DrChloeBloom

Faculty of Medicine, National Heart & Lung Institute

Clinical Senior Lecturer in Respiratory Epidemiology

Contact

Location

Emmanuel Kaye BuildingRoyal Brompton Campus

Summary

Chloe Bloom is a NIHR Clinician Scientist and group leader at NHLI, working in the field of respiratory epidemiology. She is an Honorary Consultant in Respiratory Medicine at Imperial College Healthcare NHS Trust working in integrated respiratory care and specialist asthma clinics. Her teaching roles including Respiratory Lead for Imperial College Medical School years 5 & 6 and supervision of BSc and MSc students.

She read Medicine at the University of Manchester and graduated with Honours in Research and a BSc in Biological Sciences from Imperial College London. Chloe undertook specialist respiratory training in North West London and was awarded a MRC Clinical Research Training Fellow. She carried out her PhD at the MRC-National Institute for Medical Research under Professor Anne O'Garra FRS, applying bioinformatics and biostatistics to evaluate genomic and clinical data from respiratory patients. After receiving her CCT she obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine.

Chloe joined Imperial College London in 2017 on a NHLI fellowship. She was awarded a prestigious NIHR Advanced Fellowship in 2021 to lead a programme of research in asthma related to the use of asthma medication, involving quantitative and qualitative approaches and a data-driven pragmatic trial.

The research interests of her group are centered on the use of large clinical data to improve the management of respiratory disease, with a focus on adult and paediatric asthma, as well as other respiratory diseases including covid-19 and COPD.

Selected Publications

Journal Articles

Conway FM, Bloom CI, Shah PL, 2022, Susceptibility of patients with airways disease to SARS-CoV-2 infection., American Journal of Respiratory and Critical Care Medicine, Vol:206, ISSN:1073-449X, Pages:696-703

Stewart I, Bloom C, 2021, Considerations for conducting and interpreting long-term follow-up of intervention studies: avoiding spoiled milk, Thorax, Vol:76, ISSN:0040-6376, Pages:1067-1068

Bloom CI, Johnston SL, 2021, Decline in respiratory and cardiac admissions during the COVID-19 pandemic: what is the role of common respiratory virus infections?, Respirology, Vol:26, ISSN:1323-7799, Pages:1010-1011

Bloom CI, Cullinan P, Wedzicha JA, 2021, Asthma phenotypes and COVID-19 risk: a population-based observational study, American Journal of Respiratory and Critical Care Medicine, Vol:205, ISSN:1073-449X, Pages:36-45

