529-2916, Pages:625-635

Bloom CI, Nissen F, Douglas IJ, et al., 2018, Exacerbation risk and characterisation of the UK’s asthma population, from infants to old age, Thorax, Vol:73, ISSN:1468-3296, Pages:313-320

Bloom C, Slaich B, Morales DR, et al., 2018, Low uptake of palliative care support for COPD patients within primary care in the UK, European Respiratory Journal, Vol:51, ISSN:0903-1936

Bloom CI, Graham CM, Berry MPR, et al., 2013, Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers, PLOS One, Vol:8, ISSN:1932-6203

Bloom CI, Graham CM, Berry MPR, et al., 2012, Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy, PLOS One, Vol:7, ISSN:1932-6203


Bloom CI, Nissen F, Douglas I, et al., Characteristics of a large nationally representative UK primary care asthma population and their incidence and determinants of asthma exacerbations, American Thoracic Society

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