Imperial College London

Dr Chris Dunsby

Faculty of Natural SciencesDepartment of Physics

Professor of Biomedical Optics



+44 (0)20 7594 7755christopher.dunsby Website




622Blackett LaboratorySouth Kensington Campus






BibTex format

author = {Harput, S and Christensen-Jeffries, K and Ramalli, A and Brown, J and Zhu, J and Zhang, G and Leow, CH and Toulemonde, M and Boni, E and Tortoli, P and Eckersley, RJ and Dunsby, C and Tang, M-X},
title = {3-D super-resolution ultrasound (SR-US) imaging with a 2-D sparse array},
url = {},
year = {2019}

RIS format (EndNote, RefMan)

AB - High frame rate 3-D ultrasound imaging technology combined withsuper-resolution processing method can visualize 3-D microvascular structuresby overcoming the diffraction limited resolution in every spatial direction.However, 3-D super-resolution ultrasound imaging using a full 2-D arrayrequires a system with large number of independent channels, the design ofwhich might be impractical due to the high cost, complexity, and volume of dataproduced. In this study, a 2-D sparse array was designed and fabricated with 512elements chosen from a density-tapered 2-D spiral layout. High frame ratevolumetric imaging was performed using two synchronized ULA-OP 256 researchscanners. Volumetric images were constructed by coherently compounding 9-angleplane waves acquired in 3 milliseconds at a pulse repetition frequency of 3000Hz. To allow microbubbles sufficient time to move between consequent compoundedvolumetric frames, a 7-millisecond delay was introduced after each volumeacquisition. This reduced the effective volume acquisition speed to 100 Hz andthe total acquired data size by 3.3-fold. Localization-based 3-Dsuper-resolution images of two touching sub-wavelength tubes were generatedfrom 6000 volumes acquired in 60 seconds. In conclusion, this work demonstratesthe feasibility of 3D super-resolution imaging and super-resolved velocitymapping using a customized 2D sparse array transducer.
AU - Harput,S
AU - Christensen-Jeffries,K
AU - Ramalli,A
AU - Brown,J
AU - Zhu,J
AU - Zhang,G
AU - Leow,CH
AU - Toulemonde,M
AU - Boni,E
AU - Tortoli,P
AU - Eckersley,RJ
AU - Dunsby,C
AU - Tang,M-X
PY - 2019///
TI - 3-D super-resolution ultrasound (SR-US) imaging with a 2-D sparse array
UR -
UR -
ER -