Bloom CI, Drake TM, Docherty AB, et al.Bloom CI, Drake TM, Docherty AB, Lipworth BJ, Johnston SL, Nguyen-Van-Tam JS, Carson G, Dunning J, Harrison EM, Baillie JK, Semple MG, Cullinan P, Openshaw PJM, Alex B, Bach B, Barclay WS, Bogaert D, Chand M, Cooke GS, Filipe AD, Fletcher T, Green CA, Harrison EM, Hiscox JA, Ho AY, Horby PW, Ijaz S, Khoo S, Klenerman P, Law A, Lim WS, Mentzer AJ, Merson L, Meynert AM, Noursadeghi M, Moore SC, Palmarini M, Paxton WA, Pollakis G, Price N, Rambaut A, Robertson DL, Russell CD, Sancho-Shimizu V, Scott JT, Silva TD, Sigfrid L, Solomon T, Sriskandan S, Stuart D, Summers C, Tedder RS, Thomson EC, Thompson AAR, Thwaites RS, Turtle LCW, Zambon M, Hardwick H, Donohue C, Lyons R, Griffiths F, Oosthuyzen W, Norman L, Pius R, Fairfield CJ, Knight SR, Mclean KA, Murphy D, Shaw CA, Dalton J, Girvan M, Saviciute E, Roberts S, Harrison J, Marsh L, Connor M, Halpin S, Jackson C, Gamble C, Leeming G, Law A, Wham M, Clohisey S, Hendry R, Scott-Brown J, Greenhalf W, Shaw V, McDonald S, Keating S, Ahmed KA, Armstrong JA, Ashworth M, Asiimwe IG, Bakshi S, Barlow SL, Booth L, Brennan B, Bullock K, Catterall BWA, Clark JJ, Clarke EA, Cole S, Cooper L, Cox H, Davis C, Dincarslan O, Dunn C, Dyer P, Elliott A, Evans A, Finch L, Fisher LWS, Foster T, Garcia-Dorival I, Greenhalf W, Gunning P, Hartley C, Jensen RL, Jones CB, Jones TR, Khandaker S, King K, Kiy RT, Koukorava C, Lake A, Lant S, Latawiec D, Lavelle-Langham L, Lefteri D, Lett L, Livoti LA, Mancini M, McDonald S, McEvoy L, McLauchlan J, Metelmann S, Miah NS, Middleton J, Mitchell J, Moore SC, Murphy EG, Penrice-Randal R, Pilgrim J, Prince T, Reynolds W, Ridley PM, Sales D, Shaw VE, Shears RK, Small B, Subramaniam KS, Szemiel A, Taggart A, Tanianis-Hughes J, Thomas J, Trochu E, Tonder LV, Wilcock E, Zhang JE, Flaherty L, Maziere N, Cass E, Carracedo AD, Carlucci N, Holmes A, Massey H, Adeniji K, Agranoff D, Agwuh K, Ail D, Alegria A, Angus B, Ashish A, Atkinson D, Bari S, Barlow G, Barnass S, Barrett N, Bassford C, Baxter D, Beadsworth M, Bernatoniene J, Berridge J, Best N, Bothma P, Brealey D, Brittain-Long R, Bulteel N, Burden T, Burtenshaw A, Caruth V, Chadwick D, Chambler D, Chee N, Child J, Chukkambotla S, Clark T, Collini P, Cosgrove C, Cupitt J, Cutino-Moguel M, Dark P, Dawson C, Dervisevic S, Donnison P, Douthwaite S, DuRand I, Dushianthan A, Dyer T, Evans C, Eziefula C, Fegan C, Finn A, Fullerton D, Garg S, Garg S, Garg A, Gkrania-Klotsas E, Godden J, Goldsmith A, Graham C, Hardy E, Hartshorn S, Harvey D, Havalda P, Hawcutt DB, Hobrok M, Hodgson L, Hormis A, Jacobs M, Jain S, Jennings P, Kaliappan A, Kasipandian V, Kegg S, Kelsey M, Kendall J, Kerrison C, Kerslake I, Koch O, Koduri G, Koshy G, Laha S, Laird S, Larkin S, Leiner T, Lillie P, Limb J, Linnett V, Little J, MacMahon M, MacNaughton E, Mankregod R, Masson H, Matovu E, McCullough K, McEwen R, Meda M, Mills G, Minton J, Mirfenderesky M, Mohandas K, Mok Q, Moon J, Moore E, Morgan P, Morris C, Mortimore K, Moses S, Mpenge M, Mulla R, Murphy M, Nagel M, Nagarajan T, Nelson M, Otahal I, Pais M, Panchatsharam S, Paraiso H, Patel B, Pattison N, Pepperell J, Peters M, Phull M, Pintus S, Pooni J, Post F, Price D, Prout R, Rae N, Reschreiter H, Reynolds T, Richardson N, Roberts M, Roberts D, Rose A, Rousseau G, Ryan B, Saluja T, Shah A, Shanmuga P, Sharma A, Shawcross A, Sizer J, Shankar-Hari M, Smith R, Snelson C, Spittle N, Staines N, Stambach T, Stewart R, Subudhi P, Szakmany T, Tatham K, Thomas J, Thompson C, Thompson R, Tridente A, Tupper-Carey D, Twagira M, Ustianowski A, Vallotton N, Vincent-Smith L, Visuvanathan S, Vuylsteke A, Waddy S, Wake R, Walden A, Welters I, Whitehouse T, Whittaker P, Whittington A, Wijesinghe M, Williams M, Wilson L, Wilson S, Winchester S, Wiselka M, Wolverson A, Wooton DG, Workman A, Yates B, Young P close, 2021, Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK, The Lancet Respiratory Medicine, Vol:9, ISSN:2213-2600, Pages:699-711

