Imperial College London
Portrait Picture

Professor Chris Dunsby

Faculty of Natural Sciences, Department of Physics

Professor of Biomedical Optics
 
 
 
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Contact

 

+44 (0)20 7594 7755christopher.dunsby Website

 
 
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Location

 

622Blackett LaboratorySouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Zhang:2019:10.1109/ULTSYM.2019.8926069,
author = {Zhang, G and Harput, S and Toulemonde, M and Broughton-Venner, J and Zhu, J and Riemer, K and Christensen-Jeffries, K and Brown, J and Eckersley, RJ and Weinberg, P and Dunsby, C and Tang, M-X},
doi = {10.1109/ULTSYM.2019.8926069},
pages = {1930--1933},
publisher = {IEEE},
title = {Acoustic wave sparsely-activated localization microscopy (AWSALM): in vivo fast ultrasound super-resolution imaging using nanodroplets},
url = {http://dx.doi.org/10.1109/ULTSYM.2019.8926069},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - CPAPER
AB  - Current localization-based super-resolution ultrasound imaging requires a low concentration of flowing microbubbles to visualize microvasculature beyond the diffraction limit and acquisition is slow. Nanodroplets offer a promising solution as they can be sparsely activated and deactivated on-demand. In this study, acoustic wave sparsely-activated localization microscopy (AWSALM) using activation and deactivation of nanodroplets, an acoustic counterpart of photo-activated localization microscopy (PALM) which is less dependent on agent concentration and the presence of flow, is demonstrated for super-resolution imaging in deep tissues in vivo. An in vivo super-resolution image of a rabbit kidney is obtained in 1.1 seconds using AWSALM, where micro-vessels with apparent sizes far below the half-wavelength of 220 μm were visualized. This preliminary result demonstrates the feasibility of applying AWSALM for in vivo super-resolution imaging.
AU  - Zhang,G
AU  - Harput,S
AU  - Toulemonde,M
AU  - Broughton-Venner,J
AU  - Zhu,J
AU  - Riemer,K
AU  - Christensen-Jeffries,K
AU  - Brown,J
AU  - Eckersley,RJ
AU  - Weinberg,P
AU  - Dunsby,C
AU  - Tang,M-X
DO  - 10.1109/ULTSYM.2019.8926069
EP  - 1933
PB  - IEEE
PY  - 2019///
SN  - 1948-5719
SP  - 1930
TI  - Acoustic wave sparsely-activated localization microscopy (AWSALM): in vivo fast ultrasound super-resolution imaging using nanodroplets
UR  - http://dx.doi.org/10.1109/ULTSYM.2019.8926069
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000510220100494&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://ieeexplore.ieee.org/document/8926069
ER  -
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