Imperial College London


Faculty of MedicineSchool of Public Health

Reader in Chronic and Complex Diseases



christopher.butler Website




Department of Brain SciencesSir Michael Uren HubWhite City Campus





Chris Butler MA PhD FRCP is Clinical Senior Lecturer in Dementia Research at Imperial College London. 

He leads the Global Brain Health research group in the Department of Brain Sciences in the Faculty of Medicine.

His research programme aims to improve the diagnosis and clinical outcomes of people with cognitive disorders, particularly those living in disadvantaged communities in the UK and in low- and middle-income countries. 

He is Principal Investigator of the NIHR-funded IMPACT Dementia project, which is developing innovative approaches to dementia and its co-morbidities for health systems in Latin America. In the UK, his research group employs cognitive testing, mobile health technologies, non-invasive brain stimulation and advanced neuroimaging to explore novel diagnostic, support and treatment strategies for people with cognitive disorders and their families. His work lies at the interface between neuroscience and public policy, promoting cognitive capital as a key driver towards healthier and wealthier societies.

Dr Butler is a practising neurologist in the Imperial Memory Service at Charing Cross Hospital, Imperial College Healthcare NHS Trust. His area of expertise is in cognitive disorders and he has particular interests in the diagnosis and management of neurodegenerative diseases, epilepsy and transient amnesic syndromes. 

He is Visiting Professor of Neurology at the Pontificia Universidad Católica, Santiago, Chile; Associate Researcher at the Instituto de Neurociencias Cognitivas, Buenos Aires, Argentina and Honorary Senior Fellow at The George Institute for Global Health. He is Past President of the British Neuropsychiatry Association, the leading academic and professional body for professionals in the UK working at the interface of the clinical and cognitive neurosciences and psychiatry.



Linnemann C, Wilke C, Mengel D, et al., 2024, NfL reliability across laboratories, stage-dependent diagnostic performance and matrix comparability in genetic FTD: a large GENFI study., J Neurol Neurosurg Psychiatry

Chapleau M, La Joie R, Yong K, et al., 2024, Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis., Lancet Neurol, Vol:23, Pages:168-177

Benussi A, Premi E, Grassi M, et al., 2024, Diagnostic accuracy of research criteria for prodromal frontotemporal dementia., Alzheimers Res Ther, Vol:16

Alegret M, García-Gutiérrez F, Muñoz N, et al., 2024, FACEmemory®, an Innovative Online Platform for Episodic Memory Pre-Screening: Findings from the First 3,000 Participants., J Alzheimers Dis, Vol:97, Pages:1173-1187

Ullgren A, Öijerstedt L, Olofsson J, et al., 2023, Altered plasma protein profiles in genetic FTD - a GENFI study., Mol Neurodegener, Vol:18

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