Bloom C, Franklin C, Bush A, et al.Bloom C, Franklin C, Bush A, Saglani S, Quint J close, 2021, Burden of preschool wheeze and progression to asthma in the UK: population-based cohort 2007 to 2017, Journal of Allergy and Clinical Immunology, Vol:147, ISSN:0091-6749, Pages:1949-1958

Bloom C, de Preux L, Sheikh A, et al.Bloom C, de Preux L, Sheikh A, Quint J close, 2020, Health and cost impact of stepping down asthma medication for UK patients, 2001–2017: a population-based observational study, PLOS Medicine, Vol:17, ISSN:1549-1277

Bloom C, douglas I, Olney J, et al.Bloom C, douglas I, Olney J, d'Ancona G, smeeth L, Quint J close, 2019, Cost saving of switching to equivalent inhalers and its effect on health outcomes, Thorax, Vol:74, ISSN:1468-3296, Pages:1078-1086

Bloom C, Saglani S, Feary J, et al.Bloom C, Saglani S, Feary J, Jarvis D, Quint J close, 2019, Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population based cohort 2006 to 2016, European Respiratory Journal, Vol:53, ISSN:0903-1936, Pages:1-8

Bloom CI, Palmer T, Feary J, et al.Bloom CI, Palmer T, Feary J, Quint JK, Cullinan P close, 2018, Exacerbation patterns in adults with asthma in England: A population based study, American Journal of Respiratory and Critical Care Medicine, Vol:199, ISSN:1073-449X, Pages:446-453

Dunning J, Blankley S, Hoang LT, et al.Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ, Moffatt MF, O’Garra A, Openshaw PJM close, 2018, Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza, Nature Immunology, Vol:19, ISSN:1529-2916, Pages:625-635

Bloom CI, Nissen F, Douglas IJ, et al.Bloom CI, Nissen F, Douglas IJ, Smeeth L, Cullinan P, Quint JK close, 2018, Exacerbation risk and characterisation of the UK’s asthma population, from infants to old age, Thorax, Vol:73, ISSN:1468-3296, Pages:313-320

Bloom C, Slaich B, Morales DR, et al.Bloom C, Slaich B, Morales DR, Smeeth L, Stone P, Quint JK close, 2018, Low uptake of palliative care support for COPD patients within primary care in the UK, European Respiratory Journal, Vol:51, ISSN:0903-1936

Bloom CI, Graham CM, Berry MPR, et al.Bloom CI, Graham CM, Berry MPR, Rozakeas F, Redford PS, Wang Y, Xu Z, Wilkinson KA, Wilkinson RJ, Kendrick Y, Devouassoux G, Ferry T, Miyara M, Bouvry D, Dominique V, Gorochov G, Blankenship D, Saadatian M, Vanhems P, Beynon H, Vancheeswaran R, Wickremasinghe M, Chaussabel D, Banchereau J, Pascual V, Ho L-P, Lipman M, O'Garra A close, 2013, Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers, PLOS One, Vol:8, ISSN:1932-6203

Bloom CI, Graham CM, Berry MPR, et al.Bloom CI, Graham CM, Berry MPR, Wilkinson KA, Oni T, Rozakeas F, Xu Z, Rossello-Urgell J, Chaussabel D, Banchereau J, Pascual V, Lipman M, Wilkinson RJ, O'Garra A close, 2012, Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy, PLOS One, Vol:7, ISSN:1932-6203

Conference

Bloom CI, Nissen F, Douglas I, et al.Bloom CI, Nissen F, Douglas I, Smeeth L, Cullinan P, Quint JKQ close, Characteristics of a large nationally representative UK primary care asthma population and their incidence and determinants of asthma exacerbations, American Thoracic Society

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