Imperial College London
Alternate

Mr Colin D Bicknell BM MD FRCS

Faculty of Medicine, Department of Surgery & Cancer

Clinical Reader in Vascular Surgery
 
 
 
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Contact

 

+44 (0)20 3312 6428colin.bicknell

 
 
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Location

 

1020Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Normahani:2021:10.1177/0267659121995760,
author = {Normahani, P and Anwar, IY and Courtney, A and Acharya, A and Sounderajah, V and Mustafa, C and Jaffer, U and Shalhoub, J and Riga, C and Gibbs, R and Jenkins, M and Bicknell, C and Davies, AH and Nott, D and Aylwin, C and Standfield, NJ},
doi = {10.1177/0267659121995760},
journal = {Perfusion (United Kingdom)},
pages = {276--283},
title = {Factors associated with infrainguinal bypass graft patency at 1-year; a retrospective analysis of a single centre experience},
url = {http://dx.doi.org/10.1177/0267659121995760},
volume = {37},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Introduction:The aim of this study was to identify factors associated with primary graft patency 1 year following open lower limb revascularisation (LLR) at a tertiary referral vascular service.Methods:A retrospective analysis of patients undergoing infra-inguinal bypass surgery between January 2016 and May 2017 at a tertiary vascular centre (St Mary’s Hospital, London) was performed. Data regarding patient demographics, comorbidities, type of operation and post-operative anti-thrombotic strategy were collected. Quality of run-off score was assessed from pre-operative imaging.Results:Seventy-seven cases were included in the analysis. Overall, the primary patency rate at 1-year was 63.6% (n = 49/77) and the secondary patency rate was 67.5% (n = 52/77). Independent variables with statistically significant inferior patency rates at 1-year were (1) bypasses with below knee targets (p = 0.0096), (2) chronic limb threatening ischaemia indication (p = 0.038), (3) previous ipsilateral revascularisation (p < 0.001) and (4) absence of hypertension history (p = 0.041). There was also a trend towards significance for American Society of Anesthesiologists (ASA) grade (p = 0.06). Independent variables with log-rank test p values of <0.1 were included in a Cox proportional hazards model. The only variable with a statistically significant impact on primary patency rates was previous open or endovascular ipsilateral revascularisation (HR 2.44 (1.04–5.7), p = 0.04).Conclusion:At 1-year follow-up, previous ipsilateral revascularisation was the most significant factor in affecting patency rates. Patients in this subgroup should therefore be deemed high-risk, which should be reflected in the informed consent and peri-operative management.
AU  - Normahani,P
AU  - Anwar,IY
AU  - Courtney,A
AU  - Acharya,A
AU  - Sounderajah,V
AU  - Mustafa,C
AU  - Jaffer,U
AU  - Shalhoub,J
AU  - Riga,C
AU  - Gibbs,R
AU  - Jenkins,M
AU  - Bicknell,C
AU  - Davies,AH
AU  - Nott,D
AU  - Aylwin,C
AU  - Standfield,NJ
DO  - 10.1177/0267659121995760
EP  - 283
PY  - 2021///
SN  - 1477-111X
SP  - 276
TI  - Factors associated with infrainguinal bypass graft patency at 1-year; a retrospective analysis of a single centre experience
T2  - Perfusion (United Kingdom)
UR  - http://dx.doi.org/10.1177/0267659121995760
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000628398200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://journals.sagepub.com/doi/10.1177/0267659121995760
UR  - http://hdl.handle.net/10044/1/96958
VL  - 37
ER  -
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